Bortezomib potentiates the antitumor effect of tributyltin(IV) ferulate in colon cancer cells exacerbating ER stress and promoting apoptosis

The Good and Bad of Nrf2: An Update in Cancer and New Perspectives in COVID-19

(2021) Sonia Emanuele et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tributyltin(IV) Butyrate: A Novel Epigenetic Modifier with ER Stress- and Apoptosis-Inducing Properties in Colon Cancer Cells

(2021) Michela Giuliano et al.   MOLECULES

The efficacy and mechanism of proteasome inhibitors in solid tumor treatment

(2021) Lei Zhang et al.   Recent Patents on Anti-Cancer Drug Discovery

New Insights into Curcumin- and Resveratrol-Mediated Anti-Cancer Effects

(2021) Andrea Arena et al.   Pharmaceuticals

Tributyltin(IV) ferulate, a novel synthetic ferulic acid derivative, induces autophagic cell death in colon cancer cells: From chemical synthesis to biochemical effects

(2020) Claudia Pellerito et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

p62: Friend or Foe? Evidences for OncoJanus and NeuroJanus Roles

(2020) Sonia Emanuele et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Activating KRAS, NRAS, and BRAF mutants enhance proteasome capacity and reduce endoplasmic reticulum stress in multiple myeloma

(2020) Fazal Shirazi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting poor proteasomal function with radioiodine eliminates CT26 colon cancer stem cells resistant to bortezomib therapy

(2020) Jin Hee Lee et al.   Scientific Reports

Bortezomib for the Treatment of Hematologic Malignancies: 15 Years Later

(2019) Pawel Robak et al.   Drugs in research & development

Proteasome Inhibitor Drugs

(2019) Lloyd D. Fricker   Annual Review of Pharmacology and Toxicology

FOXD3, frequently methylated in colorectal cancer, acts as a tumor suppressor and induces tumor cell apoptosis under ER stress via p53

(2019) Ming Xu et al.   CARCINOGENESIS

The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells

(2019) Marianna Lauricella et al.   Antioxidants

p53-Mediated Oxidative Stress Enhances Indirubin-3′-Monoxime-Induced Apoptosis in HCT116 Colon Cancer Cells by Upregulating Death Receptor 5 and TNF-Related Apoptosis-Inducing Ligand Expression

(2019) Matharage Gayani Dilshara et al.   Antioxidants

Recent Advancements in Organotin(IV) Complexes as Potential Anticancer Agents

(2018) Jai Devi et al.   Anti-Cancer Agents in Medicinal Chemistry

The Double-Edged Sword Profile of Redox Signaling: Oxidative Events As Molecular Switches in the Balance between Cell Physiology and Cancer

(2018) Sonia Emanuele et al.   CHEMICAL RESEARCH IN TOXICOLOGY

2-Aminoethoxydiphenylborane sensitizes anti-tumor effect of bortezomib via suppression of calcium-mediated autophagy

(2018) Yuan Qing Qu et al.   Cell Death & Disease

Antioxidant Properties of Ferulic Acid and Its Possible Application

(2018) Kamila Zduńska et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Sequential treatment with celecoxib and bortezomib enhances the ER stress‑mediated autophagy‑associated cell death of colon cancer cells

(2018) Ga‑Bin Park et al.   Oncology Letters

Loperamide overcomes the resistance of colon cancer cells to bortezomib by inducing CHOP-mediated paraptosis-like cell death

(2018) In Young Kim et al.   BIOCHEMICAL PHARMACOLOGY

Endoplasmic-reticulum stress pathway-associated mechanisms of action of proteasome inhibitors in multiple myeloma

(2016) Masaki Ri   INTERNATIONAL JOURNAL OF HEMATOLOGY

Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor

(2016) Tingyu Wu et al.   MOLECULAR CANCER THERAPEUTICS

The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells

(2015) ANTONIETTA NOTARO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Synthesis, chemical characterization, computational studies and biological activity of new DNA methyltransferases (DNMTs) specific inhibitor. Epigenetic regulation as a new and potential approach to cancer therapy

(2015) C. Pellerito et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthesis, chemical characterization and biological activity of new histone acetylation/deacetylation specific inhibitors: A novel and potential approach to cancer therapy

(2013) Ornella Pellerito et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Tri- and diorganotin(IV) complexes of biologically important orotic acid: Synthesis, spectroscopic studies, in vitro anti-cancer, DNA fragmentation, enzyme assays and in vivo anti-inflammatory activities

(2012) Mala Nath et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Good Caco-2 cell culture practices

(2012) Manuela Natoli et al.   TOXICOLOGY IN VITRO

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

(2011) Min Ni et al.   BIOCHEMICAL JOURNAL