Article
Psychology, Developmental
Adelar Pedro Franz, Arthur Caye, Barbara Calil Lacerda, Flavia Wagner, Rita C. Silveira, Renato Soibelmann Procianoy, Carlos Renato Moreira-Maia, Luis Augusto Rohde
Summary: The study developed an individualized risk calculator for ADHD in VP/VLBW newborns, which showed good performance in identifying high-risk children at 6 years old. This tool could offer more effective early intervention compared to traditional approaches.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Pediatrics
Christine Strand Bachmann, Kari Risnes, Johan Hakon Bjorngaard, Jorun Schei, Kristine Pape
Summary: The study examines the impact of relative age on mental health, specifically in preterm infants. The results show that being relatively young within a school class is associated with an increased likelihood of psychostimulant prescription, and this effect persists into young adulthood for preterm individuals.
Article
Multidisciplinary Sciences
Oliver Perra, Fiona Alderdice, David Sweet, Alison McNulty, Matthew Johnston, Delfina Bilello, Kostas Papageorgiou, Sam Wass
Summary: Very preterm infants are at risk of cognitive delays and lower educational attainments. This study examines the feasibility of early interventions targeting attention functioning in VP infants and observes moderate positive effects in certain aspects of attention. However, no relevant gains were found in attention habituation or disengagement. The study highlights the utility of Bayesian approaches in estimating potential effects in small samples or exploratory studies.
Article
Pediatrics
Dustin D. Flannery, Erika M. Edwards, Karen M. Puopolo, Jeffrey D. Horbar
Summary: This study investigated the epidemiology and microbiology of early-onset sepsis (EOS) among very preterm infants from 2018 to 2019. The findings revealed an incidence rate of 13.5 per 1000 very preterm births, with Escherichia coli and group B Streptococcus being the most common pathogens. Infected infants had longer hospital stays and lower survival rates, emphasizing the need for novel preventive strategies.
Article
Clinical Neurology
Winnie Wan-Yee Tso, Frederick Ka Wing Ho, David Coghill, Tatia Mei-Chun Lee, Yuliang Wang, So-Lun Lee, Mabel Siu-Chun Wong, Jason Cheuk Sing Yam, Ian Chi Kei Wong, Patrick Ip
Summary: This study aims to investigate the association between the risk of attention-deficit/hyperactivity disorder (ADHD) and preterm birth, as well as determine the relationship between postnatal complications in children born preterm and the risk of ADHD. The findings suggest that children born preterm in all subcategories, from extremely preterm to late preterm, have an increased risk of ADHD. Early respiratory infection partially mediates the risk of ADHD in children born preterm.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2022)
Article
Public, Environmental & Occupational Health
Casey Crump, Jan Sundquist, Kristina Sundquist
Summary: This study aimed to examine the risks of ADHD in preterm and early term birth survivors and found that both preterm and early term birth were associated with increased risks of ADHD in males and females, independently of other covariates and shared familial factors.
ANNALS OF EPIDEMIOLOGY
(2023)
Article
Pediatrics
Dustin D. Flannery, Erika M. Edwards, Sarah A. Coggins, Jeffrey D. Horbar, Karen M. Puopolo
Summary: This study examines the epidemiology, microbiology, and outcomes of late-onset sepsis among very preterm infants in the United States. The findings reveal a significant proportion of infants suffering from late-onset sepsis, particularly those born at the lowest gestational ages. Infected infants have higher mortality rates and survivors are at increased risk of technology-dependent chronic morbidities.
Article
Neurosciences
Azadeh Kushki, Robyn E. Cardy, Sina Panahandeh, Mahan Malihi, Christopher Hammill, Jessica Brian, Alana Iaboni, Margot J. Taylor, Russell Schachar, Jennifer Crosbie, Paul Arnold, Elizabeth Kelley, Muhammad Ayub, Robert Nicolson, Stelios Georgiades, Jason P. Lerch, Evdokia Anagnostou
Summary: The study discovered associations between social communication abilities and distributed cortical and subcortical networks implicated in social behaviors, language, attention, memory, and executive functions, as well as three data-driven, diagnosis-agnostic subgroups based on the patterns of association in these networks.
