Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation

Mitochondrial NADP(H) generation is essential for proline biosynthesis

(2021) Jiajun Zhu et al.   SCIENCE

Web-Based Survival Analysis Tool Tailored for Medical Research (KMplot): Development and Implementation

(2021) András Lánczky et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

NADPH—The Forgotten Reducing Equivalent

(2021) Navdeep S. Chandel   Cold Spring Harbor Perspectives in Biology

NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma

(2021) Tanya Schild et al.   Cell Reports

Protein kinase C activates NAD kinase in human neutrophils

(2020) Razieh Rabani et al.   FREE RADICAL BIOLOGY AND MEDICINE

ATSAS 3.0: expanded functionality and new tools for small-angle scattering data analysis

(2020) Karen Manalastas-Cantos et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase

(2019) Gerta Hoxhaj et al.   SCIENCE

Metabolic heterogeneity confers differences in melanoma metastatic potential

(2019) Alpaslan Tasdogan et al.   NATURE

Clinical heterogeneity of mitochondrial NAD kinase deficiency caused by a NADK2 start loss variant

(2018) Daniel J. Pomerantz et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications

(2018) Chris Carrico et al.   Cell Metabolism

Deficiency of the Mitochondrial NAD Kinase Causes Stress-Induced Hepatic Steatosis in Mice

(2018) Kezhong Zhang et al.   GASTROENTEROLOGY

Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites

(2017) Walter W Chen et al.   Nature Protocols

Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

(2016) Walter W. Chen et al.   CELL

Post-translational modifications in mitochondria: protein signaling in the powerhouse

(2016) Amanda R. Stram et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

Significance of Ser-188 in human mitochondrial NAD kinase as determined by phosphomimetic and phosphoresistant amino-acid substitutions

(2015) Yutaka Kawabata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acetyl-ed question in mitochondrial biology?

(2015) D. B. Lombard et al.   EMBO JOURNAL

NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms

(2015) Nick R. Love et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia

(2014) Sander M. Houten et al.   HUMAN MOLECULAR GENETICS

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

(2014) Caroline A. Lewis et al.   MOLECULAR CELL

Quantitative flux analysis reveals folate-dependent NADPH production

(2014) Jing Fan et al.   NATURE

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Automatic processing of macromolecular crystallography X-ray diffraction data at the ESRF

(2013) Stéphanie Monaco et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Identification and characterization of a human mitochondrial NAD kinase

(2012) Kazuto Ohashi et al.   Nature Communications

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Structural Determinants of Discrimination of NAD+from NADH in Yeast Mitochondrial NADH Kinase Pos5

(2011) Takuya Ando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Empirical Scoring Functions for Advanced Protein−Ligand Docking with PLANTS

(2009) Oliver Korb et al.   Journal of Chemical Information and Modeling