Article
Chemistry, Analytical
Datong Wu, Cong Ma, Fei Pan, Yongxin Tao, Yong Kong
Summary: An electroactive chiral polymer (S,S)-p-CVB-Fc was designed and synthesized to detect nonelectroactive samples using electrochemical techniques. It can be fixed on the surface of a glassy carbon electrode as an electrochemical chiral sensor, showing clear discrimination in the response of peak current towards non-electroactive amino acids such as proline, threonine, and alanine. The current work enlarges the testing scope of chiral samples in the field of chiral electroanalysis using an electroactive sensor.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Nijuan Liu, Jingjing Liu, Xiaohui Niu, Jia Wang, Ruibin Guo, Zunli Mo
Summary: A facile chiral composite (3D-NGMWCNT@(S,S)-CIL) with excellent electrochemical performance was prepared by integrating 3D-NGMWCNT and (S,S)-CIL. The constructed sensor showed high sensitivity and stability for enantioselective recognition of Trp enantiomers. This novel sensor provides an efficient and convenient strategy for chiral enantioselective recognition.
Article
Chemistry, Analytical
Qian-xiu Pan, Yun-cong Yang, Ning-ning Zhao, Baogang Zhang, Lin Cui, Chun-yang Zhang
Summary: A chiral electrochemical sensor based on copper-amino acid mercaptide nanorods (L-CuCys NRs) has been developed for discriminating tryptophan isomers. This sensor demonstrates high stability, good repeatability, easy fabrication, low cost, and efficient discrimination of tryptophan isomers.
ANALYTICA CHIMICA ACTA
(2023)
Article
Nanoscience & Nanotechnology
Nafiseh Fahimi-Kashani, Zahra Jafar-Nezhad Ivrigh, Arafeh Bigdeli, Mohammad Reza Hormozi-Nezhad
Summary: Chirality-induced nanomaterials are used for discrimination of chiral targets, with chiroptical activities observed in CdTe quantum dots supramolecular assemblies. The distinct fluorescence response patterns of L- and D-Trp enable construction of a logic gate system. The wide range color tonalities facilitate simple visual tracking of enantiomeric excess determination of L-Trp.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Analytical
Sha Han, Luhua Wang, Hongxia Li, Xiaohui Niu, Yanni Li, Xiaoyu Liu, Kunjie Wang
Summary: In this study, CMC-MIL-88(Fe) chiral material was synthesized and characterized using various techniques. It was then modified on a GCE to form an electrochemical chiral platform for the detection of tryptophan. The enantioselectivity of the platform was evaluated using cyclic voltammetry and differential pulse voltammetry, and it showed good selectivity towards L-Trp.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Hebing Pei, Jia Wang, Xuening Jin, Xuejiao Zhang, Wanjing Liu, Ruibin Guo, Nijuan Liu, Zunli Mo
Summary: A novel chiral sensing platform utilizing glutamic acid-functionalized graphene-gold nanoparticles was developed for enantioselective recognition of tryptophan. The synthesized chiral composites demonstrated successful recognition of enantiomers, with RGO-Au/L-Glu/GCE showing the highest recognition efficiency. The interface exhibited good stability and reproducibility, making it a promising tool for chiral sensing.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Jia Wang, Zunli Mo, Nijuan Liu, Ruibin Guo, Chao Shuai, Fang Chen, Yongxin Du, Jingjing Liu, Guigui Liu, Qibing Dong, Qinqin Gao, Ying Chen, Wentong Liu
Summary: A simple and effective chiral selector based on Cu2+ and ?-cyclodextrin was reported, which self-assembled with sodium alginate as a chiral sensor. The composite of C3N4 and Ppy was utilized as an electroactive material for enantiomeric selection of tryptophan. The sensor showed good selectivity, low affinity to L-Trp, higher peak current, and stronger binding ability to D-Trp.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Tong Li, Yuanyuan Wang, Xianwen Kan
Summary: A novel electrochemical chiral sensor was developed for discriminating tryptophan using Au@Pt bimetallic nanoparticles, poly(cysteine), and Cu2+-modified beta-cyclodextrin. The sensor showed good selectivity, stability, and reproducibility in detecting tryptophan in serum samples.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Hongxia Li, Sha Han, Xiaohui Niu, Kunjie Wang
Summary: Chirality plays a crucial role in nature. In this study, a highly ordered and non-clustered crystalline material UiO-88-LP was synthesized and applied in electrochemical chiral interface, successfully recognizing the configuration of tryptophan. The experiment demonstrated that UiO-88-LP/GCE possessed an enantiomeric resolution of amino acids.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biophysics
Brij Mohan, Sandeep Kumar, Hui Xi, Shixuan Ma, Zhiyu Tao, Tiantian Xing, Hengzhi You, Yang Zhang, Peng Ren
Summary: The study focuses on the application of sensors made of porous metal-organic frameworks (MOFs) in cancer biomarker detection, analyzing factors such as fabrication strategies and structural properties that influence sensing performance, and proposes an innovative technique for detecting cancer biomarkers using luminescence and electrochemical sensors.
BIOSENSORS & BIOELECTRONICS
(2022)
Review
Chemistry, Multidisciplinary
Mingxuan Ma, Jiahuan Chen, Hongyu Liu, Zhonghua Huang, Fuhong Huang, Quanliang Li, Yuan Xu
Summary: This review discusses the characteristics, construction strategies, and recent advances in applications of chiral metal-organic frameworks (CMOFs). CMOFs have the characteristics of structural diversity and functional tunability, and find important applications in fields such as chiral identification and enantiomer separation. The review focuses on three effective strategies for constructing CMOFs and summarizes the recent progress in various applications of CMOFs.
Article
Chemistry, Analytical
L. R. Zagitova, V. N. Maistrenko, Yu A. Yarkaeva, V. V. Zagitov, R. A. Zilberg, P. Kovyazin, L. Parfenova
Summary: A chiral voltammetric sensor based on carbon black paste electrode was developed for the recognition and determination of tryptophan enantiomers. The sensor showed better recognition towards L-TRP compared to D-TRP, with a linear correlation between peak currents of TRP enantiomers and their concentration. Experimental results demonstrated satisfactory recoveries in human urine and blood plasma, with a detection limit of 1.71 pM for L-TRP and 2.23 pM for D-TRP.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Inorganic & Nuclear
Jiao Zou, Guo-Qing Zhao, Guo-Ling Zhao, Jin-Gang Yu
Summary: Chiral recognition is an important property of biomolecules, especially in biomolecular recognition, and it plays a specific role. Various methods, such as gas or liquid chromatography, capillary electrophoresis, etc., can be used for the separation and recognition of chiral isomers. Recently, chemical sensors and biosensors have been developed for the analysis of chiral compounds. Electrochemical analysis has achieved significant success in enantiomer recognition.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Analytical
Ya Liu, Li Jia
Summary: The study successfully fabricated L-tryptophan imprinted chitosan modified magnetic particles in a three-step process, achieving complete enantioseparation of chiral mixtures with high enantiomeric excess. The results highlight the great potential of the strategy for preparing chiral adsorbents in enantioseparation.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Weijia Jiang, Ran He, Han Lv, Xinheng He, Li Wang, Yanli Wei
Summary: Chiral recognition of amino acids is crucial in the fields of pharmaceuticals, medicine, and food science. In this study, a chiral sensing system using beta-cyclodextrin-coated sulfur quantum dots was developed for the selective fluorescence recognition of tryptophan enantiomers. The system exhibited high sensitivity and selectivity towards L-Trp and could potentially be used for chiral recognition of amino acid enantiomers.
