A unified statistical potential reveals that amino acid stickiness governs nonspecific recruitment of client proteins into condensates

The key role of solvent in condensation: Mapping water in liquid-liquid phase-separated FUS

(2021) Jonas Ahlers et al.   BIOPHYSICAL JOURNAL

Determinants for intrinsically disordered protein recruitment into phase-separated protein condensates

(2021) Yongsang Jo et al.   Chemical Science

Valence and patterning of aromatic residues determine the phase behavior of prion-like domains

(2020) Erik W. Martin et al.   SCIENCE

Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties

(2020) Gregory L. Dignon et al.   Annual Review of Physical Chemistry

Dehydration entropy drives liquid-liquid phase separation by molecular crowding

(2020) Sohee Park et al.   Communications Chemistry

How do intrinsically disordered protein regions encode a driving force for liquid–liquid phase separation?

(2020) Wade Borcherds et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain

(2019) Anastasia C. Murthy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes

(2019) Giorgia Celetti et al.   JOURNAL OF CELL BIOLOGY

Surface Properties Determining Passage Rates of Proteins through Nuclear Pores

(2018) Steffen Frey et al.   CELL

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

(2018) Seema Qamar et al.   CELL

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

Sequence determinants of protein phase behavior from a coarse-grained model

(2018) Gregory L. Dignon et al.   PLoS Computational Biology

Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs

(2017) Yuan Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PDB-wide identification of biological assemblies from conserved quaternary structure geometry

(2017) Sucharita Dey et al.   NATURE METHODS

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A novel index of protein-protein interface propensity improves interface residue recognition

(2016) Wentao Dai et al.   BMC Systems Biology

Biological membranes

(2015) H. Watson   Essays in Biochemistry

The CamSol Method of Rational Design of Protein Mutants with Enhanced Solubility

(2015) Pietro Sormanni et al.   JOURNAL OF MOLECULAR BIOLOGY

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity

(2015) Hermann Broder Schmidt et al.   eLife

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

The use of interatomic contact areas to quantify discrepancies between RNA 3D models and reference structures

(2014) Kliment Olechnovič et al.   NUCLEIC ACIDS RESEARCH

Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles

(2014) David Zwicker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the Importance of Polar Interactions for Complexes Containing Intrinsically Disordered Proteins

(2013) Eric T. C. Wong et al.   PLoS Computational Biology

The Permeability of Reconstituted Nuclear Pores Provides Direct Evidence for the Selective Phase Model

(2012) Bastian B. Hülsmann et al.   CELL

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Cellular crowding imposes global constraints on the chemistry and evolution of proteomes

(2012) E. D. Levy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How to build a robust intracellular concentration gradient

(2012) Martin Howard   TRENDS IN CELL BIOLOGY

Pathway and mechanism of drug binding to G-protein-coupled receptors

(2011) Ron O. Dror et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

(2011) C. P. Brangwynne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinating cell polarity with cell division in space and time

(2011) Costanza Panbianco et al.   TRENDS IN CELL BIOLOGY

In VivoFormation of Protein Based Aqueous Microcompartments

(2009) Xin Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE