Antimicrobial activity of cefepime/zidebactam (WCK 5222), a β-lactam/β-lactam enhancer combination, against clinical isolates of Gram-negative bacteria collected worldwide (2018–19)

In vitro evolution of cefepime/zidebactam (WCK 5222) resistance in Pseudomonas aeruginosa: dynamics, mechanisms, fitness trade-off and impact on in vivo efficacy

(2021) Isabel Barceló et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Application of Next-Generation Sequencing for Characterization of Surveillance and Clinical Trial Isolates: Analysis of the Distribution of β-lactamase Resistance Genes and Lineage Background in the United States

(2019) Rodrigo E Mendes et al.   Open Forum Infectious Diseases

The Importance of Antimicrobial Resistance Monitoring Worldwide and the Origins of SENTRY Antimicrobial Surveillance Program

(2019) Andrew S Fuhrmeister et al.   Open Forum Infectious Diseases

The Novel β-Lactam Enhancer Zidebactam Augments the In Vivo Pharmacodynamic Activity of Cefepime in a Neutropenic Mouse Lung Acinetobacter baumannii Infection Model

(2019) S. S. Bhagwat et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro and in vivo activity of β-lactams in combination with novel β-lactam enhancers, zidebactam and WCK 5153, against multidrug-resistant metallo-β-lactamase producing Klebsiella pneumoniae

(2019) Bartolome Moya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An update on β-lactamase inhibitor discovery and development

(2018) Jean-Denis Docquier et al.   DRUG RESISTANCE UPDATES

Ceftazidime-Avibactam: A Review in the Treatment of Serious Gram-Negative Bacterial Infections

(2018) Matt Shirley   DRUGS

Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234

(2018) Krisztina M. Papp-Wallace et al.   JOURNAL OF MEDICINAL CHEMISTRY

Assessment of the In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) Against Carbapenem-Resistant Acinetobacter baumannii in the Neutropenic Murine Lung Infection Model

(2018) Lindsay M. Avery et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vivo Efficacy of Humanized WCK 5222 (Cefepime-Zidebactam) Exposures against Carbapenem-Resistant Acinetobacter baumannii in the Neutropenic Thigh Model

(2018) Safa S. Almarzoky Abuhussain et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro activity of cefepime/zidebactam (WCK 5222) against Gram-negative bacteria

(2017) David M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY