Progress in DNA Aptamers as Recognition Components for Protein Functional Regulation

Single-Molecule Identification of the Conformations of Human C-Reactive Protein and Its Aptamer Complex with Solid-State Nanopores

(2022) Ji Wu et al.   ACS Applied Materials & Interfaces

Recent advances of cell surface modification based on aptamers

(2022) H.-R. Jia et al.   Materials Today Nano

Translation of aptamers toward clinical diagnosis and commercialization

(2022) Shan Liu et al.   BIOSENSORS & BIOELECTRONICS

Organ-on-a-Chip: The Future of Therapeutic Aptamer Research?

(2021) Thoa Thi Thanh Tran et al.   BioChip Journal

Mechanochemical bond scission for the activation of drugs

(2021) Shuaidong Huo et al.   Nature Chemistry

Inside Back Cover: Aptamer Blocking Strategy Inhibits SARS‐CoV‐2 Virus Infection (Angew. Chem. Int. Ed. 18/2021)

(2021) Miao Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activation of the Catalytic Activity of Thrombin for Fibrin Formation by Ultrasound

(2021) Pengkun Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis of Binding Modes of Antigen–Antibody Complexes by Molecular Mechanics Calculation

(2021) Liang Qu et al.   Journal of Chemical Information and Modeling

Genetic Code Expansion: Inception, Development, Commercialization

(2021) Miglena Manandhar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conversion of RNA Aptamer into Modified DNA Aptamers Provides for Prolonged Stability and Enhanced Antitumor Activity

(2021) Paola Amero et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-Templated Glycan Labeling for Monitoring Receptor Spatial Distribution in Living Cells

(2021) Wen Yang et al.   ANALYTICAL CHEMISTRY

Identification and Affinity Determination of Protein-Antibody and Protein-Aptamer Epitopes by Biosensor-Mass Spectrometry Combination

(2021) Loredana-Mirela Lupu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Engineered aptamer for the analysis of cells

(2021) Xiaochen Tang et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

DNA aptamer S11e recognizes fibrosarcoma and acts as a tumor suppressor

(2021) Yunyi Liu et al.   Bioactive Materials

Advanced Near‐Infrared Light for Monitoring and Modulating the Spatiotemporal Dynamics of Cell Functions in Living Systems

(2020) Guangcun Chen et al.   Advanced Science

Recent Progress in Aptamer Discoveries and Modifications for Therapeutic Applications

(2020) Shuaijian Ni et al.   ACS Applied Materials & Interfaces

Aptamer-Directed Protein-Specific Multiple Modifications of Membrane Glycoproteins on Living Cells

(2020) Xigao Chen et al.   ACS Applied Materials & Interfaces

G-quadruplex-based aptamers targeting human thrombin: Discovery, chemical modifications and antithrombotic effects

(2020) Claudia Riccardi et al.   PHARMACOLOGY & THERAPEUTICS

Evolution of a highly functional circular DNA aptamer in serum

(2020) Yu Mao et al.   NUCLEIC ACIDS RESEARCH

Scan and Unlock: A programmable DNA molecular automaton for cell‐selective activation of ligand‐based signaling

(2020) Jinghui Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Near-Infrared Light-Activated DNA-Agonist Nanodevice for Nongenetically and Remotely Controlled Cellular Signaling and Behaviors in Live Animals

(2019) Miao Wang et al.   NANO LETTERS

Stable, Wavelength-Tunable Fluorescent Dyes in the NIR-II Region for In Vivo High-Contrast Bioimaging and Multiplexed Biosensing

(2019) Zuhai Lei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Glue that Spatiotemporally Turns on Protein–Protein Interactions

(2019) Rina Mogaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequence-selective minor groove recognition of a DNA duplex containing synthetic genetic components

(2019) Giacomo Padroni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TRAIL-inspired multivalent dextran conjugates efficiently induce apoptosis upon DR5 receptor clustering

(2019) Hendrik Schneider et al.   CHEMBIOCHEM

Engineering Cell Surface Receptor with DNA Nanotechnology for Cell Manipulation

(2019) JiaHui Fan et al.   CHEMBIOCHEM

Rational Design of Nanocarriers for Intracellular Protein Delivery

(2019) Xiaofei Qin et al.   ADVANCED MATERIALS

Bispecific Aptamer Induced Artificial Protein-Pairing: A Strategy for Selective Inhibition of Receptor Function

(2019) Liping Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In vivo molecular imaging for immunotherapy using ultra-bright near-infrared-IIb rare-earth nanoparticles

(2019) Yeteng Zhong et al.   NATURE BIOTECHNOLOGY

Development of a Monomeric Inhibitory RNA Aptamer Specific for FGFR3 that Acts as an Activator When Dimerized

(2019) Nachiket Kamatkar et al.   Molecular Therapy-Nucleic Acids

Ligand-Guided Selection with Artificially Expanded Genetic Information Systems against TCR-CD3ε

