Integration of light and temperature sensing by liquid-liquid phase separation of phytochrome B

Plant phytochrome B is an asymmetric dimer with unique signalling potential

(2022) Hua Li et al.   NATURE

Differing biophysical properties underpin the unique signaling potentials within the plant phytochrome photoreceptor families

(2021) E. Sethe Burgie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions

(2020) Jeong-Mo Choi et al.   Annual Review of Biophysics

Increasing ambient temperature progressively disassembles Arabidopsis phytochrome B from individual photobodies with distinct thermostabilities

(2020) Joseph Hahm et al.   Nature Communications

A quantitative inventory of yeast P body proteins reveals principles of composition and specificity

(2020) Wenmin Xing et al.   eLife

Emerging Roles for Phase Separation in Plants

(2020) Ryan J. Emenecker et al.   DEVELOPMENTAL CELL

A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis

(2020) Jae-Hoon Jung et al.   NATURE

Thermal stress accelerates Arabidopsis thaliana mutation rate

(2020) Eric J. Belfield et al.   GENOME RESEARCH

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Thermomorphogenesis

(2019) Jorge J. Casal et al.   Annual Review of Plant Biology

Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes

(2019) Xiaofeng Fang et al.   NATURE

PCH1 regulates light, temperature, and circadian signaling as a structural component of phytochrome B-photobodies in Arabidopsis

(2019) He Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential phosphorylation of the N‐terminal extension regulates phytochrome B signaling

(2019) András Viczián et al.   NEW PHYTOLOGIST

Molecular mechanisms underlying phytochrome-controlled morphogenesis in plants

(2019) Martina Legris et al.   Nature Communications

Thermal Reversion of Plant Phytochromes

(2019) Cornelia Klose et al.   Molecular Plant

RGG/RG Motif Regions in RNA Binding and Phase Separation

(2018) P. Andrew Chong et al.   JOURNAL OF MOLECULAR BIOLOGY

IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

(2018) Bálint Mészáros et al.   NUCLEIC ACIDS RESEARCH

Phytochrome B Requires PIF Degradation and Sequestration to Induce Light Responses across a Wide Range of Light Conditions

(2018) Eunae Park et al.   PLANT CELL

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Light and temperature cues: multitasking receptors and transcriptional integrators

(2017) Jorge J. Casal et al.   NEW PHYTOLOGIST

New insights into the mechanisms of phytochrome-cryptochrome coaction

(2017) Qin Wang et al.   NEW PHYTOLOGIST

PPKs mediate direct signal transfer from phytochrome photoreceptors to transcription factor PIF3

(2017) Weimin Ni et al.   Nature Communications

Mechanism of early light signaling by the carboxy-terminal output module of Arabidopsis phytochrome B

(2017) Yongjian Qiu et al.   Nature Communications

Molecular basis for blue light-dependent phosphorylation of Arabidopsis cryptochrome 2

(2017) Qing Liu et al.   Nature Communications

Photosensing and Thermosensing by Phytochrome B Require Both Proximal and Distal Allosteric Features within the Dimeric Photoreceptor

(2017) E. Sethe Burgie et al.   Scientific Reports

Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light

(2016) Ullas V. Pedmale et al.   CELL

Mechanisms and Consequences of Macromolecular Phase Separation

(2016) Louis-Philippe Bergeron-Sandoval et al.   CELL

Liquid–liquid phase separation in cellular signaling systems

(2016) P Andrew Chong et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Red Light Receptor Phytochrome B Directly Enhances Substrate-E3 Ligase Interactions to Attenuate Ethylene Responses

(2016) Hui Shi et al.   DEVELOPMENTAL CELL

Light-sensing phytochromes feel the heat

(2016) Karen J. Halliday et al.   SCIENCE

Phytochrome B integrates light and temperature signals in Arabidopsis

(2016) Martina Legris et al.   SCIENCE

Phytochromes function as thermosensors in Arabidopsis

(2016) Jae-Hoon Jung et al.   SCIENCE

Mapping light-driven conformational changes within the photosensory module of plant phytochrome B

(2016) Silke von Horsten et al.   Scientific Reports

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Red Light-Regulated Reversible Nuclear Localization of Proteins in Mammalian Cells and Zebrafish

(2015) Hannes M. Beyer et al.   ACS Synthetic Biology

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Interaction of light and temperature signalling

(2014) Keara A. Franklin et al.   JOURNAL OF EXPERIMENTAL BOTANY

Phytochrome B Nuclear Bodies Respond to the Low Red to Far-Red Ratio and to the Reduced Irradiance of Canopy Shade in Arabidopsis

(2014) S. A. Trupkin et al.   PLANT PHYSIOLOGY

Crystal structure of the photosensing module from a red/far-red light-absorbing plant phytochrome

(2014) E. S. Burgie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Phytochrome B Inhibits Light-Induced Signaling via Accelerated Dark Reversion in Arabidopsis

(2013) M. Medzihradszky et al.   PLANT CELL

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Blue Light-Dependent Interaction of CRY2 with SPA1 Regulates COP1 activity and Floral Initiation in Arabidopsis

(2011) Zecheng Zuo et al.   CURRENT BIOLOGY

Photobodies in Light Signaling

(2011) E. K. Van Buskirk et al.   PLANT PHYSIOLOGY

Arabidopsis HEMERA/pTAC12 Initiates Photomorphogenesis by Phytochromes

(2010) Meng Chen et al.   CELL

An Integrative Model for Phytochrome B Mediated Photomorphogenesis: From Protein Dynamics to Physiology

(2010) Julia Rausenberger et al.   PLoS One

High Temperature-Mediated Adaptations in Plant Architecture Require the bHLH Transcription Factor PIF4

(2009) Maria A. Koini et al.   CURRENT BIOLOGY

Phytochrome functions in Arabidopsis development

(2009) K. A. Franklin et al.   JOURNAL OF EXPERIMENTAL BOTANY

Cryptochromes, Phytochromes, and COP1 Regulate Light-Controlled Stomatal Development in Arabidopsis

(2009) C.-Y. Kang et al.   PLANT CELL

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

A Light-Independent Allele of Phytochrome B Faithfully Recapitulates Photomorphogenic Transcriptional Networks

(2008) Wei Hu et al.   Molecular Plant

The Arabidopsis Phytochrome-Interacting Factor PIF7, Together with PIF3 and PIF4, Regulates Responses to Prolonged Red Light by Modulating phyB Levels

(2008) P. Leivar et al.   PLANT CELL