Epigenetic Clock Acceleration Is Linked to Age at Onset of Parkinson's Disease

Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease

(2021) Dongbing Lai et al.   ANNALS OF NEUROLOGY

Seq-ing out cell types across the isocortex and hippocampal formation

(2021) Guo-li Ming et al.   CELL

DNA methylation age acceleration is associated with ALS age of onset and survival

(2020) Ming Zhang et al.   ACTA NEUROPATHOLOGICA

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

(2020) Julien Bryois et al.   NATURE GENETICS

Age at Onset of Parkinson’s Disease Among Ashkenazi Jewish Patients: Contribution of Environmental Factors, LRRK2 p.G2019S and GBA p.N370S Mutations

(2020) Gilad Yahalom et al.   Journal of Parkinsons Disease

Nonsteroidal Anti‐Inflammatory Use and LRRK2 Parkinson's Disease Penetrance

(2020) Marta San Luciano et al.   MOVEMENT DISORDERS

Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson’s disease

(2020) Brown EE et al.   NEUROBIOLOGY OF AGING

Age at Onset of LRRK2 p. Gly2019Ser Is Related to Environmental and Lifestyle Factors

(2020) Theresa Lüth et al.   MOVEMENT DISORDERS

Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

(2019) Ronald B Postuma et al.   BRAIN

The genetic architecture of Parkinson's disease

(2019) Cornelis Blauwendraat et al.   LANCET NEUROLOGY

Genetic identification of brain cell types underlying schizophrenia

(2018) Nathan G. Skene et al.   NATURE GENETICS

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

(2018) Ming Zhang et al.   BRAIN

Parkinsonism due to A53E α-synuclein gene mutation: Clinical, genetic, epigenetic, and biochemical features

(2018) Marina Picillo et al.   MOVEMENT DISORDERS

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Penetrance estimate of LRRK2 p.G2019S mutation in individuals of non-Ashkenazi Jewish ancestry

(2017) Annie J. Lee et al.   MOVEMENT DISORDERS

Identification of genetic modifiers of age-at-onset for familial Parkinson’s disease

(2016) Erin M. Hill-Burns et al.   HUMAN MOLECULAR GENETICS

Genetic and epigenetic study of ALS-discordant identical twins with double mutations inSOD1andARHGEF28

(2016) Ming Zhang et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study

(2016) Joanne Trinh et al.   LANCET NEUROLOGY

Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients

(2015) Steve Horvath et al.   Aging-US

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Complete pipeline for Infinium® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation

(2012) Nizar Touleimat et al.   Epigenomics

Olfactory dysfunction in LRRK2 G2019S mutation carriers

(2011) R. Saunders-Pullman et al.   NEUROLOGY

The Parkinson Progression Marker Initiative (PPMI)

(2011) Kenneth Marek et al.   PROGRESS IN NEUROBIOLOGY

LRRK2 G2019S in the North African Population: A Review

(2010) Hani T.S. Benamer et al.   EUROPEAN NEUROLOGY

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

(2008) Daniel G Healy et al.   LANCET NEUROLOGY

Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results

(2008) Christopher G. Goetz et al.   MOVEMENT DISORDERS

LRRK2 and Parkin mutations in a family with parkinsonism—Lack of genotype–phenotype correlation

(2008) Connie Marras et al.   NEUROBIOLOGY OF AGING