Manganese-enhanced magnetic resonance imaging method detects age-related impairments in axonal transport in mice and attenuation of the impairments by a microtubule-stabilizing compound

Multifunctional compounds lithium chloride and methylene Blue attenuate the negative effects of diisopropylfluorophosphate on axonal transport in rat cortical neurons

(2020) Sean X Naughton et al.   TOXICOLOGY

Age-Related Olfactory Dysfunction: Epidemiology, Pathophysiology, and Clinical Management

(2020) Kenji Kondo et al.   Frontiers in Aging Neuroscience

Ageing as a risk factor for neurodegenerative disease

(2019) Yujun Hou et al.   Nature Reviews Neurology

Axonal transport and neurological disease

(2019) James N. Sleigh et al.   Nature Reviews Neurology

Temporal Control of Axonal Transport: The Extreme Case of Organismal Ageing

(2019) Francesca Mattedi et al.   Frontiers in Cellular Neuroscience

Repeated exposures to diisopropylfluorophosphate result in structural disruptions of myelinated axons and persistent impairments of axonal transport in the brains of rats

(2018) Sean X. Naughton et al.   TOXICOLOGY

A Study of Small RNAs from Cerebral Neocortex of Pathology-Verified Alzheimer's Disease, Dementia with Lewy Bodies, Hippocampal Sclerosis, Frontotemporal Lobar Dementia, and Non-Demented Human Controls

(2018) Sébastien S. Hébert et al.   JOURNAL OF ALZHEIMERS DISEASE

Repositioning Microtubule Stabilizing Drugs for Brain Disorders

(2018) Artemis Varidaki et al.   Frontiers in Cellular Neuroscience

Translating the biology of aging into novel therapeutics for Alzheimer disease

(2018) Yuko Hara et al.   NEUROLOGY

Microtubules in health and degenerative disease of the nervous system

(2016) Andrew J. Matamoros et al.   BRAIN RESEARCH BULLETIN

Stability properties of neuronal microtubules

(2016) Peter W. Baas et al.   Cytoskeleton

Olfaction and Aging: A Mini-Review

(2015) Johannes Attems et al.   GERONTOLOGY

The microtubule-stabilizing drug Epothilone D increases axonal sprouting following transection injury in vitro

(2015) Mariana Brizuela et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Axonal transport declines with age in two distinct phases separated by a period of relative stability

(2015) Stefan Milde et al.   NEUROBIOLOGY OF AGING

Repeated exposure to chlorpyrifos leads to prolonged impairments of axonal transport in the living rodent brain

(2015) Caterina M. Hernandez et al.   NEUROTOXICOLOGY

Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease

(2014) Kurt R. Brunden et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Axonal transport rate decreased at the onset of optic neuritis in EAE mice

(2014) Tsen-Hsuan Lin et al.   NEUROIMAGE

Neuronal transport defects of the MAP6 KO mouse – a model of schizophrenia – and alleviation by Epothilone D treatment, as observed using MEMRI

(2014) Alexia Daoust et al.   NEUROIMAGE

In vivo axonal transport deficits in a mouse model of fronto-temporal dementia

(2014) Tabassum Majid et al.   NeuroImage-Clinical

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

Microtubule Alterations Occur Early in Experimental Parkinsonism and The Microtubule Stabilizer Epothilone D Is Neuroprotective

(2013) Daniele Cartelli et al.   Scientific Reports

Both chronic treatments by epothilone D and fluoxetine increase the short-term memory and differentially alter the mood status of STOP/MAP6 KO mice

(2012) Vincent Fournet et al.   JOURNAL OF NEUROCHEMISTRY

The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice

(2012) B. Zhang et al.   JOURNAL OF NEUROSCIENCE

A New Link to Mitochondrial Impairment in Tauopathies

(2012) Kathrin L. Schulz et al.   MOLECULAR NEUROBIOLOGY

Review: Axon pathology in age-related neurodegenerative disorders

(2012) R. Adalbert et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Quantitative in vivo measurement of early axonal transport deficits in a triple transgenic mouse model of Alzheimer's disease using manganese-enhanced MRI

(2011) Jieun Kim et al.   NEUROIMAGE

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

(2010) Sébastien S. Hébert et al.   HUMAN MOLECULAR GENETICS

Selective Lesions by Manganese and Extensive Damage by Iron After Injection into Rat Striatum or Hippocampus

(2010) W. N. Sloot et al.   JOURNAL OF NEUROCHEMISTRY

Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy

(2010) K. R. Brunden et al.   JOURNAL OF NEUROSCIENCE

Influence of aging on peripheral nerve function and regeneration

(2010) Enrique Verdú et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

R-flurbiprofen improves axonal transport in the Tg2576 mouse model of Alzheimer's Disease as determined by MEMRI

(2010) Karen D. B. Smith et al.   MAGNETIC RESONANCE IN MEDICINE

Altered Neurocircuitry in the Dopamine Transporter Knockout Mouse Brain

(2010) Xiaowei Zhang et al.   PLoS One

Long-term survival of olfactory sensory neurons after target depletion

(2009) Krista Sultan-Styne et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Reward circuitry is perturbed in the absence of the serotonin transporter

(2009) Elaine L. Bearer et al.   NEUROIMAGE

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Age-related decrease in axonal transport measured by MR imaging in vivo

(2007) Donna J. Cross et al.   NEUROIMAGE