ALYREF, a novel factor involved in breast carcinogenesis, acts through transcriptional and post-transcriptional mechanisms selectively regulating the short NEAT1 isoform

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ALYREF Drives Cancer Cell Proliferation Through an ALYREF-MYC Positive Feedback Loop in Glioblastoma

(2021) Jianjun Wang et al.   OncoTargets and Therapy

TNMplot.com: A Web Tool for the Comparison of Gene Expression in Normal, Tumor and Metastatic Tissues

(2021) Áron Bartha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability

(2021) Zsuzsanna Nagy et al.   Nature Communications

First-line atezolizumab plus nab-paclitaxel for unresectable, locally advanced, or metastatic triple-negative breast cancer: IMpassion130 final overall survival analysis

(2021) L.A. Emens et al.   ANNALS OF ONCOLOGY

PARP inhibitor sensitivity in BRCA-related metastatic breast cancer: an OlympiAD later

(2021) J. Fuentes-Antrás et al.   ANNALS OF ONCOLOGY

Long non-coding RNA NEAT1 confers oncogenic role in triple-negative breast cancer through modulating chemoresistance and cancer stemness

(2019) Vivian Yvonne Shin et al.   Cell Death & Disease

Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer

(2019) Aditya Bardia et al.   NEW ENGLAND JOURNAL OF MEDICINE

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

(2019) Xin Chen et al.   NATURE CELL BIOLOGY

The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts

(2018) Toomas Silla et al.   Cell Reports

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

(2018) Mathias Munschauer et al.   NATURE

Genome-wide screening of NEAT1 regulators reveals cross-regulation between paraspeckles and mitochondria

(2018) Yang Wang et al.   NATURE CELL BIOLOGY

Involvement of the long noncoding RNA NEAT1 in carcinogenesis

(2018) Christiane Klec et al.   Molecular Oncology

The lncRNA NEAT1 facilitates cell growth and invasion via the miR-211/HMGA2 axis in breast cancer

(2017) Xuerui Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

ALYREF mainly binds to the 5′ and the 3′ regions of the mRNA in vivo

(2017) Min Shi et al.   NUCLEIC ACIDS RESEARCH

CPSF6 is a Clinically Relevant Breast Cancer Vulnerability Target

(2017) Najat Binothman et al.   EBioMedicine

Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress

(2017) Stefanie Menges et al.   Scientific Reports

Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis

(2016) Pang-Kuo Lo et al.   Oncotarget

Erratum: Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

(2015) H Choudhry et al.   ONCOGENE

Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion

(2015) Dayana B. Rivadeneira et al.   Science Signaling

Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion

(2015) Dayana B. Rivadeneira et al.   Science Signaling

Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients

(2014) Paola Parrella et al.   Molecular Cancer

Alternative 3′-end processing of long noncoding RNA initiates construction of nuclear paraspeckles

(2012) Takao Naganuma et al.   EMBO JOURNAL

ALY as a potential contributor to metastasis in human oral squamous cell carcinoma

(2012) Yasuhiro Saito et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export

(2012) Nicolas Viphakone et al.   Nature Communications

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers

(2011) María S Domínguez-Sánchez et al.   BMC CANCER

Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX

(2011) María S. Domínguez-Sánchez et al.   PLoS Genetics

Triple-Negative Breast Cancer

(2010) Shaheenah Dawood   DRUGS

Mitochondrial shape changes: orchestrating cell pathophysiology

(2010) Silvia Campello et al.   EMBO REPORTS

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY

(2008) M. Okada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA