ApoE-mediated systemic nanodelivery of granzyme B and CpG for enhanced glioma immunotherapy

Brain-Targeted Codelivery of Bcl-2/Bcl-xl and Mcl-1 Inhibitors by Biomimetic Nanoparticles for Orthotopic Glioblastoma Therapy

(2022) Wenya He et al.   ACS Nano

Immunotherapy of Malignant Glioma by Noninvasive Administration of TLR9 Agonist CpG Nano‐Immunoadjuvant

(2022) Jingjing Wei et al.   Advanced Science

A Biomimetic Drug Delivery System by Integrating Grapefruit Extracellular Vesicles and Doxorubicin-Loaded Heparin-Based Nanoparticles for Glioma Therapy

(2021) Wenbo Niu et al.   NANO LETTERS

Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection

(2021) Jing Zhang et al.   Nature Nanotechnology

Rethinking CRITID Procedure of Brain Targeting Drug Delivery: Circulation, Blood Brain Barrier Recognition, Intracellular Transport, Diseased Cell Targeting, Internalization, and Drug Release

(2021) Shaobo Ruan et al.   Advanced Science

Systemic administration of polymersomal oncolytic peptide LTX-315 combining with CpG adjuvant and anti-PD-1 antibody boosts immunotherapy of melanoma

(2021) Yifeng Xia et al.   JOURNAL OF CONTROLLED RELEASE

Tumor‐Microenvironment‐Responsive Nanomedicine for Enhanced Cancer Immunotherapy

(2021) Shaojun Peng et al.   Advanced Science

Development and in vitro evaluation of a new adjuvant system containing Salmonella Typhi porins and chitosan

(2020) Selin Yüksel et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Transferrin-binding peptide functionalized polymersomes mediate targeted doxorubicin delivery to colorectal cancer in vivo

(2020) Yaohua Wei et al.   JOURNAL OF CONTROLLED RELEASE

Immunotherapy for Malignant Glioma: Current Status and Future Directions

(2020) Hongxiang Wang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses

(2020) Yu Chao et al.   Science Advances

CD44-targeted vesicles encapsulating granzyme B as artificial killer cells for potent inhibition of human multiple myeloma in mice

(2020) Yinan Zhong et al.   JOURNAL OF CONTROLLED RELEASE

Hypoxia-sensitive supramolecular nanogels for the cytosolic delivery of ribonuclease A as a breast cancer therapeutic

(2020) Xinghui Si et al.   JOURNAL OF CONTROLLED RELEASE

Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions

(2020) Patrick Y Wen et al.   NEURO-ONCOLOGY

Immunotherapy in Glioblastoma: Current Shortcomings and Future Perspectives

(2020) Bas Weenink et al.   Cancers

GE11 peptide-installed chimaeric polymersomes tailor-made for high-efficiency EGFR-targeted protein therapy of orthotopic hepatocellular carcinoma

(2020) Cheng Zhou et al.   Acta Biomaterialia

Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation

(2020) Wenxing Gu et al.   JOURNAL OF CONTROLLED RELEASE

Plant Virus-Like Particle In Situ Vaccine for Intracranial Glioma Immunotherapy

(2019) Kerstetter-Fogle et al.   Cancers

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

(2019) Cyril Neftel et al.   CELL

Mechanisms of immunotherapy resistance: lessons from glioblastoma

(2019) Christopher M. Jackson et al.   NATURE IMMUNOLOGY

Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes

(2019) Chunwan Lu et al.   Journal for ImmunoTherapy of Cancer

CD44‐Specific A6 Short Peptide Boosts Targetability and Anticancer Efficacy of Polymersomal Epirubicin to Orthotopic Human Multiple Myeloma

(2019) Wenxing Gu et al.   ADVANCED MATERIALS

Enhancing Triple Negative Breast Cancer Immunotherapy by ICG‐Templated Self‐Assembly of Paclitaxel Nanoparticles

(2019) Bing Feng et al.   ADVANCED FUNCTIONAL MATERIALS

TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma

(2019) Matthew J. Reilley et al.   Journal for ImmunoTherapy of Cancer

Mitochondria-Targeting Immunogenic Cell Death Inducer Improves the Adoptive T-Cell Therapy Against Solid Tumor

(2019) Qingzhi Jiang et al.   Frontiers in Oncology

Medium dose intermittent cyclophosphamide induces immunogenic cell death and cancer cell autonomous type I interferon production in glioma models

(2019) Bin Du et al.   CANCER LETTERS

iRGD Modified Chemo-immunotherapeutic Nanoparticles for Enhanced Immunotherapy against Glioblastoma

(2018) Jing Kuang et al.   ADVANCED FUNCTIONAL MATERIALS

Protein Toxin Chaperoned by LRP-1-Targeted Virus-Mimicking Vesicles Induces High-Efficiency Glioblastoma Therapy In Vivo

(2018) Yu Jiang et al.   ADVANCED MATERIALS

Current state of immunotherapy for glioblastoma

(2018) Michael Lim et al.   Nature Reviews Clinical Oncology

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

(2018) Yu Chao et al.   Nature Biomedical Engineering

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

(2018) Denzil Furtado et al.   ADVANCED MATERIALS

Oxaliplatin disrupts pathological features of glioma cells and associated macrophages independent of apoptosis induction

(2018) Nathan B. Roberts et al.   JOURNAL OF NEURO-ONCOLOGY

Apolipoprotein E Peptide-Directed Chimeric Polymersomes Mediate an Ultrahigh-Efficiency Targeted Protein Therapy for Glioblastoma

(2018) Yu Jiang et al.   ACS Nano

Granzyme B-loaded, cell-selective penetrating and reduction-responsive polymersomes effectively inhibit progression of orthotopic human lung tumor in vivo

(2018) Weijing Yang et al.   JOURNAL OF CONTROLLED RELEASE

Boosting RNAi therapy for orthotopic glioblastoma with nontoxic brain-targeting chimaeric polymersomes

(2018) Yanan Shi et al.   JOURNAL OF CONTROLLED RELEASE

Conventional Anti-glioblastoma Chemotherapy Affects Proteoglycan Composition of Brain Extracellular Matrix in Rat Experimental Model in vivo

(2018) Alexandra Y. Tsidulko et al.   Frontiers in Pharmacology

Maximizing Synergistic Activity When Combining RNAi and Platinum-Based Anticancer Agents

(2017) Haihua Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A bifunctional nanomodulator for boosting CpG-mediated cancer immunotherapy

(2017) Zhenzhen Wang et al.   Nanoscale

Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model

(2016) Mao Ouyang et al.   PLoS One

Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma.

(2015) Giovanna Lollo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comparison of Five Peptide Vectors for Improved Brain Delivery of the Lysosomal Enzyme Arylsulfatase A

(2014) A. Bockenhoff et al.   JOURNAL OF NEUROSCIENCE

Intracerebral administration of CpG oligonucleotide for patients with recurrent glioblastoma: a phase II study

(2011) A. Carpentier et al.   NEURO-ONCOLOGY

Induction of Anti-Glioma Natural Killer Cell Response following Multiple Low-Dose Intracerebral CpG Therapy

(2010) D. Alizadeh et al.   CLINICAL CANCER RESEARCH

Cytochrome c: functions beyond respiration

(2008) Yong-Ling P. Ow et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY