Review
Medicine, General & Internal
Maddalena De Bernardo, Livio Vitiello, Martina De Luca, Aniello La Marca, Nicola Rosa
Summary: This review provides an overview of the use of optic nerve ultrasound evaluation to detect intracranial pressure changes during surgical procedures, and discusses the limitations of the B-scan technique. The results show that ocular ultrasonography is a valuable diagnostic tool in the surgical setting for indirectly assessing intracranial pressure.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
David Berhanu, Joana Cardoso Ferreira, Luis Abegao Pinto, Diana Aguiar de Sousa, Lia Lucas Neto, Joana Tavares Ferreira
Summary: Ultrasonographic optic nerve sheath diameter (ONSD) demonstrates high diagnostic accuracy for increased intracranial pressure (IICP), with both high sensitivity and specificity. Larger cut-off values significantly increase specificity without compromising sensitivity. Ultrasonographic ONSD can serve as a screening tool for IICP, providing an estimate of when invasive methods are needed.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2023)
Article
Oncology
Daniel Feucht, Susanne R. Kerscher, Christer Ruff, Martin U. Schuhmann, Constantin Roder, Julian Zipfel
Summary: Assessing GBM patients with MRI revealed the potential of ONSD to identify high ICP. Preoperative increase in ONSD was associated with edema, while postoperatively ONSD decreased until 3 months after surgery and increased again at 12 months. Further prospective data collection is warranted for validation.
Review
Medicine, General & Internal
Maddalena De Bernardo, Livio Vitiello, Ilaria De Pascale, Luigi Capasso, Palmiro Cornetta, Nicola Rosa
Summary: Ocular ultrasonography is a reliable technique for diagnosing idiopathic intracranial hypertension in a fast and non-invasive way, allowing for the assessment of optic nerve indices.
FRONTIERS IN MEDICINE
(2022)
Article
Surgery
Kathleen E. Singer, Taylor E. Wallen, Timothy Jalbert, Devin Wakefield, Anthony Spuzzillo, Sameer Sharma, Ryan Earnest, Victor Heh, Brandon Foreman, Michael D. Goodman
Summary: The study found that optic nerve sheath diameter (ONSD) and pupillometry may be used as supplementary screening tools for diagnosing severe TBI, while transcranial Doppler ultrasound (TCD) could be used to estimate and monitor intracranial pressure (ICP) in patients with severe TBI.
JOURNAL OF SURGICAL RESEARCH
(2021)
Review
Anesthesiology
Amr Sallam, Ahmed Abdelaal Ahmed Mahmoud M. Alkhatip, Mohamed Gomaa Kamel, Mohamed Khaled Hamza, Hany Mahmoud Yassin, Hisham Hosny, Mohamed Younis, Eslam Ramadan, Haytham Zien Algameel, Mohamed Abdelhaq, Mohamed Abdelkader, Kerry E. Mills, Hassan Mohamed
Summary: The study found that ultrasonographic optic nerve sheath diameter (US ONSD) has high diagnostic accuracy for intracranial hypertension (ICH), while the accuracy of MRI and CT varied. Using multiple noninvasive methods is more reliable than depending on a single method.
ANESTHESIA AND ANALGESIA
(2021)
Article
Clinical Neurology
Hans-Christian Hansen, Stine Solveig Helmke, Knut Helmke
Summary: This study assessed the time course and stability of optic nerve sheath (ONS) widening using in vitro experiments. The results showed that ONS dilation starts rapidly after pressure exposure and follows a predictable time course over 3-4 minutes. These findings are important for understanding intracranial pressure monitoring and diagnosis.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2022)
Article
Behavioral Sciences
Tao Chang, Xigang Yan, Chao Zhao, Yufu Zhang, Bao Wang, Li Gao
Summary: The study investigated the relationship between ONSD or PI and ICP in TBI patients, finding a correlation between ONSD and ICP, with a stronger correlation when ONSD >= 5 mm. There was also a strong correlation between PI and ICP, especially on days 6 and 7 after surgery. A combination of ONSD >= 5 mm and PI >= 1.2 could more accurately predict elevated ICP.
