Development of Fibroblast Activation Protein Inhibitor-Based Dimeric Radiotracers with Improved Tumor Retention and Antitumor Efficacy
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Development of Fibroblast Activation Protein Inhibitor-Based Dimeric Radiotracers with Improved Tumor Retention and Antitumor Efficacy
Authors
Keywords
-
Journal
MOLECULAR PHARMACEUTICS
Volume -, Issue -, Pages -
Publisher
American Chemical Society (ACS)
Online
2022-08-03
DOI
10.1021/acs.molpharmaceut.2c00424
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Fibroblast activation protein-based theranostics in cancer research: A state-of-the-art review
- (2022) Liang Zhao et al. Theranostics
- Equivalent tumor detection for early and late FAPI-46 PET acquisition
- (2021) J. Ferdinandus et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Safety of Fibroblast Activation Protein–Targeted Radionuclide Therapy by a Low-Dose Dosimetric Approach Using 177Lu-FAPI04
- (2021) Serkan Kuyumcu et al. CLINICAL NUCLEAR MEDICINE
- Feasibility and Therapeutic Potential of 177Lu–Fibroblast Activation Protein Inhibitor–46 for Patients With Relapsed or Refractory Cancers
- (2021) Majid Assadi et al. CLINICAL NUCLEAR MEDICINE
- Fibroblast activation protein targeted therapy using [177Lu]FAPI-46 compared with [225Ac]FAPI-46 in a pancreatic cancer model
- (2021) Yuwei Liu et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Synthesis, preclinical evaluation, and a pilot clinical PET imaging study of 68Ga-labeled FAPI dimer
- (2021) Liang Zhao et al. JOURNAL OF NUCLEAR MEDICINE
- Feasibility, Biodistribution and Preliminary Dosimetry in Peptide-Targeted Radionuclide Therapy (PTRT) of Diverse Adenocarcinomas using 177Lu-FAP-2286: First-in-Human Results
- (2021) Richard P Baum et al. JOURNAL OF NUCLEAR MEDICINE
- Initial clinical experience with 90Y-FAPI-46 radioligand therapy for advanced stage solid tumors: a case series of nine patients
- (2021) Justin Ferdinandus et al. JOURNAL OF NUCLEAR MEDICINE
- Fatty acid-conjugated radiopharmaceuticals for fibroblast activation protein-targeted radiotherapy
- (2021) Pu Zhang et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- PET with a 68Ga-labeled FAPI dimer: moving towards theranostics
- (2021) Muhsin H Younis et al. JOURNAL OF NUCLEAR MEDICINE
- Albumin Binder–Conjugated Fibroblast Activation Protein Inhibitor Radiopharmaceuticals for Cancer Therapy
- (2021) Mengxin Xu et al. JOURNAL OF NUCLEAR MEDICINE
- Synthesis and Preliminary Evaluation of 131I-Labeled FAPI Tracers for Cancer Theranostics
- (2021) Huan Ma et al. MOLECULAR PHARMACEUTICS
- Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics
- (2021) Xuejun Wen et al. Theranostics
- First-In-Human Results on the Biodistribution, Pharmacokinetics, and Dosimetry of [177Lu]Lu-DOTA.SA.FAPi and [177Lu]Lu-DOTAGA.(SA.FAPi)2
- (2021) Sanjana Ballal et al. Pharmaceuticals
- Comparison of [68Ga]Ga-DOTA-FAPI-04 and [18F] FDG PET/CT for the diagnosis of primary and metastatic lesions in patients with various types of cancer
- (2020) Haojun Chen et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Imaging Fibroblast Activation Protein Alpha Improves Diagnosis of Metastatic Prostate Cancer with Positron Emission Tomography
- (2020) Hallie M. Hintz et al. CLINICAL CANCER RESEARCH
- Usefulness of [68Ga]Ga-DOTA-FAPI-04 PET/CT in patients presenting with inconclusive [18F]FDG PET/CT findings
- (2020) Haojun Chen et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Imaging of Fibroblast Activation Protein Alpha Expression in a Preclinical Mouse Model of Glioma Using Positron Emission Tomography
- (2020) Darpan N. Pandya et al. MOLECULES
- Prevention and Management of Hormonal Crisis during Theragnosis with LU-DOTA-TATE in Neuroendocrine Tumors. A Systematic Review and Approach Proposal
- (2020) Maria Isabel del Olmo-García et al. Journal of Clinical Medicine
- Peptide Receptor Radionuclide Therapy of Late-stage Neuroendocrine Tumor Patients with Multiple Cycles of 177Lu-DOTA-EB-TATE
- (2020) Qingxing Liu et al. JOURNAL OF NUCLEAR MEDICINE
- Targeted Radionuclide Therapy in Patient-Derived Xenografts Using 177Lu-EB-RGD
- (2020) Liang Zhao et al. MOLECULAR CANCER THERAPEUTICS
- Development of novel FAP-targeted radiotracers with improved tumor retention
- (2019) Anastasia Loktev et al. JOURNAL OF NUCLEAR MEDICINE
- In search of definitions: Cancer-associated fibroblasts and their markers
- (2019) Martin Nurmik et al. INTERNATIONAL JOURNAL OF CANCER
- Theranostics targeting fibroblast activation protein in the tumor stroma: 64Cu and 225Ac labelled FAPI-04 in pancreatic cancer xenograft mouse models
- (2019) Tadashi Watabe et al. JOURNAL OF NUCLEAR MEDICINE
- Radiation dosimetry and biodistribution of 68Ga-FAPI-46 PET imaging in cancer patients
- (2019) Catherine Meyer et al. JOURNAL OF NUCLEAR MEDICINE
- Development of quinoline based theranostic ligands for the targeting of fibroblast activation protein
- (2018) Thomas Lindner et al. JOURNAL OF NUCLEAR MEDICINE
- A new method for tumor imaging by targeting cancer associated fibroblasts
- (2018) Anastasia Loktev et al. JOURNAL OF NUCLEAR MEDICINE
- First-in-human study of 177Lu-EB-PSMA-617 in patients with metastatic castration-resistant prostate cancer
- (2018) Jie Zang et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- 177 Lu-PSMA Radioligand Therapy for Prostate Cancer
- (2017) Wolfgang P. Fendler et al. JOURNAL OF NUCLEAR MEDICINE
- Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases
- (2017) Arnaud Blomme et al. ONCOGENE
- Novel “Add-On” Molecule Based on Evans Blue Confers Superior Pharmacokinetics and Transforms Drugs to Theranostic Agents
- (2016) Haojun Chen et al. JOURNAL OF NUCLEAR MEDICINE
- Radiolabeled Cyclic RGD Peptide Bioconjugates as Radiotracers Targeting Multiple Integrins
- (2015) Shuang Liu BIOCONJUGATE CHEMISTRY
- Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)
- (2014) Koen Jansen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
- (2013) C. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
- (2011) Yoko S DeRose et al. NATURE MEDICINE
- Clustering and Internalization of Integrin αvβ3 With a Tetrameric RGD-synthetic Peptide
- (2009) Sancey Lucie et al. MOLECULAR THERAPY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started