Novel insights on [1,2]oxazolo[5,4‐ e ]isoindoles on multidrug resistant acute myeloid leukemia cell line

GPCR Inhibition in Treating Lymphoma

(2022) Marilia Barreca et al.   ACS Medicinal Chemistry Letters

Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations

(2022) Vincenzo Cilibrasi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia

(2022) Manuela Labbozzetta et al.   Pharmaceuticals

Insight on pyrimido[5,4-g]indolizine and pyrimido[4,5-c]pyrrolo[1,2-a]azepine systems as promising photosensitizers on malignant cells

(2022) Marilia Barreca et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update

(2020) Jinyun Dong et al.   DRUG RESISTANCE UPDATES

Multidrug-related protein 1 (MRP1) polymorphisms rs129081, rs212090, and rs212091 predict survival in normal karyotype acute myeloid leukemia

(2020) Desiree Kunadt et al.   ANNALS OF HEMATOLOGY

An overview on anti-tubulin agents for the treatment of lymphoma patients

(2020) Marilia Barreca et al.   PHARMACOLOGY & THERAPEUTICS

Evaluation of [1,2]oxazolo[5,4-e]isoindoles in lymphoma cells

(2020) M. Barreca et al.   EUROPEAN JOURNAL OF CANCER

Secondary resistance to the PI3K inhibitor copanlisib in marginal zone lymphoma

(2020) A. Arribas et al.   EUROPEAN JOURNAL OF CANCER

Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types

(2020) Virginia Spanò et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemical molecular‐based approach to overcome multidrug resistance in cancer by targeting P‐glycoprotein (P‐gp)

(2020) Hang Zhang et al.   MEDICINAL RESEARCH REVIEWS

Mechanisms of drug resistance in acute myeloid leukemia

(2019) Jing Zhang et al.   OncoTargets and Therapy

The multi-factorial nature of clinical multidrug resistance in cancer

(2019) Yehuda G. Assaraf et al.   DRUG RESISTANCE UPDATES

How to address second and therapy‐related acute myelogenous leukaemia

(2019) Caspian Oliai et al.   BRITISH JOURNAL OF HAEMATOLOGY

Inhibit or Evade Multidrug Resistance P-Glycoprotein in Cancer Treatment

(2017) Deepali Waghray et al.   JOURNAL OF MEDICINAL CHEMISTRY

Detection approaches for multidrug resistance genes of leukemia

(2017) Ying Du et al.   Drug Design Development and Therapy

An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells

(2017) Min-Wu Chao et al.   Oncotarget

[1,2]Oxazolo[5,4- e ]isoindoles as promising tubulin polymerization inhibitors

(2016) Virginia Spanò et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma

(2016) Virginia Spanò et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-resistant Jurkat/A4 cells

(2015) Alex A Philchenkov et al.   CANCER BIOLOGY & THERAPY

Antimitotic drugs in the treatment of cancer

(2015) Rustelle Janse van Vuuren et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Preferential enlargement of leukemia cells using cytoskeletal-directed agents and cell cycle growth control parameters to induce sensitivity to low frequency ultrasound

(2015) Matthew Trendowski et al.   CANCER LETTERS

MPT0B169, a novel tubulin inhibitor, induces apoptosis in taxol-resistant acute myeloid leukemia cells through mitochondrial dysfunction and Mcl-1 downregulation

(2015) Che-Chuan Wang et al.   TUMOR BIOLOGY

BubR1 is frequently repressed in acute myeloid leukemia and its re-expression sensitizes cells to antimitotic therapy

(2013) D. Schnerch et al.   HAEMATOLOGICA

Pyrano[2,3-e]isoindol-2-ones, new angelicin heteroanalogues

(2009) Paola Barraja et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities

(2009) Manuela Labbozzetta et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Acute leukemia as a secondary malignancy in children and adolescents: Current findings and issues

(2008) Nobuko Hijiya et al.   CANCER