BRAIN AND BEHAVIOR
(2021)
Review
Anesthesiology
M. Dinsmore, L. Venkatraghavan
Summary: The use of point-of-care ultrasound has significantly increased over the past two decades and has become a non-invasive bedside modality for rapid diagnosis and management of patients. Brain ultrasound has been widely used in assessing cerebral blood flow, hemodynamics, and structural pathology.
Review
Clinical Neurology
Jeffrey R. Vitt, Nicholas E. Loper, Shraddha Mainali
Summary: Given the complexity of cerebral pathology in patients with acute brain injury, various neuromonitoring strategies have been developed to better appreciate physiologic relationships and potentially harmful derangements. There is ample evidence that bundling several neuromonitoring devices, termed multimodal monitoring, is more beneficial compared to monitoring individual parameters as each may capture different and complementary aspects of cerebral physiology to provide a comprehensive picture that can help guide management.
FRONTIERS IN NEUROLOGY
(2023)
Article
Medicine, General & Internal
Seung Hyen Lee, Tae-Woo Kim, Eun Ji Lee, Hyunkyung Kil
Summary: This study found that the optic nerve sheath diameter (ONSD) in normal-tension glaucoma (NTG) patients was smaller than in healthy individuals, and there was a negative correlation between ONSD and the curvature index of the lamina cribrosa (LC). These results suggest that cerebrospinal fluid pressure, which is indirectly predicted by ONSD, may affect the morphology of the LC and play a role in the pathogenesis of glaucoma.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Sung Ho Kwon, Sang Hoon Oh, Jinhee Jang, Soo Hyun Kim, Kyu Nam Park, Chun Song Youn, Han Joon Kim, Jee Yong Lim, Hyo Joon Kim, Hyo Jin Bang
Summary: We analyzed the prognostic performance of optic nerve sheath diameter (ONSD) measured on thin-slice brain CT images taken after cardiac arrest. Compared to routine-slice images, thin-slice images showed better prognostic performance. Combining the maximal ONSD and gray-to-white matter ratio (GWR) improved the prediction of poor neurological outcome.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Pediatrics
Didar Arslan, Dincer Yildizdas, Ozden Ozgur Horoz, Nagehan Aslan, Faruk Incecik
Summary: The study demonstrated that ONSD measurements were helpful in children with increased ICP and reflected the increase in ICP. However, there was no correlation between ONSD and NIRS monitoring. Further studies focusing on the use of ONSD and NIRS in monitoring increased ICP are needed.
ITALIAN JOURNAL OF PEDIATRICS
(2021)
Article
Clinical Neurology
Sha Zhu, Chao Cheng, Dianjiang Zhao, Yuanli Zhao, Xianzeng Liu, Jun Zhang
Summary: Measurements of optic nerve sheath diameter and the ONSD/ETD ratio using unenhanced computed tomography can predict the prognosis of comatose patients with supratentorial lesions. The ONSD/ETD ratio may be more valuable than ONSD alone in predicting the prognosis of these patients.
Article
Clinical Neurology
Fatma Selin Kaya, Ersoy Bayram, Ercan Inci
Summary: The purpose of this study was to investigate the optic nerve's elastic properties and optic nerve sheath diameter in patients with IIH compared to healthy individuals using shear-wave elastography. The results showed that patients with IIH had higher optic nerve stiffness and larger optic nerve sheath diameter than healthy volunteers. However, there was no correlation between disease duration and SWE-based stiffness measurement of the optic nerve.
