Article
Chemistry, Physical
Jacob Schneidewind
Summary: This article introduces an open-source software and modeling method for techno-economic analysis of technologies such as photoelectrochemical, photocatalytic, and photovoltaic + electrolysis, to determine the required technological improvements to achieve cost competitiveness. It explores the necessary progress for each technology and proposes actionable research targets.
ADVANCED ENERGY MATERIALS
(2022)
Article
Computer Science, Hardware & Architecture
Lei Zhang, Hao Xu, Oluwakayode Onireti, Muhammad Ali Imran, Bin Cao
Summary: This article introduces wireless blockchain networks (WBN) under various commonly used consensus mechanisms and discusses the impact of communication resources on blockchain performance. Analytical and simulated results are provided to show how communication resource provision affects blockchain performance.
Article
Computer Science, Interdisciplinary Applications
Junhao Hu, Chenyang Zhang, Kang Zhou, Shenghua Gao
Summary: Chest X-ray is an important imaging method for diagnosing chest diseases. We propose a semantic-segmentation-based solution for chest X-ray diagnostic quality assessment and create a dataset to validate it. Our experiments validate the effectiveness of our solution.
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2022)
Article
Environmental Studies
Jonas Kathage, Bert Smit, Bas Janssens, Wiepie Haagsma, Jose Luis Adrados
Summary: EU agriculture is under increasing pressure to support environmental protection and climate change mitigation. Catch and cover crops, an underused farming practice, have the potential to contribute towards these goals. However, adoption rates vary widely between regions and are influenced predominantly by policy rather than environmental or climate change considerations. Non-adopters may be more likely to adopt if stronger policy obligations or additional subsidies are implemented.
Editorial Material
Multidisciplinary Sciences
Ira Leifer
Summary: The extent of human-caused marine oil pollution is much more significant than previously believed.
Article
Clinical Neurology
Malco Rossi, Santiago Perez-Lloret, Marcelo Merello
Summary: The study found that in a clinical setting, the time needed to reach a final clinical diagnosis for patients presenting with parkinsonism and/or tremor was 2.75 years. Patients with a positive response to levodopa challenge (LDC) benefited from shorter delays until the final clinical diagnosis (FCD).
PARKINSONISM & RELATED DISORDERS
(2021)
Article
Chemistry, Physical
Moritz Schneider, Daniel Born, Johannes Kaestner, Guntram Rauhut
Summary: The positions of grid points have a significant impact on the accuracy and computational effort of a multidimensional potential energy surface (PES) represented by n-mode expansions. Six different positioning schemes were studied, including a static approach and five adaptive schemes based on Gaussian process regression. Comparison with a more sophisticated approach by Christiansen et al. was made. The impact of grid point positions on multilevel PESs was discussed with respect to computational effort.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Review
Oncology
Safia K. Ahmed, Ivy A. Petersen
Summary: Preoperative radiation therapy is an important component of curative treatment for soft tissue sarcomas, and innovative strategies have been developed to individualize the treatment approach.
CURRENT TREATMENT OPTIONS IN ONCOLOGY
(2022)
Article
Energy & Fuels
Christoph Heilmann, David Wozabal
Summary: This paper explores how smart-charging of PEVs can mitigate challenges presented by VRES expansion and reduce distribution grid costs. A heuristic policy is proposed for Germany in 2035, leading to potential savings of €6.2 billion and a 19% reduction in total costs. The potential of smart charging is higher in rural areas than urban centers, and curtailing VRES production is only economically viable in rare circumstances.
Article
Psychology, Multidisciplinary
Ismail Xodabande, Hourieh Ebrahimi, Sedigheh Karimpour
Summary: This study reveals that a vocabulary knowledge of 5000 most frequent English words is needed to cover the course contents of MOOCs, while achieving adequate coverage level requires a vocabulary size of around 9000 most frequent English words. Widely used word lists for general and academic vocabulary are found to be insufficient for MOOC learners.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Oncology
Leiah J. Brigitha, Rob Pieters, Inge M. van der Sluis
Summary: This review evaluates the optimal amount of asparaginase needed for childhood ALL treatment outcomes. While the level of exposure does not impact the outcome as long as therapeutic asparaginase activity levels are reached, the duration of exposure does have an effect on the outcome, with no clear cutoff for optimal exposure duration established. Other factors such as immunophenotype, (cyto)genetic subgroups, risk group stratification, and backbone therapy also influence the optimal exposure duration.
EUROPEAN JOURNAL OF CANCER
(2021)
Article
Surgery
Rickesha Wilson, Sayf A. Said, Susan Rydzinski, Jesse Gutnick, Ali Aminian, Toms Augustin
Summary: This study evaluates the outcomes of maximal opioid reduction on top of an existing Enhanced Recovery after Surgery (ERAS) pathway in a bariatric surgery program. The results indicate that implementing an opioid-sparing protocol not only reduces opioid use in surgical patients, but also improves satisfaction with pain control.
SURGERY FOR OBESITY AND RELATED DISEASES
(2023)
Editorial Material
Hematology
Charles T. Quinn
Summary: In this study, Abdullahi et al provide evidence that fixed low- and moderate-dose daily hydroxyurea regimens can be effective in preventing secondary stroke for patients with sickle cell anemia living in low-resource settings, as an alternative to chronic transfusion therapy.
Article
Ecology
Stephanie Tomscha, Bethanna Jackson, Rubianca Benavidez, Mairead de Roiste, Stephen Hartley, Julie Deslippe
Summary: Percentage-based targets for conservation and restoration lack evidence, especially for multiple ecosystem services. Decision-making scales can also pose challenges for implementing restoration targets. This study examined these challenges in the Ruamahanga Basin, New Zealand, where most wetlands have been drained. Restoration scenarios were created at two spatial scales: basin-scale and subcatchment-scale. The results showed that most of the variability in ecosystem service outcomes is found at fine spatial scales, which has implications for policy mechanisms and spatially-targeted management of ecosystem services.
ECOSYSTEM SERVICES
(2023)
Article
Biodiversity Conservation
Elwyn Sharps, Robert W. Hawkes, Andrew J. Bladon, David L. Buckingham, Jennifer Border, Antony J. Morris, Philip V. Grice, Will J. Peach
Summary: Agri-environment schemes (AES) are the primary policy mechanism for addressing farmland biodiversity declines across Europe. Higher-tier AES provision can promote avian population growth on farmland, while lower-tier provision has less impact. To increase regional farmland bird populations by 10%, 47% and 26% of the farmed landscape would need to be devoted to higher-tier agreements in arable and pastoral landscapes, respectively.
JOURNAL OF APPLIED ECOLOGY
(2023)
Article
Medicine, General & Internal
Hongchao Pan, Richard Gray, Jeremy Braybrooke, Christina Davies, Carolyn Taylor, Paul McGale, Richard Peto, Kathleen I. Pritchard, Jonas Bergh, Mitch Dowsett, Daniel F. Hayes
NEW ENGLAND JOURNAL OF MEDICINE
(2017)
Editorial Material
Geriatrics & Gerontology
P. Dovjak
ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE
(2018)
Meeting Abstract
Oncology
Jennifer A. Ligibel, William Thomas Barry, Catherine M. Alfano, Dawn L. Hershman, Melinda L. Irwin, Marian Neuhouser, Cynthia A. Thomson, Linda Delahanty, Elizabeth Frank, Patricia Spears, Electra D. Paskett, Judith O. Hopkins, Vanessa Bernstein, Vered Stearns, Julia R. White, Thomas Wadden, Pamela Jean Goodwin, Lisa A. Carey, Ann Partridge, Eric P. Winer
JOURNAL OF CLINICAL ONCOLOGY
(2018)
Meeting Abstract
Oncology
Isabel Pimentel, Bingshu E. Chen, Ana Elisa Lohmann, Marguerite Ennis, Jennifer A. Ligibel, Lois E. Shepherd, Dawn L. Hershman, Vuk Stambolic, Ingrid A. Mayer, Timothy J. Hobday, Julie Lemieux, Alastair Mark Thompson, Priya Rastogi, Karen A. Gelmon, Timothy Joseph Whelan, Manuela Rabaglio-Poretti, Ryan Jo Dowling, Wendy R. Parulekar, Pamela Jean Goodwin
JOURNAL OF CLINICAL ONCOLOGY
(2019)
Editorial Material
Oncology
Ana Elisa Lohmann, Pamela J. Goodwin
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Editorial Material
Oncology
Pamela J. Goodwin
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Article
Oncology
Pamela J. Goodwin, Ryan J. O. Dowling, Marguerite Ennis, Bingshu E. Chen, Wendy R. Parulekar, Lois E. Shepherd, Margot J. Burnell, Rachel Vander Meer, Andrea Molckovsky, Anagha Gurjal, Karen A. Gelmon, Jennifer A. Ligibel, Dawn L. Hershman, Ingrid A. Mayer, Timothy J. Whelan, Timothy J. Hobday, Priya Rastogi, Manuela Rabaglio-Poretti, Julie Lemieux, Alastair M. Thompson, Daniel W. Rea, Vuk Stambolic
Summary: The study demonstrates that metformin compared to placebo leads to significant weight and metabolic improvements in breast cancer patients, with no influence from baseline BMI or insulin, and no differences based on the rs11212617 allele status.
Article
Oncology
Martin C. Chang, Zohreh Eslami, Marguerite Ennis, Pamela J. Goodwin
Summary: Crown-like structures of the breast (CLS-B) are positively correlated with older age, obesity, dyslipidemia, and higher levels of metabolic factors, while different methods of detecting CLS-B show different associations with metabolic factors, disease-free survival, and overall survival. Further research is needed to understand the biological basis for these differences.
Article
Oncology
Ana Elisa Lohmann, Marguerite Ennis, Wendy R. Parulekar, Bingshu E. Chen, George Tomlinson, Pamela J. Goodwin
Summary: Interim analysis plays a role in terminating exposure to ineffective or unsafe drugs while identifying effective treatments. However, in breast cancer treatment, early analysis may overlook the effects that can only be observed with longer follow-up.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2022)
Editorial Material
Oncology
Pamela J. Goodwin
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Meeting Abstract
Oncology
Dawn L. Hershman, Bingshu E. Chen, Wendy R. Parulekar, Julie Lemieux, Jennifer A. Ligibel, Karen A. Gelmon, Timothy Joseph Whelan, Pamela Jean Goodwin
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Oncology
Pamela J. Goodwin, Ryan J. O. Dowling, Marguerite Ennis, Bingshu E. Chen, Wendy R. Parulekar, Lois E. Shepherd, Karen A. Gelmon, Timothy J. Whelan, Jennifer A. Ligibel, Dawn L. Hershman, Ingrid A. Mayer, Timothy J. Hobday, Priya Rastogi, Manuela Rabaglio-Poretti, Julie Lemieux, Alastair M. Thompson, Daniel W. Rea, Vuk Stambolic
Summary: The study showed that metformin significantly reduces CA 15-3 levels in early-stage breast cancer patients. This reduction is independent of tumor characteristics and treatment methods.
JNCI CANCER SPECTRUM
(2021)
Article
Oncology
Pamela J. Goodwin, Roanne J. Segal, Michael Vallis, Jennifer A. Ligibel, Gregory R. Pond, Andre Robidoux, Brian Findlay, Julie R. Gralow, Som D. Mukherjee, Mark Levine, Kathleen I. Pritchard
Meeting Abstract
Oncology
Ana Elisa Lohmann, Sara V. Soldera, Isabel Pimentel, Domen Ribnikar, Marguerite Ennis, Eitan Amir, Pamela Jean Goodwin
JOURNAL OF CLINICAL ONCOLOGY
(2019)
Meeting Abstract
Medicine, Research & Experimental
Blerta Starova, Mandi Rahimi, Marguerite Ennis, Ryan J. O. Dowling, Vuk Stambolic, Pamela J. Goodwin, Martin C. Chang
LABORATORY INVESTIGATION
(2017)
