The Complexity of alpha E beta 7 Blockade in Inflammatory Bowel Diseases

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis

(2016) Gaik W. Tew et al.   GASTROENTEROLOGY

Blockade of αEβ7 integrin suppresses accumulation of CD8+and Th9 lymphocytes from patients with IBD in the inflamed gut in vivo

(2016) Sebastian Zundler et al.   GUT

Gut Inflammation in Mice Triggers Proliferation and Function of Mucosal Foxp3+Regulatory T Cells but Impairs Their Conversion from CD4+T Cells

(2016) Gilles Boschetti et al.   Journal of Crohns & Colitis

Classical dendritic cells are required for dietary antigen–mediated induction of peripheral Treg cells and tolerance

(2016) Daria Esterházy et al.   NATURE IMMUNOLOGY

Reduced numbers of mucosal DRintmacrophages and increased numbers of CD103+dendritic cells during anti-TNF-α treatment in patients with Crohn’s disease

(2016) Anders Dige et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Evidence for Resident Memory T Cells in Rasmussen Encephalitis

(2016) Geoffrey C. Owens et al.   Frontiers in Immunology

Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria

(2015) Jochem H. Bernink et al.   IMMUNITY

β7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon

(2015) A Schippers et al.   Mucosal Immunology

The emerging role of resident memory T cells in protective immunity and inflammatory disease

(2015) Chang Ook Park et al.   NATURE MEDICINE

Hematopoietic mobilization: Potential biomarker of response to natalizumab in multiple sclerosis

(2015) M. Mattoscio et al.   NEUROLOGY

Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn's Disease

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

(2015) Rei Watanabe et al.   Science Translational Medicine

Review article: anti-adhesion therapies for inflammatory bowel disease

(2014) T. Lobatón et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Naive T Cells in the Gut of Newly Diagnosed, Untreated Adult Patients with Inflammatory Bowel Disease

(2014) Carmen S. Horjus Talabur Horje et al.   INFLAMMATORY BOWEL DISEASES

Human Gut Dendritic Cells Drive Aberrant Gut-specific T-cell Responses in Ulcerative Colitis, Characterized by Increased IL-4 Production and Loss of IL-22 and IFNγ

(2014) Elizabeth R. Mann et al.   INFLAMMATORY BOWEL DISEASES

A CD8+/CD103high T Cell Subset Regulates TNF-Mediated Chronic Murine Ileitis

(2014) J. Ho et al.   JOURNAL OF IMMUNOLOGY

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

(2014) Séverine Vermeire et al.   LANCET

Vedolizumab for inflammatory bowel disease: Changing the game, or more of the same?

(2014) Tim Raine   United European Gastroenterology Journal

β7 integrins are required to give rise to intestinal mononuclear phagocytes with tolerogenic potential

(2013) Eduardo J Villablanca et al.   GUT

α4β7integrin: beyond T cell trafficking

(2013) Sarah L Kempster et al.   GUT

SMAD regulatory networks construct a balanced immune system

(2013) Nidhi Malhotra et al.   IMMUNOLOGY

Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice

(2013) Payal B Watchmaker et al.   NATURE IMMUNOLOGY

Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis

(2013) Brian G. Feagan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phenotypic and functional characteristic of a newly identified CD8+Foxp3−CD103+ regulatory T cells

(2013) Ya Liu et al.   Journal of Molecular Cell Biology

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

(2012) Paul J Rutgeerts et al.   GUT

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Accumulation of CCR4+ CTLA-4hi FOXP3+CD25hi Regulatory T Cells in Colon Adenocarcinomas Correlate to Reduced Activation of Conventional T Cells

(2012) Helena Svensson et al.   PLoS One

Mucosal Gene Expression of Cell Adhesion Molecules, Chemokines and Chemokine Receptors in Patients With Inflammatory Bowel Disease Before and After Infliximab Treatment

(2011) Ingrid Arijs et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes

(2011) EG Stefanich et al.   BRITISH JOURNAL OF PHARMACOLOGY

Flt3 ligand expands CD103+dendritic cells and FoxP3+T regulatory cells, and attenuates Crohn's-like murine ileitis

(2011) Colm B Collins et al.   GUT

Assessing the Role of CD103 in Immunity to an Intestinal Helminth Parasite

(2011) Sarah C. Mullaly et al.   PLoS One

E-Cadherin Marks a Subset of Inflammatory Dendritic Cells that Promote T Cell-Mediated Colitis

(2010) Karima R.R. Siddiqui et al.   IMMUNITY

An Anti-CD103 Immunotoxin Promotes Long-Term Survival of Pancreatic Islet Allografts

(2009) L. Zhang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Integrins

(2009) Malgorzata Barczyk et al.   CELL AND TISSUE RESEARCH

Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells

(2009) I D Iliev et al.   GUT

The Binding Specificity and Selective Antagonism of Vedolizumab, an Anti- 4 7 Integrin Therapeutic Antibody in Development for Inflammatory Bowel Diseases

(2009) D. Soler et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Small intestinal CD103+dendritic cells display unique functional properties that are conserved between mice and humans

(2008) Elin Jaensson et al.   JOURNAL OF EXPERIMENTAL MEDICINE