NEUROLOGICAL SCIENCES
(2021)
Review
Clinical Neurology
Benjamin Claytor, Sung-Min Cho, Yuebing Li
Summary: Myasthenic crisis (MC) is a life-threatening manifestation of myasthenia gravis (MG) characterized by respiratory insufficiency. It occurs in 15%-20% of MG patients, usually within the first 2 to 3 years of the disease. The majority of MC cases have specific triggers, with respiratory infections being the most common. Immediate treatment focuses on airway management and addressing triggers. Plasmapheresis is preferred over intravenous immune globulin for MC treatment.
Review
Critical Care Medicine
Denise Battaglini, Elisa Gouvea Bogossian, Pasquale Anania, Lavienraj Premraj, Sung-Min Cho, Fabio Silvio Taccone, Mypinder Sekhon, Chiara Robba
Summary: Cardiac arrest is a sudden event that often leads to brain injury and high mortality rates. Brain tissue oxygenation (PbtO(2)) is a tool used to monitor brain oxygen levels, but its effectiveness is still unclear. A systematic review was conducted to understand the role of PbtO(2) in monitoring brain oxygenation in patients with cardiac arrest and the impact of targeted PbtO(2) therapy on outcomes.
NEUROCRITICAL CARE
(2023)
Review
Critical Care Medicine
Denise Battaglini, Silvia De Rosa, Daniel Agustin Godoy
Summary: Organ crosstalk is a complex form of communication between distal organs mediated by cellular, soluble, and neurohormonal actions. The communication involves the central nervous system, peripheral organs, and various physiological systems. Acute brain injury can lead to neuroinflammation and neurodegeneration, resulting in multiorgan inflammation and dysfunction. Organ crosstalk is gaining popularity, and this review provides an update on the crosstalk between the nervous system and systemic organs after acute brain injury. Future research may help target this pathophysiological process to prevent multiorgan dysfunction in critically ill patients with brain injury.
NEUROCRITICAL CARE
(2023)
Correction
Critical Care Medicine
Denise Battaglini, Silvia De Rosa, Daniel Agustin Godoy
NEUROCRITICAL CARE
(2023)
Article
Cardiac & Cardiovascular Systems
Hayato Taniguchi, Indrek Ratsep, Silver Heinsar, Keibun Liu, Marcela Cespedes, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser, Jeffrey P. Jacobs, Giles J. Peek
Summary: Iliopsoas haematoma (IPH) is a rare bleeding complication during extracorporeal membrane oxygenation (ECMO) with unclear incidence and risk factors. This study used an international multi-centre cohort registry and found an overall incidence rate of 0.64% for IPH in COVID-19 ECMO patients, with comparable rates between countries. The IPH group had a higher mortality rate (71.4%) compared to the non-IPH group. Increased awareness about IPH occurrence is important due to its high fatality rate.
Review
Cardiac & Cardiovascular Systems
Jeffrey Javidfar, Akram M. Zaaqoq, Ahmed Labib, Adrian G. Barnett, J. W. Awori Hayanga, Greg Eschun, Michael H. Yamashita, Jeffrey P. Jacobs, Silver Heinsar, Jacky Y. Suen, John F. Fraser, Gianluigi Li Bassi, Rakesh C. Arora, Giles J. Peek
Summary: Obesity is linked to a worse prognosis in COVID-19 patients with ARDS. It remains unclear how morbid obesity directly affects patients treated with V-V ECMO.
Article
Engineering, Biomedical
Anna Peeler, Patricia M. Davidson, Kelly T. Gleason, R. Scott Stephens, Betty Ferrell, Bo Soo Kim, Sung-Min Cho
Summary: This study investigated the application of palliative care (PC) in patients on extracorporeal membrane oxygenation (ECMO). The findings showed that PC is underused in this population, despite its important role in improving patients' quality of life.
