On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review

Crystallization Behavior and Crystallographic Properties of dl-Arabinose and dl-Xylose Diastereomer Sugars

(2022) Bradley Tyson et al.   CRYSTAL GROWTH & DESIGN

A prebiotically plausible scenario of an RNA–peptide world

(2022) Felix Müller et al.   NATURE

Synthesis of Amino Acids from Aldehydes and Ammonia: Implications for Organic Reactions in Carbonaceous Chondrite Parent Bodies

(2022) Toshiki Koga et al.   ACS Earth and Space Chemistry

Spontaneous Deracemizations

(2021) Thomas Buhse et al.   CHEMICAL REVIEWS

Emergence of homochirality in large molecular systems

(2021) Gabin Laurent et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Emergence of RNA from the Heterogeneous Products of Prebiotic Nucleotide Synthesis

(2021) Seohyun Chris Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Open questions in understanding life’s origins

(2021) Christopher J. Butch et al.   Communications Chemistry

Illuminating Life’s Origins: UV Photochemistry in Abiotic Synthesis of Biomolecules

(2021) Nicholas J. Green et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Insight into the Origin of Stereoselectivity in the Ribose-Mediated Strecker Synthesis of Alanine

(2021) Luca Legnani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Timescales for Prebiotic Photochemistry Under Realistic Surface Ultraviolet Conditions

(2021) Paul B. Rimmer et al.   ASTROBIOLOGY

Magneto‐chiral anisotropy: From fundamentals to perspectives

(2021) Matteo Atzori et al.   CHIRALITY

Symmetry and Chirality: Where Physics Shakes Hands with Chemistry and Biology

(2021) Laurence D. Barron   ISRAEL JOURNAL OF CHEMISTRY

A Threose Nucleic Acid Enzyme with RNA Ligase Activity

(2021) Yao Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Approach to the De Novo Synthesis of Life

(2021) Sijbren Otto   ACCOUNTS OF CHEMICAL RESEARCH

UV Transmission in Natural Waters on Prebiotic Earth

(2021) Sukrit Ranjan et al.   ASTROBIOLOGY

Mechanistic Insight into Metal Ion-Catalyzed Transamination

(2021) Robert J. Mayer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cross-Chiral, RNA-Catalyzed Exponential Amplification of RNA

(2021) Grant A. L. Bare et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Applications of Carbohydrate-Based Organocatalysts

(2021) Elżbieta Wojaczyńska et al.   MOLECULES

A Prebiotic Ribosylation of Pyrimidine Nucleobases Enabled by Metal Cations and Clay Minerals

(2021) Qian-Qian Chen et al.   Life-Basel

On the Role of Water as a Catalyst in Prebiotic Chemistry

(2020) José M. Saa et al.   CHEMPHYSCHEM

Catalytic Gels for a Prebiotically Relevant Asymmetric Aldol Reaction in Water: From Organocatalyst Design to Hydrogel Discovery and Back Again

(2020) Kirsten Hawkins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prebiotic Astrochemistry and the Formation of Molecules of Astrobiological Interest in Interstellar Clouds and Protostellar Disks

(2020) Scott A. Sandford et al.   CHEMICAL REVIEWS

Wavelength dependence of chiral recognition using ions between photoexcited tryptophan and sugars

(2020) Hiromori Murashima et al.   CHEMICAL PHYSICS

The Messy Alkaline Formose Reaction and Its Link to Metabolism

(2020) Arthur Omran et al.   Life-Basel

Boron in Prebiological Evolution: a Rising Star of the XXI Century

(2020) José da Silva et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cometary Glycolaldehyde as a Source of Pre-RNA Molecules

(2020) Nicolle E.B. Zellner et al.   ASTROBIOLOGY

Mineral-mediated carbohydrate synthesis by mechanical forces in a primordial geochemical setting

(2020) Maren Haas et al.   Communications Chemistry

Autocatalysis in Formose Reaction and Formation of RNA Nucleosides

(2020) Yassin Aweis Jeilani et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Hydroxymethanesulfonate from Volcanic Sulfur Dioxide. A “Mineral” Reservoir for Formaldehyde and Other Simple Carbohydrates in Prebiotic Chemistry