Article
Multidisciplinary Sciences
Vanessa Siffredi, Maria Chiara Liverani, Petra Susan Huppi, Lorena G. A. Freitas, Jiske De Albuquerque, Fanny Gimbert, Arnaud Merglen, Djalel Eddine Meskaldji, Cristina Borradori Tolsa, Russia Ha-Vinh Leuchter
Summary: The study aimed to evaluate the effectiveness of mindfulness-based intervention (MBI) in improving executive, behavioral, and socio-emotional abilities in very preterm (VPT) children and adolescents. The results showed a beneficial effect of MBI on these competencies, especially in enhancing executive abilities. The findings suggest that MBI could be a valuable tool for reducing the detrimental consequences of prematurity in young adolescents.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Xi Chen, Xiaoli Zhang, Wenhua Li, Wendong Li, Yong Wang, Shan Zhang, Changlian Zhu
Summary: Preterm births with different etiologies are associated with varying neonatal complications, but no differences in neurodevelopmental outcomes were observed at 12 months of corrected age.
FRONTIERS IN NEUROLOGY
(2021)
Article
Obstetrics & Gynecology
Pablo Navalon, Farah Ghosn, Maite Ferrin, Belen Almansa, Alba Moreno-Gimenez, Laura Campos-Berga, Rosa Sahuquillo-Leal, Vicente Diago, Maximo Vento, Ana Garcia-Blanco
Summary: Infants born after suspected preterm labor have a higher risk of developing attention deficit hyperactivity disorder symptoms, including those born at term. These infants exhibit distinct behavioral features and share specific risk factors.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Review
Medicine, General & Internal
Sahar Sharif, Sam J. Oddie, Paul T. Heath, William McGuire
Summary: This review aims to evaluate the effectiveness of enteral supplementation with prebiotic oligosaccharides on the risk of necrotising enterocolitis, and associated morbidity and mortality, in very preterm or very low birth weight infants.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Letter
Medicine, General & Internal
De-Kun Li
Summary: The study investigated the association between maternal exposure to magnetic field nonionizing radiation during pregnancy and the risk of attention-deficit/hyperactivity disorder in offspring in a longitudinal birth cohort. However, for certain reasons, the study results have been retracted and replaced.
Article
Pediatrics
Mathilde Letouzey, Laurence Foix-L'Helias, Heloise Torchin, Ayoub Mitha, Andrei S. Morgan, Jennifer Zeitlin, Gilles Kayem, Emeline Maisonneuve, Pierre Delorme, Babak Khoshnood, Monique Kaminski, Pierre-Yves Ancel, Pascal Boileau, Elsa Lorthe
Summary: The study found that the risk of late-onset sepsis in very preterm infants differs according to the cause of preterm birth, with infants born after hypertensive disorders or fetal growth restriction having a higher risk compared to those born after preterm labor. Antenatal factors, particularly the various causes leading to preterm birth, should be considered to better prevent and manage neonatal infectious morbidity and inform parents.
PEDIATRIC RESEARCH
(2021)
Review
Psychology, Developmental
Angelica Ronald, Nora de Bode, Tinca J. C. Polderman
Summary: Research on the association between ADHD polygenic risk score (PRS) and ADHD-related traits in both clinical and population samples has shown strong evidence of a link in various aspects such as ADHD, brain structure, education, externalizing behaviors, and more. However, associations with addiction, autism, and mental health remain inconclusive and require further investigation.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2021)
Review
Pediatrics
Rachel Robinson, Polina Girchenko, Anna Pulakka, Kati Heinonen, Anna Lahdepuro, Marius Lahti-Pulkkinen, Petteri Hovi, Marjaana Tikanmaki, Peter Bartmann, Aulikki Lano, Lex W. Doyle, Peter J. Anderson, Jeanie L. Y. Cheong, Brian A. Darlow, Lianne J. Woodward, L. John Horwood, Marit S. Indredavik, Kari Anne Evensen, Neil Marlow, Samantha Johnson, Marina Goulart de Mendonca, Eero Kajantie, Dieter Wolke, Katri Raikkonen
Summary: This study examined the differences in ADHD symptoms and diagnosis between preterm and term-born adults and found that while preterm adults may not report higher levels of ADHD symptoms, they have a higher risk of receiving an ADHD diagnosis in adulthood.
