LRF Promotes Indirectly Advantageous Chromatin Conformation via BGLT3-lncRNA Expression and Switch from Fetal to Adult Hemoglobin

ETV6 Regulates Hemin-Induced Erythroid Differentiation of K562 Cells through Mediating the Raf/MEK/ERK Pathway

(2022) Zhaopeng Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Transcription factor competition at the γ-globin promoters controls hemoglobin switching

(2021) Nan Liu et al.   NATURE GENETICS

A unified model of human hemoglobin switching through single-cell genome editing

(2021) Yong Shen et al.   Nature Communications

Hemin accumulation and identification of a heme‐binding protein clan in K562 cells by proteomic and computational analysis

(2021) Vasiliki‐Dimitra C. Tsolaki et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulatory association of long noncoding RNAs and chromatin accessibility facilitates erythroid differentiation

(2021) Yunxiao Ren et al.   Blood Advances

Mapping of scaffold/matrix attachment regions in human genome: a data mining exercise

(2019) Nitin Narwade et al.   NUCLEIC ACIDS RESEARCH

Downregulation of Transcription Factor LRF/ZBTB7A Increases Fetal Hemoglobin Expression in β-Thalassemia/Hemoglobin E Erythroid Cells

(2019) Sukanya Chumchuen et al.   BLOOD

Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus

(2018) Chiara Antoniani et al.   BLOOD

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

MiR-27a Promotes Hemin-Induced Erythroid Differentiation of K562 Cells by Targeting CDC25B

(2018) Dongsheng Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

(2018) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

Fetal γ-globin genes are regulated by the BGLT3 long non-coding RNA locus

(2018) Maria Soledad Ivaldi et al.   BLOOD

Structural Basis of DNMT1 and DNMT3A-Mediated DNA Methylation

(2018) Wendan Ren et al.   Genes

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element

(2017) Peng Huang et al.   GENES & DEVELOPMENT

CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation

(2016) Matthias Merkenschlager et al.   Annual Review of Genomics and Human Genetics

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

(2016) T. Masuda et al.   SCIENCE

SMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster

(2016) Jinumary Mathai et al.   Scientific Reports

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin

(2015) Alessia Finotti et al.   EXPERIMENTAL HEMATOLOGY

An Overview of Genome Organization and How We Got There: from FISH to Hi-C

(2015) James Fraser et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors

(2015) Samuel Lessard et al.   Genome Medicine

Reactivation of Developmentally Silenced Globin Genes by Forced Chromatin Looping

(2014) Wulan Deng et al.   CELL

A long noncoding RNA critically regulates Bcr-Abl-mediated cellular transformation by acting as a competitive endogenous RNA

(2014) G Guo et al.   ONCOGENE

Clinical experience with fetal hemoglobin induction therapy in patients with  -thalassemia

(2013) K. M. Musallam et al.   BLOOD

Updates of the HbVar database of human hemoglobin variants and thalassemia mutations

(2013) Belinda Giardine et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-486-3p Regulates γ-Globin Expression in Human Erythroid Cells by Directly Modulating BCL11A

(2013) Valentina Lulli et al.   PLoS One

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Global DNA Hypomethylation in Peripheral Blood Leukocytes as a Biomarker for Cancer Risk: A Meta-Analysis

(2012) Hae Dong Woo et al.   PLoS One

Involvement of miRNA in erythroid differentiation

(2012) Nicoletta Bianchi et al.   Epigenomics

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

(2012) Zari Dastani et al.   PLoS Genetics

A Functional Element Necessary for Fetal Hemoglobin Silencing

(2011) Vijay G. Sankaran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

(2010) Joseph Borg et al.   NATURE GENETICS

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

(2010) Dewang Zhou et al.   NATURE GENETICS

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

(2008) S. Cuddapah et al.   GENOME RESEARCH

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY

Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of β-Thalassemia and Sickle-Cell Anemia

(2007) Nicoletta Bianchi et al.   Evidence-based Complementary and Alternative Medicine