(2019) J. Kawai et al.   ASTROBIOLOGY

The Origin of Biological Homochirality

(2019) Donna G. Blackmond   Cold Spring Harbor Perspectives in Biology

Formation of Glyoxylic Acid in Interstellar Ices: A Key Entry Point for Prebiotic Chemistry

(2019) André K. Eckhardt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analyses of Aliphatic Aldehydes and Ketones in Carbonaceous Chondrites

(2019) José C. Aponte et al.   ACS Earth and Space Chemistry

Electrochirogenesis: The Possible Role of Low-Energy Spin-Polarized Electrons in Creating Homochirality

(2019) Rosenberg   Symmetry-Basel

Revisiting the language of glycoscience: readers, writers and erasers in carbohydrate biochemistry

(2019) Simone Dedola et al.   CHEMBIOCHEM

Interactions of Amino Acids and Aminoxazole Derivatives: Cocrystal Formation and Prebiotic Implications Enabled by Computational Analysis

(2019) Nieves Lavado et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Chemical Basis of Biological Homochirality during the Abiotic Evolution Stages on Earth

(2019) Josep M. Ribó et al.   Symmetry-Basel

The Search for Chiral Asymmetry as a Potential Biosignature in our Solar System

(2019) Daniel P. Glavin et al.   CHEMICAL REVIEWS

Spontaneous Resolution and Super-coiling in Xerogels of the Products of Photo-Induced Formose Reaction

(2019) Sergey V. Stovbun et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Extraterrestrial ribose and other sugars in primitive meteorites

(2019) Yoshihiro Furukawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autocatalytic Models for the Origin of Biological Homochirality

(2019) Donna G. Blackmond   CHEMICAL REVIEWS

Strecker reaction and α-amino nitriles: Recent advances in their chemistry, synthesis, and biological properties

(2018) Vladimir V. Kouznetsov et al.   TETRAHEDRON

Gas-phase sugar formation using hydroxymethylene as the reactive formaldehyde isomer

(2018) André K. Eckhardt et al.   Nature Chemistry

Mathematical modeling reveals spontaneous emergence of self-replication in chemical reaction systems

(2018) Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deoxyribose and deoxysugar derivatives from photoprocessed astrophysical ice analogues and comparison to meteorites

(2018) Michel Nuevo et al.   Nature Communications

Nucleic acids: function and potential for abiogenesis

(2017) Falk Wachowius et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Comment on “Ribose and related sugars from ultraviolet irradiation of interstellar ice analogs”

(2017) Jun Kawai   SCIENCE

Response to Comment on “Ribose and related sugars from ultraviolet irradiation of interstellar ice analogs”

(2017) Cornelia Meinert et al.   SCIENCE

Chiral Sugars Drive Enantioenrichment in Prebiotic Amino Acid Synthesis

(2017) Alexander J. Wagner et al.   ACS Central Science

Influence of the UV Environment on the Synthesis of Prebiotic Molecules

(2016) Sukrit Ranjan et al.   ASTROBIOLOGY

Enantiomer excesses of rare and common sugar derivatives in carbonaceous meteorites

(2016) George Cooper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribose and related sugars from ultraviolet irradiation of interstellar ice analogs

(2016) C. Meinert et al.   SCIENCE

The Origin of Life-Out of the Blue

(2015) John D. Sutherland   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbohydrate-Based Organocatalysts: Recent Developments and Future Perspectives

(2015) Amrita Mishra et al.   CURRENT ORGANIC SYNTHESIS

Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism

(2015) Bhavesh H. Patel et al.   Nature Chemistry

Effects of Silicate, Phosphate, and Calcium on the Stability of Aldopentoses

(2015) Sakiko Nitta et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Catalytic Formation of Monosaccharides: From the Formose Reaction towards Selective Synthesis

(2014) Irina V. Delidovich et al.   ChemSusChem

Conformational and H-Bonding Preferences for Facile Racemate Crystallization of Ribose

(2014) Ewa Patyk et al.   CHIRALITY

Deuterium Studies Reveal a New Mechanism for the Formose Reaction Involving Hydride Shifts

(2014) Chandrakumar Appayee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluating the Plausibility of Prebiotic Multistage Syntheses

(2013) Alan W. Schwartz   ASTROBIOLOGY

Prebiotic Systems Chemistry: New Perspectives for the Origins of Life

(2013) Kepa Ruiz-Mirazo et al.   CHEMICAL REVIEWS

Catalysis of Glyceraldehyde Synthesis by Primary or Secondary Amino Acids Under Prebiotic Conditions as a Function of pH

(2013) Ronald Breslow et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

The Role of Carbohydrates at the Origin of Homochirality in Biosystems

(2013) Søren Toxvaerd   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

On the Origin of Single Chirality of Amino Acids and Sugars in Biogenesis

(2012) Jason E. Hein et al.   ACCOUNTS OF CHEMICAL RESEARCH

On the Prebiotic Synthesis of D-Sugars Catalyzed by L-Peptides: Assessments from First-Principles Calculations

(2012) David Cantillo et al.   CHEMISTRY-A EUROPEAN JOURNAL

dl-Ribose Crystal Structures: the GlassCrystal Transformation

(2012) Giorgia Zandomeneghi et al.   HELVETICA CHIMICA ACTA

Multicomponent Assembly of Proposed DNA Precursors in Water

(2012) Matthew W. Powner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploratory Experiments on the Chemistry of the “Glyoxylate Scenario”: Formation of Ketosugars from Dihydroxyfumarate

(2012) Vasudeva Naidu Sagi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prebiotic synthesis of simple sugars by photoredox systems chemistry

(2012) Dougal Ritson et al.   Nature Chemistry

Diastereoselective Self-Condensation of Dihydroxyfumaric Acid in Water: Potential Route to Sugars

(2011) Vasudeva Naidu Sagi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Etiology of Potentially Primordial Biomolecular Structures: From Vitamin B12 to the Nucleic Acids and an Inquiry into the Chemistry of Life’s Origin: A Retrospective

(2011) Albert Eschenmoser   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Crystalline Architectures as Templates of Relevance to the Origins of Homochirality

(2011) Isabelle Weissbuch et al.   CHEMICAL REVIEWS

Organocatalytic synthesis of carbohydrates

(2011) Jacek Mlynarski et al.   CHEMICAL SOCIETY REVIEWS

On the Chiral Homogeneity of Nature: From Atoms to Small Molecules

(2011) Cristóbal Viedma et al.   ISRAEL JOURNAL OF CHEMISTRY

Synthesis of Carbohydrates in Mineral-Guided Prebiotic Cycles

(2011) Hyo-Joong Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Different substrate-dependent transition states in the active site of the ribosome

(2011) Stephan Kuhlenkoetter et al.   NATURE

A route to enantiopure RNA precursors from nearly racemic starting materials

(2011) Jason E. Hein et al.   Nature Chemistry

Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions

(2011) Laurence Burroughs et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Crystal Structure of D-Ribose-At Last!

(2010) Dubravka Šišak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective Multicomponent One-Pot Assembly of Purine Precursors in Water

(2010) Matthew W. Powner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

L-amino acids catalyze the formation of an excess of D-glyceraldehyde, and thus of other D sugars, under credible prebiotic conditions

(2010) R. Breslow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Planetary Organic Chemistry and the Origins of Biomolecules

(2010) S. A. Benner et al.   Cold Spring Harbor Perspectives in Biology

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

(2009) Matthew W. Powner et al.   NATURE

Stereoselective Syntheses of Pentose Sugars Under Realistic Prebiotic Conditions

(2009) Sandra Pizzarello et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Homochirality in Life: Two Equal Runners, One Tripped

(2009) Mark M. Green et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Carbohydrate Polymers at the Center of Life’s Origins: The Importance of Molecular Processivity

(2008) Robert Stern et al.   CHEMICAL REVIEWS

The Implausibility of Metabolic Cycles on the Prebiotic Earth

(2008) Leslie E Orgel   PLOS BIOLOGY