(2019) Hasan Zumrut et al.   BIOCHEMISTRY

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers

(2018) Miguel M. Lino et al.   ACS Nano

SDA and IDA – Two aptamers to inhibit cancer cell adhesion

(2018) Ulrich Hahn   BIOCHIMIE

Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters

(2018) Ying-Fang Fan et al.   CANCER LETTERS

Modulation of BACE1 Activity by Chemically Modified Aptamers

(2018) Cécile Gasse et al.   CHEMBIOCHEM

Signalling from the periphery to the brain that regulates energy homeostasis

(2018) Ki-Suk Kim et al.   NATURE REVIEWS NEUROSCIENCE

Near-infrared triggered strand displacement amplification for MicroRNA quantitative detection in single living cells

(2018) Wenhao Dai et al.   Chemical Science

SELEX methods on the road to protein targeting with nucleic acid aptamers

(2018) Payam Bayat et al.   BIOCHIMIE

Light-induced activation of c-Met signalling by photocontrolled DNA assembly

(2018) Shan Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Imaging of Receptor Dimers in Zebrafish and Living Cells via Aptamer Recognition and Proximity-Induced Hybridization Chain Reaction

(2018) Liping Wang et al.   ANALYTICAL CHEMISTRY

Regulation of Protein Activity and Cellular Functions Mediated by Molecularly Evolved Nucleic Acids

(2018) Jie Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Emerging Applications of Nanotechnology for Controlling Cell-Surface Receptor Clustering

(2018) Kaixiang Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enhanced Targeted Gene Transduction: AAV2 Vectors Conjugated to Multiple Aptamers via Reducible Disulfide Linkages

(2017) Yuan Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Circular Bivalent Aptamers Enable in Vivo Stability and Recognition

(2017) Hailan Kuai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polypharmacology-based ceritinib repurposing using integrated functional proteomics

(2017) Brent M Kuenzi et al.   Nature Chemical Biology

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

(2017) Weixin Tang et al.   Nature Communications

Near-infrared fluorophores for biomedical imaging

(2017) Guosong Hong et al.   Nature Biomedical Engineering

Thermo-Controlled in Situ Phase Transition of Polymer–Peptides on Cell Surfaces for High-Performance Proliferative Inhibition

(2016) Sheng-Lin Qiao et al.   ACS Applied Materials & Interfaces

Molecularly Imprinted Polymers with DNA Aptamer Fragments as Macromonomers

(2016) Zijie Zhang et al.   ACS Applied Materials & Interfaces

Ligand-guided selection of aptamers against T-cell Receptor-cluster of differentiation 3 (TCR-CD3) expressed on Jurkat.E6 cells

(2016) Hasan E. Zumrut et al.   ANALYTICAL BIOCHEMISTRY

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor

(2016) Alem W Kahsai et al.   Nature Chemical Biology

Chemically induced dimerization: reversible and spatiotemporal control of protein function in cells

(2015) Stephanie Voß et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Evolution of Functional Six-Nucleotide DNA

(2015) Liqin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein Activity Regulation: Inhibition by Closed-Loop Aptamer-Based Structures and Restoration by Near-IR Stimulation

(2015) Jie Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor

(2015) Thale C. Jarvis et al.   STRUCTURE

Improved Ligand Binding by Antibody–Aptamer Pincers

(2014) Sungmuk Kang et al.   BIOCONJUGATE CHEMISTRY

Optogenetic control of signaling in mammalian cells

(2014) Hannes M. Beyer et al.   Biotechnology Journal

Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand

(2014) Amy D. Gelinas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Activation of Receptor Tyrosine Kinases: Monomers or Dimers

(2014) Ichiro Maruyama   Cells

Optogenetic pharmacology for control of native neuronal signaling proteins

(2013) Richard H Kramer et al.   NATURE NEUROSCIENCE

In vitro selection with artificial expanded genetic information systems

(2013) K. Sefah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A magnetic switch for the control of cell death signalling in in vitro and in vivo systems

(2012) Mi Hyeon Cho et al.   NATURE MATERIALS

Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer

(2012) Domenica Musumeci et al.   PHARMACOLOGY & THERAPEUTICS

Gold Nanoparticles Presenting Hybridized Self-Assembled Aptamers That Exhibit Enhanced Inhibition of Thrombin

(2011) Yen-Chun Shiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein localization in disease and therapy

(2011) M.-C. Hung et al.   JOURNAL OF CELL SCIENCE

Aptamer-Conjugated Nanoparticles Efficiently Control the Activity of Thrombin

(2010) Yen-Chun Shiang et al.   ADVANCED FUNCTIONAL MATERIALS

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrated microfluidic system for rapid screening of CRP aptamers utilizing systematic evolution of ligands by exponential enrichment (SELEX)

(2009) Chao-June Huang et al.   BIOSENSORS & BIOELECTRONICS

Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart

(2009) J. D. Scott et al.   SCIENCE

Crystal structure of an RNA aptamer bound to thrombin

(2008) S. B. Long et al.   RNA

Optical Switches for Remote and Noninvasive Control of Cell Signaling

(2008) P. Gorostiza et al.   SCIENCE