Article
Engineering, Biomedical
Henry Shu, Sung-min Cho, Andrew Harris, Meghana L. Jami, Benjamin J. Shou, Matthew M. Griffee, Akram J. Zaaqoq, Christopher Wilcox, Marc Anders, Peter Rycus, Glenn Whitman, Bo Soo Kim, Babar Shafiq
Summary: The study aimed to investigate whether fasciotomy is associated with increased mortality in patients with acute compartment syndrome (ACS) on extracorporeal cardiopulmonary resuscitation (ECPR). The retrospective study analyzed data from adult ECPR patients diagnosed with ACS between 2013 and 2021. The results showed no significant difference in mortality between ACS patients with and without fasciotomy. Body mass index (BMI) and 24-hour mean blood pressure were identified as independent risk factors for mortality. Prospective studies are needed to confirm these findings and guide surgical decision-making for ACS patients after ECPR.
Article
Critical Care Medicine
Merry Huang, Aron Gedansky, Catherine E. Hassett, Aaron Shoskes, Abhijit Duggal, Ken Uchino, Sung-Min Cho, Andrew B. Buletko
Summary: This study retrospectively analyzed the structural brain injuries detected by brain MRI among patients with ARDS at a single tertiary center in the United States from January 2010 to October 2018 (pre-COVID era). The results showed that bilateral globus pallidus infarcts and diffuse rather than focal hemorrhage were more common in patients with ARDS. The study suggests that structural brain injuries exist in patients with ARDS.
NEUROCRITICAL CARE
(2023)
Article
Multidisciplinary Sciences
Erlina Burhan, Keibun Liu, Eva M. Marwali, Samuel Huth, Navy G. H. M. L. Wulung, Dafsah A. Juzar, Muhammad A. Taufik, Surya O. Wijaya, Dyah K. Wati, Neurinda P. Kusumastuti, Saptadi Yuliarto, Bhirowo Y. Pratomo, Erwin Pradian, Dadang H. Somasetia, Desy Rusmawatiningtyas, Arie Z. Fatoni, Jose M. Mandei, Eka Y. Lantang, Fajar Perdhana, Bambang P. Semedi, Muhammad Rayhan, Tiffany R. S. Tarigan, Nicole White, Gianluigi L. Bassi, Jacky Y. Suen, John F. Fraser
Summary: This study describes the characteristics and outcomes of patients admitted to ICU during the early stages of the COVID-19 pandemic in Indonesia.
Article
Critical Care Medicine
Enric Barbeta, Marta Arrieta, Ana Motos, Joaquim Bobi, Hua Yang, Minlan Yang, Giacomo Tanzella, Pierluigi Di Ginnatale, Stefano Nogas, Carmen Rosa Vargas, Roberto Cabrera, Denise Battaglini, Andrea Meli, Kasra Kiarostami, Nil Vazquez, Laia Fernandez-Barat, Montserrat Rigol, Ricard Mellado-Artigas, Gerard Frigola, Marta Camprubi-Rimblas, Pau Ferrer, Daniel Martinez, Antonio Artigas, Carlos Ferrando, Miquel Ferrer, Antoni Torres
Summary: This study successfully established an accurate animal model of ARDS induced by pulmonary sepsis. The model was created in pigs by inducing ARDS through pneumonia, the most common risk factor in humans, and analyzed the additional effect of ventilator-induced lung injury.
Correction
Critical Care Medicine
Bairbre A. McNicholas, Emanuele Rezoagli, Andrew J. Simpkin, Sankalp Khanna, Jacky Y. Suen, Pauline Yeung, Daniel Brodie, Gianluigi Li Bassi, Tai Pham, Giacomo Bellani, John F. Fraser, John Laffey, Cccc Consortium
Article
Critical Care Medicine
Bairbre A. A. McNicholas, Emanuele Rezoagli, Andrew J. J. Simpkin, Sankalp Khanna, Jacky Y. Y. Suen, Pauline Yeung, Daniel Brodie, Gianluigi Li Bassi, Tai Pham, Giacomo Bellani, John F. F. Fraser, John Laffey
Summary: AKI is a common and serious complication in COVID-19 patients, with different characteristics and outcomes compared to non-COVID-19 ARDS patients.