Bio-magnetic pulsatile CuO- Fe3O4 hybrid nanofluid flow in a vertical irregular channel in a suspension of body acceleration

Mathematical modelling of biological fluids is essential in various medical disciplines. The current work has many biomechanical applications, including radiation therapy for lung cancer treatment and magnetic field strength to regulate blood flow during surgery. The current model deals with the pulsatile hybrid nanofluid flow in a vertically permeable irregular channel under the influence of externally applied body acceleration. Thermal radiation and heat source have been included in the heat transfer analysis. The velocity, temperature, heat transfer rate, and isothermal lines are produced using the perturbation approach to evaluate coupled equations with the nonlinear problem. In addition, response surface method is executed to probe the sensitivity of effective flow field parameters on the heat transfer rate. It is found that the hybrid nanoparticles expose a lower blood temperature than the mono nanoparticles; as a result, the hybrid nanoparticles have better drug delivery performance. The blood velocity decreases with increasing the values of the body force parameter. In addition, the blood flow is higher for CuO nanofluid than the CuO-Fe3O4 hybrid nanofluid, but this case is quite the opposite for lower values of frequency parameter.

Automated summary

Mathematical modelling of biological fluids is crucial in various medical fields. This study focuses on the pulsatile flow of hybrid nanofluids in vertically permeable irregular channels, considering thermal radiation and heat source effects. The results demonstrate that hybrid nanoparticles can lower blood temperature and enhance drug delivery performance.