New 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-N-(imidazolidin-2-ylidene)-4-chloro-5-methylbenzenesulfonamide Derivatives, Design, Synthesis and Anticancer Evaluation

Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells

(2021) Xian Hong et al.   BMC CANCER

Targeting mutant p53 for cancer therapy: direct and indirect strategies

(2021) Jiahao Hu et al.   Journal of Hematology & Oncology

Synthesis, Antitumor Evaluation, Molecular Modeling and Quantitative Structure–Activity Relationship (QSAR) of Novel 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-4-chloro-5-methyl-N-(1H-benzo[d]imidazol-2(3H)-ylidene)Benzenesulfonamides

(2020) Łukasz Tomorowicz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immune Checkpoint Inhibitors in Hepatocellular Cancer: Current Understanding on Mechanisms of Resistance and Biomarkers of Response to Treatment

(2020) Amblessed E. Onuma et al.   GENE EXPRESSION

Gaseous signaling molecules and their application in resistant cancer treatment: from invisible to visible

(2019) Qingbin Cui et al.   Future Medicinal Chemistry

Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists

(2018) Sara Guariento et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, molecular structure, and metabolic stability of new series of N' -(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)-1-(5-phenyl-1 H -pyrazol-1-yl)amidine as potential anti-cancer agents

(2018) Aneta Pogorzelska et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600–Mutant Anaplastic Thyroid Cancer

(2018) Vivek Subbiah et al.   JOURNAL OF CLINICAL ONCOLOGY

Modulating ROS to overcome multidrug resistance in cancer

(2018) Qingbin Cui et al.   DRUG RESISTANCE UPDATES

Targeting the MDM2–p53 Protein–Protein Interaction for New Cancer Therapy: Progress and Challenges

(2017) Shaomeng Wang et al.   Cold Spring Harbor Perspectives in Medicine

Chrysin-piperazine conjugates as antioxidant and anticancer agents

(2016) Rahul V. Patel et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Clinical Overview of MDM2/X-Targeted Therapies

(2016) Andrew Burgess et al.   Frontiers in Oncology

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

FDA Approval Summary: Vemurafenib for Treatment of Unresectable or Metastatic Melanoma with the BRAFV600E Mutation

(2014) G. Kim et al.   CLINICAL CANCER RESEARCH

Best management of locally advanced inoperable breast cancer

(2013) Giuseppe Curigliano et al.   EJC SUPPLEMENTS

Practical Method for Parallel Synthesis of Diversely Substituted 1- henylpiperazines

(2012) Igor Konstantinov et al.   LETTERS IN ORGANIC CHEMISTRY

Synthesis and molecular structure of novel 2-(alkylthio)-4-chloro-N-(4,5-dihydro-5-oxo-1H-1,2,4-triazol-3-yl)-5-methylbenzenesulfonamides with potential anticancer activity

(2012) Jarosław Sławiński et al.   MONATSHEFTE FUR CHEMIE

Antioxidant, cytotoxicity, and QSAR study of 1-adamantylthio derivatives of 3-picoline and phenylpyridines

(2011) Apilak Worachartcheewan et al.   MEDICINAL CHEMISTRY RESEARCH

Assessment of the Evolution of Cancer Treatment Therapies

(2011) Manuel Arruebo et al.   Cancers

The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death

(2009) Nikhil S. Chari et al.   APOPTOSIS

Synthesis and in vitro evaluation of 2,4-diamino-1,3,5-triazine derivatives as neuronal voltage-gated sodium channel blockers

(2009) Xiang Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mutant p53 mediates survival of breast cancer cells

(2009) L Y Lim et al.   BRITISH JOURNAL OF CANCER

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY