Patient-reported health-related quality of life from a randomized, placebo-controlled phase 2 trial of zuranolone in adults with major depressive disorder

The Economic Burden of Adults with Major Depressive Disorder in the United States (2010 and 2018)

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Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABAA receptor positive allosteric modulator

(2020) Alison L. Althaus et al.   NEUROPHARMACOLOGY

Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions

(2019) Manoela V. Fogaça et al.   Frontiers in Cellular Neuroscience

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

(2019) Ronald S. Duman et al.   NEURON

SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies

(2019) Ethan Hoffmann et al.   CLINICAL PHARMACOKINETICS

Trial of SAGE-217 in Patients with Major Depressive Disorder

(2019) Handan Gunduz-Bruce et al.   NEW ENGLAND JOURNAL OF MEDICINE

The State of US Health, 1990-2016

(2018) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)A Receptor

(2017) Gabriel Martinez Botella et al.   JOURNAL OF MEDICINAL CHEMISTRY

Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism

(2017) Amit Modgil et al.   NEUROPHARMACOLOGY

The Role of Patient-Reported Outcome Measures in Value-Based Payment Reform

(2017) Lee Squitieri et al.   VALUE IN HEALTH

Insomnia in Patients With Depression: A STAR*D Report

(2017) Prabha Sunderajan et al.   CNS SPECTRUMS

Value-based Healthcare: Patient-reported Outcomes in Clinical Decision Making

(2016) Judith F. Baumhauer et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Assessment of health-related quality of life, mental health status and psychological distress based on the type of pharmacotherapy used among patients with depression

(2016) Drishti Shah et al.   QUALITY OF LIFE RESEARCH

Long-term antidepressant use: patient perspectives of benefits and adverse effects

(2016) Claire Cartwright et al.   Patient Preference and Adherence

Evaluation of functional health and well-being in patients receiving levomilnacipran ER for the treatment of major depressive disorder

(2015) Steven I. Blum et al.   JOURNAL OF AFFECTIVE DISORDERS

What is important in being cured from depression? Discordance between physicians and patients (1)

(2015) Koen Demyttenaere et al.   JOURNAL OF AFFECTIVE DISORDERS

Why are cortical GABA neurons relevant to internal focus in depression? A cross-level model linking cellular, biochemical and neural network findings

(2014) G Northoff et al.   MOLECULAR PSYCHIATRY

Risks of all-cause and suicide mortality in mental disorders: a meta-review

(2014) Edward Chesney et al.   World Psychiatry

Differential mortality rates in major and subthreshold depression: meta-analysis of studies that measured both

(2013) Pirn Cuijpers et al.   BRITISH JOURNAL OF PSYCHIATRY

Treatment of depression in type 2 diabetic patients: Effects on depressive symptoms, quality of life and metabolic control

(2013) Joana Nicolau et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Assessing health-related quality of life (HRQOL) in major depressive disorder (MDD): Do commonly used instruments meet EMA requirements for psychometric properties and content relevance

(2013) N. Danchenko et al.   VALUE IN HEALTH

Development and validation of a patient-report measure of fatigue associated with depression

(2011) Louis S. Matza et al.   JOURNAL OF AFFECTIVE DISORDERS

Quality of Life: The Ultimate Outcome Measure of Interventions in Major Depressive Disorder

(2011) Waguih William IsHak et al.   HARVARD REVIEW OF PSYCHIATRY

Health related quality of life in recurrent depression: A comparison with a general population sample

(2009) Mascha C. ten Doesschate et al.   JOURNAL OF AFFECTIVE DISORDERS

The Descriptive Epidemiology of Commonly Occurring Mental Disorders in the United States

(2008) Ronald C. Kessler et al.   Annual Review of Public Health

Quality of life outcomes among patients with depression after 6 months of starting treatment: Results from FINDER

(2008) Catherine Reed et al.   JOURNAL OF AFFECTIVE DISORDERS