Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinoma

Hallmarks of Cancer: New Dimensions

(2022) Douglas Hanahan   Cancer Discovery

A pro-carcinogenic colon microbe promotes breast tumorigenesis and metastatic progression and concomitantly activates Notch and βcatenin axes

(2021) Sheetal Parida et al.   Cancer Discovery

Microbiome and cancer

(2021) Nyssa Cullin et al.   CANCER CELL

Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer

(2021) Maik Luu et al.   Nature Communications

Specific microbiota enhances intestinal IgA levels by inducing TGF‐β in T follicular helper cells of Peyer's patches in mice

(2020) Alexander Beller et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Predictable modulation of cancer treatment outcomes by the gut microbiota

(2020) Yoshitaro Heshiki et al.   Microbiome

The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients?

(2020) Fabien Magne et al.   Nutrients

Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer

(2020) Winnie Fong et al.   ONCOGENE

Cancer-protective effect of a synbiotic combination between Lactobacillus gasseri 505 and a Cudrania tricuspidata leaf extract on colitis-associated colorectal cancer

(2020) Nam Su Oh et al.   Gut Microbes

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

(2019) Maik Luu et al.   Nature Communications

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

(2019) Takeshi Tanoue et al.   NATURE

The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer?

(2019) Priyanka Bhateja et al.   Cancers

Distinct Microbial Signatures Associated With Different Breast Cancer Types

(2018) Sagarika Banerjee et al.   Frontiers in Microbiology

Intestinal Microbiota at Engraftment Influence Acute Graft-Versus-Host Disease via the Treg/Th17 Balance in Allo-HSCT Recipients

(2018) Lijie Han et al.   Frontiers in Immunology

Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice

(2018) Fengwei Pan et al.   Microbiome

The Complex Interplay between Chronic Inflammation, the Microbiome, and Cancer: Understanding Disease Progression and What We Can Do to Prevent It

(2018) Heather Armstrong et al.   Cancers

Inhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer

(2018) Ann Hanna et al.   OncoImmunology

Impact of chemotherapy on gastrointestinal functions and the enteric nervous system

(2017) Jonathan Escalante et al.   MATURITAS

Intestinal Proportion of Blautia sp. is Associated with Clinical Stage and Histoprognostic Grade in Patients with Early-Stage Breast Cancer

(2017) Trang H. Luu et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Intestinal Barrier Interactions with Specialized CD8 T Cells

(2017) Špela Konjar et al.   Frontiers in Immunology

Immunological and Clinical Effect of Diet Modulation of the Gut Microbiome in Multiple Sclerosis Patients: A Pilot Study

(2017) Marina Saresella et al.   Frontiers in Immunology

Resetting microbiota byLactobacillus reuteriinhibits T reg deficiency–induced autoimmunity via adenosine A2Areceptors

(2016) Baokun He et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mucosal adherent bacterial dysbiosis in patients with colorectal adenomas

(2016) Yingying Lu et al.   Scientific Reports

Evidence for a link between gut microbiota and hypertension in the Dahl rat

(2015) Blair Mell et al.   PHYSIOLOGICAL GENOMICS

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

(2015) A. Sivan et al.   SCIENCE

Ablation of Tumor Necrosis Factor Is Associated with Decreased Inflammation and Alterations of the Microbiota in a Mouse Model of Inflammatory Bowel Disease

(2015) Yava L. Jones-Hall et al.   PLoS One

Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

(2015) Sachiko Miyake et al.   PLoS One

Microbiome, Inflammation, and Cancer

(2014) Ralph Francescone et al.   CANCER JOURNAL

Anti-Colitic Effects of Kanjangs (Fermented Soy Sauce and Sesame Sauce) in Dextran Sulfate Sodium-Induced Colitis in Mice

(2014) Jia-Le Song et al.   JOURNAL OF MEDICINAL FOOD

Development of a Dual-Index Sequencing Strategy and Curation Pipeline for Analyzing Amplicon Sequence Data on the MiSeq Illumina Sequencing Platform

(2013) James J. Kozich et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Unraveling the therapeutic potential of the Hedgehog pathway in cancer

(2013) Dereck Amakye et al.   NATURE MEDICINE

Lactobacillus reuteri DSM 17938 Changes the Frequency of Foxp3+ Regulatory T Cells in the Intestine and Mesenteric Lymph Node in Experimental Necrotizing Enterocolitis

(2013) Yuying Liu et al.   PLoS One

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

Reciprocal interactions of the intestinal microbiota and immune system

(2012) Craig L. Maynard et al.   NATURE

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Immunomodulatory mechanisms of lactobacilli

(2011) Jerry M Wells   Microbial Cell Factories

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Perspective: Alpha-Bugs, Their Microbial Partners, and the Link to Colon Cancer

(2010) Cynthia L. Sears et al.   JOURNAL OF INFECTIOUS DISEASES

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

(2010) J. G. Caporaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE