Prediction of Clearance in Neonates and Infants (≤ 3 Months of Age) for Drugs That Are Glucuronidated: A Comparative Study Between Allometric Scaling and Physiologically Based Pharmacokinetic Modeling

A Physiologically Based Pharmacokinetic Model to Describe Artemether Pharmacokinetics in Adult and Pediatric Patients

(2016) Wen Lin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Mechanistic versus allometric models for the prediction of drug clearance in neonates (

(2015) Iftekhar Mahmood   JOURNAL OF CLINICAL PHARMACOLOGY

Prediction of Drug Clearance in Premature and Mature Neonates, Infants, and Children ≤2 Years of Age: A Comparison of the Predictive Performance of 4 Allometric Models

(2015) Iftekhar Mahmood   JOURNAL OF CLINICAL PHARMACOLOGY

Prediction of Drug Clearance in Children: an Evaluation of the Predictive Performance of Several Models

(2014) Iftekhar Mahmood et al.   AAPS Journal

Prediction of glucuronidated drug clearance in pediatrics (≤5 years): An allometric approach

(2014) Iftekhar Mahmood   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

The allometric exponent for scaling clearance varies with age: a study on seven propofol datasets ranging from preterm neonates to adults

(2013) Chenguang Wang et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Developmental Changes in Morphine Clearance Across the Entire Paediatric Age Range are Best Described by a Bodyweight-Dependent Exponent Model

(2013) Chenguang Wang et al.   CLINICAL DRUG INVESTIGATION

The Integration of Allometry and Virtual Populations to Predict Clearance and Clearance Variability in Pediatric Populations over the Age of 6 Years

(2013) Andrea N. Edginton et al.   CLINICAL PHARMACOKINETICS

Adolescent Dosing and Labeling Since the Food and Drug Administration Amendments Act of 2007

(2013) Jeremiah D. Momper et al.   JAMA Pediatrics

Body Weight-Dependent Pharmacokinetics of Busulfan in Paediatric Haematopoietic Stem Cell Transplantation Patients

(2012) Imke H. Bartelink et al.   CLINICAL PHARMACOKINETICS

A Bodyweight-Dependent Allometric Exponent for Scaling Clearance Across the Human Life-Span

(2012) Chenguang Wang et al.   PHARMACEUTICAL RESEARCH

Whole body physiologically-based pharmacokinetic models: their use in clinical drug development

(2008) Andrea N Edginton et al.   Expert Opinion on Drug Metabolism & Toxicology