PEDIATRIC RESEARCH
(2023)
Article
Acoustics
Bronacha Mylrea-Foley, Hans Wolf, Tamara Stampalija, Christoph Lees
ULTRASCHALL IN DER MEDIZIN
(2023)
Article
Communication
Chloe Shaw, Kathrina Connabeer, Paul Drew, Katie Gallagher, Narendra Aladangady, Neil Marlow
Summary: This study reports the development and evaluation of a new coding framework for researching neonatal end-of-life decision making conversations. The framework was developed through a qualitative analysis of recordings and showed moderate to strong agreement between coders. The coding confirmed the importance of doctors' talk in parental involvement in decision-making and highlighted areas for further analysis.
HEALTH COMMUNICATION
(2023)
Editorial Material
Pediatrics
Joan K. Morris, Nicholas J. Wald
ARCHIVES OF DISEASE IN CHILDHOOD
(2023)
Review
Obstetrics & Gynecology
Adalina Sacco, Emily F. Cornish, Neil Marlow, Anna L. David, Dino A. Giussani
Summary: According to a systematic review of human clinical literature, antenatal corticosteroids (ACS) exposure does not have long-term effects on cardiovascular function in human offspring. However, due to the limited number, heterogeneity, and mixed quality of studies, the effects on cardiac structure and other measures of cardiac function remain unclear. Further research is needed to assess central cardiac function in human offspring exposed to ACS.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Pediatrics
Jonathan S. Litt, Samantha Johnson, Neil Marlow, Henning Tiemeier
Summary: This study aimed to investigate whether poor childhood pulmonary function explains the association between extremely preterm birth and attention-deficit/hyperactivity disorder symptoms in young adulthood. The results showed that extremely preterm individuals had a higher risk of inattention compared to term-born peers, and this risk may be related to poor pulmonary function.
Article
Pediatrics
Kathy Chant, Maria Bitner-Glindzicz, Neil Marlow
Summary: This case-control study investigated the individual and concomitant risk factors for hearing loss in neonatal care. The results showed that lower birth weight for gestational age, more severe neonatal illness, increased medication exposure, and physiological risk factors were associated with hearing loss.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2023)
Article
Developmental Biology
Ester Garne, Stine Kjaer Urhoj, Marian Bakker, Mika Gissler, Joanne Given, Anna Heino, Elisabeth Limb, Maria Loane, Hermien de Walle, Joan Morris
Summary: This study evaluated the quality and accuracy of codes identifying termination of pregnancy for fetal anomalies (TOPFA) cases in hospital databases. The results showed that hospital databases have limited information or codes to accurately identify specific anomalies in TOPFA cases, but can be used to identify the occurrence of a TOPFA and obtain more detailed information from medical records.
BIRTH DEFECTS RESEARCH
(2023)
Article
Obstetrics & Gynecology
Sophie C. Relph, Matias Vieira, Andrew Copas, Chivon Winsloe, Kirstie Coxon, Alessandro Alagna, Annette Briley, Mark Johnson, Louise Page, Donald Peebles, Andrew Shennan, Baskaran Thilaganathan, Neil Marlow, Christoph A. Lees, Deborah Lawlor, Asma Khalil, Jane Sandall, Dharmintra Pasupathy
Summary: This study aimed to determine whether the use of the Growth Assessment Protocol (GAP) affects the antenatal detection of large for gestational age (LGA) babies and their maternal and perinatal outcomes. The study found that there were no significant differences in the rate of LGA detection or any of the maternal and perinatal outcomes between the GAP and standard care groups.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Clinical Neurology
Triona Casey, Aoife Jones Thachuthara, Leanna Fogarty, Vicki Livingstone, Michelle De Haan, Neil Marlow, Mairead E. Kiely, Deirdre M. Murray
Summary: The aim of this study was to validate a touchscreen assessment as a screening tool for mild cognitive delay in typically developing children aged 24 months. The results showed that the touchscreen assessment had moderate concurrent validity with the Bayley Scales of Infant and Toddler Development, and could reasonably identify mild cognitive delay among typically developing children.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Pediatrics
Ingrid Marie Husby Hollund, Kristina Anna Djupvik Aakvik, Silje Dahl Benum, Sigrid Hegna Ingvaldsen, Stian Lydersen, Marjaana Tikanmaki, Petteri Hovi, Katri Raikkonen, Eero Kajantie, Samantha Johnson, Neil Marlow, Nicole Baumann, Dieter Wolke, Marit S. Indredavik, Kari Anne I. Evensen
Summary: The associations between mental health, pain, and tiredness in adults are independent of gestation or birthweight. Further research should explore other potential mechanisms to explain the increased risk of mental health problems in the preterm population.
