The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides

Effect of ion-pairing reagent hydrophobicity on liquid chromatography and mass spectrometry analysis of oligonucleotides

(2022) Michael Donegan et al.   JOURNAL OF CHROMATOGRAPHY A

Using Hybrid Organic–Inorganic Surface Technology to Mitigate Analyte Interactions with Metal Surfaces in UHPLC

(2021) Mathew DeLano et al.   ANALYTICAL CHEMISTRY

Mitigation of analyte loss on metal surfaces in liquid chromatography

(2021) Martin Gilar et al.   JOURNAL OF CHROMATOGRAPHY A

Reducing Metal-ion Mediated Adsorption of Acidic Peptides in RPLC-Based Assays Using Hybrid Silica Chromatographic Surfaces

(2021) Robert E. Birdsall et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Analytical characterization of DNA and RNA oligonucleotides by hydrophilic interaction liquid chromatography-tandem mass spectrometry

(2021) Ming Huang et al.   JOURNAL OF CHROMATOGRAPHY A

Recent advances in therapeutic nucleic acids and their analytical methods

(2021) Jadera Talap et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Assessing the impact of nonspecific binding on oligonucleotide bioanalysis

(2021) Jennifer M Nguyen et al.   Bioanalysis

Impact of Nonspecific Adsorption to Metal Surfaces in Ion Pair-RP LC-MS Impurity Analysis of Oligonucleotides

(2021) Guilherme J. Guimaraes et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Characterization of Antisense Oligonucleotide Impurities by Ion-Pairing Reversed-Phase and Anion Exchange Chromatography Coupled to Hydrophilic Interaction Liquid Chromatography/Mass Spectrometry Using a Versatile Two-Dimensional Liquid Chromatography Setup

(2020) Alexandre Goyon et al.   ANALYTICAL CHEMISTRY

Characterization of therapeutic oligonucleotides by liquid chromatography

(2020) Alexandre Goyon et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The powerful world of antisense oligonucleotides: From bench to bedside

(2020) Anaïs M. Quemener et al.   Wiley Interdisciplinary Reviews-RNA

Application of hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry for the retention and sensitivity studies of antisense oligonucleotides

(2020) Anna Kilanowska et al.   JOURNAL OF CHROMATOGRAPHY A

Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development

(2020) Karishma Dhuri et al.   Journal of Clinical Medicine

Recent developments in the characterization of nucleic acids by liquid chromatography, capillary electrophoresis, ion mobility, and mass spectrometry (2010–2020)

(2020) Inês C. Santos et al.   JOURNAL OF SEPARATION SCIENCE

Evaluation of alkylamines and stationary phases to improve LC–MS of oligonucleotides

(2020) Michael G. Bartlett et al.   BIOMEDICAL CHROMATOGRAPHY

The role of fluoroalcohols as counter anions for ion-pairing reversed-phase liquid chromatography/high-resolution electrospray ionization mass spectrometry analysis of oligonucleotides

(2019) Rong Liu et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Small alkyl amines as ion-pair reagents for the separation of positional isomers of impurities in phosphate diester oligonucleotides

(2019) Stilianos G. Roussis et al.   JOURNAL OF CHROMATOGRAPHY A

Oligonucleotide analysis by hydrophilic interaction liquid chromatography-mass spectrometry in the absence of ion-pair reagents

(2019) Peter A. Lobue et al.   JOURNAL OF CHROMATOGRAPHY A

Evaluation of hydrophilic interaction liquid chromatography, capillary zone electrophoresis and drift tube ion-mobility quadrupole time of flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides

(2019) Alice Demelenne et al.   JOURNAL OF CHROMATOGRAPHY A

Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease

(2019) Jinkuk Kim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Therapeutic Oligonucleotides: State of the Art

(2018) C.I. Edvard Smith et al.   Annual Review of Pharmacology and Toxicology

Understanding and manipulating the separation in hydrophilic interaction liquid chromatography

(2017) David V. McCalley   JOURNAL OF CHROMATOGRAPHY A

Application of hydrophilic interaction liquid chromatography coupled with mass spectrometry in the analysis of phosphorothioate oligonucleotides in serum

(2017) Sylwia Studzińska et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Assessing the Interplay between the Physicochemical Parameters of Ion-Pairing Reagents and the Analyte Sequence on the Electrospray Desorption Process for Oligonucleotides

(2017) Babak Basiri et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The chemical evolution of oligonucleotide therapies of clinical utility

(2017) Anastasia Khvorova et al.   NATURE BIOTECHNOLOGY

Analysis of oligonucleotides by ion-pairing hydrophilic interaction liquid chromatography/electrospray ionization mass spectrometry

(2017) Lingzhi Gong   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Some factors that can lead to poor peak shape in hydrophilic interaction chromatography, and possibilities for their remediation

(2016) James C. Heaton et al.   JOURNAL OF CHROMATOGRAPHY A

The Role of Fluorinated Alcohols as Mobile Phase Modifiers for LC-MS Analysis of Oligonucleotides

(2016) Babak Basiri et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Comparing ion-pairing reagents and counter anions for ion-pair reversed-phase liquid chromatography/electrospray ionization mass spectrometry analysis of synthetic oligonucleotides

(2015) Lingzhi Gong   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Theoretical Models of Ion Pair Chromatography: A Close Up of Recent Literature Production

(2014) Teresa Cecchi   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES

Separation and identification of phosphorothioate oligonucleotides by HILIC-ESIMS

(2013) Renee Easter et al.   Analytical Methods

Comparison of mobile-phase systems commonly applied in liquid chromatography-mass spectrometry of nucleic acids

(2013) Robert Erb et al.   ELECTROPHORESIS

Evaluation of mobile phase composition for enhancing sensitivity of targeted quantification of oligonucleotides using ultra-high performance liquid chromatography and mass spectrometry: Application to phosphorothioate deoxyribonucleic acid

(2013) Buyun Chen et al.   JOURNAL OF CHROMATOGRAPHY A

Systematic optimization of ion-pairing agents and hexafluoroisopropanol for enhanced electrospray ionization mass spectrometry of oligonucleotides

(2013) A. Cary McGinnis et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Comparing ion-pairing reagents and sample dissolution solvents for ion-pairing reversed-phase liquid chromatography/electrospray ionization mass spectrometry analysis of oligonucleotides

(2013) Lingzhi Gong et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Comprehensive hydrophilic interaction and ion-pair reversed-phase liquid chromatography for analysis of di- to deca-oligonucleotides

(2011) Qin Li et al.   JOURNAL OF CHROMATOGRAPHY A

Separation and identification of oligonucleotides by hydrophilic interaction liquid chromatography (HILIC)—inductively coupled plasma mass spectrometry (ICPMS)

(2010) Renee N. Easter et al.   ANALYST

Adsorption of Nucleic Acid Components on Rutile (TiO2) Surfaces

(2010) H. James Cleaves et al.   ASTROBIOLOGY

Polar Anionic Metabolome Analysis by Nano-LC/MS with a Metal Chelating Agent

(2009) Khin Than Myint et al.   ANALYTICAL CHEMISTRY

Ion Pairing Chromatography

(2008) Teresa Cecchi   CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY