Nanoparticulate DNA scavenger loading methotrexate targets articular inflammation to enhance rheumatoid arthritis treatment

TGF-β blockade-improved chemo-immunotherapy with pH/ROS cascade-responsive micelle via tumor microenvironment remodeling

(2021) Liangliang Dai et al.   BIOMATERIALS

The protein corona modulates the inflammation inhibition by cationic nanoparticles via cell-free DNA scavenging

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Cationic Block Copolymer Nanoparticles with Tunable DNA Affinity for Treating Rheumatoid Arthritis

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Modular Acid-Activatable Acetone-Based Ketal-Linked Nanomedicine by Dexamethasone Prodrugs for Enhanced Anti-Rheumatoid Arthritis with Low Side Effects

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Identification of Specific Joint-Inflammatogenic Cell-Free DNA Molecules From Synovial Fluids of Patients With Rheumatoid Arthritis

(2020) Cong Dong et al.   Frontiers in Immunology

Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization

(2020) Yihua Yang et al.   BIOMATERIALS

Tuned Cationic Dendronized Polymer: Molecular Scavenger for Rheumatoid Arthritis Treatment

(2019) Bo Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Effect of short-term methotrexate discontinuation on rheumatoid arthritis disease activity: post-hoc analysis of two randomized trials

(2019) Jin Kyun Park et al.   CLINICAL RHEUMATOLOGY

Engineering nanoparticles for targeting rheumatoid arthritis: Past, present, and future trends

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Comparison of combination therapy with methotrexate and sinomenine or leflunomide for active rheumatoid arthritis: a randomized controlled clinical trial

(2018) Run-yue Huang et al.   PHYTOMEDICINE

Cationic nanoparticle as an inhibitor of cell-free DNA-induced inflammation

(2018) Huiyi Liang et al.   Nature Communications

Investigating methotrexate toxicity within a randomized double-blinded, placebo-controlled trial: Rationale and design of the Cardiovascular Inflammation Reduction Trial-Adverse Events (CIRT-AE) Study

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Recent advances in nanomedicines for the treatment of rheumatoid arthritis

(2017) Qin Wang et al.   Biomaterials Science

Utilization of nanoparticle technology in rheumatoid arthritis treatment

(2016) Sanam Dolati et al.   BIOMEDICINE & PHARMACOTHERAPY

Rheumatoid arthritis

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Principles of nanoparticle design for overcoming biological barriers to drug delivery

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Enzyme-Degradable Self-Assembled Nanostructures from Polymer–Peptide Hybrids

(2014) Daniel Bacinello et al.   BIOMACROMOLECULES

Enzymatic, physicochemical and biological properties of MMP-sensitive alginate hydrogels

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Clinical pharmacogenetic model to predict response of MTX monotherapy in patients with established rheumatoid arthritis after DMARD failure

(2012) Jaap Fransen et al.   PHARMACOGENOMICS

Low-dose and high-dose methotrexate are two different drugs in practical terms

(2010) Anand N. MALAVIYA et al.   International Journal of Rheumatic Diseases

Grape Seed Extract Suppresses Lipopolysaccharide-Induced Matrix Metalloproteinase (MMP) Secretion by Macrophages and Inhibits Human MMP-1 and -9 Activities

(2009) Vu Dang La et al.   JOURNAL OF PERIODONTOLOGY

Efficacy and toxicity of methotrexate (MTX) monotherapy versus MTX combination therapy with non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and meta-analysis

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