Article
Psychology, Developmental
Jennifer Larsen, Puja Kochhar, Dieter Wolke, Elizabeth S. Draper, Neil Marlow, Samantha Johnson
Summary: This study investigates whether the behavioral outcomes of extremely preterm (EP) children have changed over time with increasing survival rates. It compares the behavioral outcomes at age 11 for two national cohorts of EP children born in 1995 (EPICure) and 2006 (EPICure2), along with term-born children. The results show that EP children have higher mean scores and more clinically significant difficulties compared to term-born children in almost all measures. Furthermore, the behavioral outcomes for EP children born in 2006 are worse than those born in 1995. Long-term clinical follow-up and psychological support are needed for EP children.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Developmental Biology
Ann-Louise Rud Andersen, Stine Kjaer Urhoj, Joachim Tan, Clara Cavero-Carbonell, Miriam Gatt, Mika Gissler, Kari Klungsoyr, Babak Khoshnood, Joan Morris, Amanda J. Neville, Anna Pierini, Ieuan Scanlon, Hermien E. K. de Walle, Diana Wellesley, Ester Garne, Maria Loane
Summary: This population-based data-linkage cohort study investigated the mortality and morbidity for the first 5 years of life in European children diagnosed with Turner syndrome. The results showed that the burden of disease was relatively high in the first year, but decreased afterwards.
BIRTH DEFECTS RESEARCH
(2023)
Article
Pediatrics
Joanne Given, Joan K. Morris, Ester Garne, Elisa Ballardini, Laia Barrachina-Bonet, Clara Cavero-Carbonell, Mika Gissler, Francesca Gorini, Anna Heino, Sue Jordan, Amanda J. Neville, Anna Pierini, Ieuan Scanlon, Joachim Tan, Stine K. Urhoj, Maria Loane
Summary: This study aimed to evaluate the prescription rates of insulin/insulin analogues in children aged 0-9 years with and without major congenital anomalies. The results showed that children with chromosomal anomalies had an increased risk of developing diabetes requiring insulin therapy, while children with non-chromosomal anomalies had a similar risk to the reference group. Female children had a reduced risk, and preterm births without congenital anomalies were more likely to be prescribed insulin/insulin analogues.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Medicine, Research & Experimental
Rebecca Spencer, Kasia Maksym, Kurt Hecher, Karel Marsal, Francesc Figueras, Gareth Ambler, Harry Whitwell, Nuno Rocha Nene, Neil J. Sebire, Stefan R. Hansson, Anke Diemert, Jana Brodszki, Eduard Gratacos, Yuval Ginsberg, Tal Weissbach, Donald M. Peebles, Ian Zachary, Neil Marlow, Angela Huertas-Ceballos, Anna L. David
Summary: This study investigates the use of maternal serum protein and ultrasound measurements to predict outcomes in pregnancies affected by severe, early-onset fetal growth restriction (FGR). The results demonstrate that ultrasound measurements and maternal serum PlGF concentration can predict important pregnancy outcomes for patients and clinicians.
JOURNAL OF CLINICAL INVESTIGATION
(2023)