Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function
Authors
Keywords
-
Journal
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Volume 80, Issue 7, Pages 653-662
Publisher
Elsevier BV
Online
2022-08-09
DOI
10.1016/j.jacc.2022.05.041
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- PCSK9 genetic variants and cognitive abilities: a large-scale Mendelian randomization study
- (2021) Donald Lyall et al. Archives of Medical Science
- Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
- (2021) Ruth Chia et al. NATURE GENETICS
- Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development
- (2021) Michael V. Holmes et al. Nature Reviews Cardiology
- HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis
- (2021) Sally A. Abuelezz et al. LIFE SCIENCES
- Cardiovascular Disease Risk–Based Statin Utilization and Associated Outcomes in a Primary Prevention Cohort: Insights From a Large Health Care Network
- (2021) Anum Saeed et al. Circulation-Cardiovascular Quality and Outcomes
- Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol
- (2020) Kausik K. Ray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inclisiran for the Treatment of Heterozygous Familial Hypercholesterolemia
- (2020) Frederick J. Raal et al. NEW ENGLAND JOURNAL OF MEDICINE
- The genetic architecture of the human cerebral cortex
- (2020) Katrina L. Grasby et al. SCIENCE
- Statins and PCSK9 inhibitors: A new lipid-lowering therapy
- (2020) Enrique Gallego-Colon et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Genetic drug target validation using Mendelian randomisation
- (2020) Amand F. Schmidt et al. Nature Communications
- Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in the Brain and Relevance for Neuropsychiatric Disorders
- (2020) Emma M. O’Connell et al. Frontiers in Neuroscience
- Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study
- (2020) Daniel B. Rosoff et al. PLOS MEDICINE
- Scientists rise up against statistical significance
- (2019) Valentin Amrhein et al. NATURE
- Efficacy and safety of alirocumab and evolocumab: a systematic review and meta-analysis of randomized controlled trials
- (2019) Paul Guedeney et al. EUROPEAN HEART JOURNAL
- Effects of Statins on Memory, Cognition, and Brain Volume in the Elderly
- (2019) Katherine Samaras et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Lipid lowering and Alzheimer disease risk: A mendelian randomization study
- (2019) Dylan M. Williams et al. ANNALS OF NEUROLOGY
- Genetic study of multimodal imaging Alzheimer’s disease progression score implicates novel loci
- (2018) Marzia A Scelsi et al. BRAIN
- PCSK9
- (2018) Michael D. Shapiro et al. CIRCULATION RESEARCH
- PCSK9 and neurocognitive function: Should it be still an issue after FOURIER and EBBINGHAUS results?
- (2018) Massimo R. Mannarino et al. Journal of Clinical Lipidology
- Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
- (2018) James J. Lee et al. NATURE GENETICS
- Underutilization of Statin Therapy for Secondary Prevention of Cardiovascular Disease Among Older Adults
- (2018) Shirley Musich et al. Population Health Management
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
- (2018) Gail Davies et al. Nature Communications
- Use of statins and the risk of dementia and mild cognitive impairment: A systematic review and meta-analysis
- (2018) Che-Sheng Chu et al. Scientific Reports
- Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
- (2018) Neil M Davies et al. BMJ-British Medical Journal
- Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
- (2018) Neil M Davies et al. BMJ-British Medical Journal
- The MR-Base platform supports systematic causal inference across the human phenome
- (2018) Gibran Hemani et al. eLife
- The role of statins in both cognitive impairment and protection against dementia: a tale of two mechanisms
- (2018) Bob G. Schultz et al. Translational Neurodegeneration
- Nonstatin Therapy for Dyslipidemia
- (2018) Haitham M. Ahmed et al. CIRCULATION RESEARCH
- Inclisiran Lowers LDL-C and PCSK9 Irrespective of Diabetes Status: The ORION-1 Randomized Clinical Trial
- (2018) Lawrence A. Leiter et al. DIABETES CARE
- Lipid-Lowering Drug Effects Beyond the Cardiovascular System: Relevance for Neuropsychiatric Disorders
- (2018) Falk W Lohoff INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- PCSK9 inhibitors: clinical evidence and implementation
- (2018) Marc S. Sabatine Nature Reviews Cardiology
- Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome
- (2018) Gregory G. Schwartz et al. NEW ENGLAND JOURNAL OF MEDICINE
- MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data
- (2017) Olena O Yavorska et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- PCSK9 Inhibitors
- (2017) Mark A. Hlatky et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder
- (2017) F W Lohoff et al. MOLECULAR PSYCHIATRY
- A genome-wide association study for extremely high intelligence
- (2017) D Zabaneh et al. MOLECULAR PSYCHIATRY
- Nine paths to PCSK9 inhibition
- (2017) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Cognitive Function in a Randomized Trial of Evolocumab
- (2017) Robert P. Giugliano et al. NEW ENGLAND JOURNAL OF MEDICINE
- Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
- (2017) Marc S. Sabatine et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events
- (2015) Jennifer G. Robinson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Demographic and Epidemiologic Drivers of Global Cardiovascular Mortality
- (2015) Gregory A. Roth et al. NEW ENGLAND JOURNAL OF MEDICINE
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
- (2014) Paul M. Thompson et al. Brain Imaging and Behavior
- Cognitive Effects of Statin Medications
- (2014) Brendan J. Kelley et al. CNS DRUGS
- Statins and Cognition: A Systematic Review and Meta-analysis of Short- and Long-term Cognitive Effects
- (2013) Kristopher J. Swiger et al. MAYO CLINIC PROCEEDINGS
- Discovery and refinement of loci associated with lipid levels
- (2013) Cristen J Willer et al. NATURE GENETICS
- Statins in the primary prevention of cardiovascular disease
- (2013) Željko Reiner Nature Reviews Cardiology
- Low-Density Lipoprotein Cholesterol–Lowering Effects of AMG 145, a Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 Serine Protease in Patients With Heterozygous Familial Hypercholesterolemia
- (2012) Frederick Raal et al. CIRCULATION
- Alzheimer's Disease Neuroimaging Initiative (ADNI): Clinical characterization
- (2009) R. C. Petersen et al. NEUROLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started