Article
Materials Science, Multidisciplinary
Xi -Ping Mu, Tong Li, Fei-Fei Guo, Zhi-Hao Xu, Ping Sun, Xue Zhang, Tao Wang, Wei -Wei Gao, Ya-Mu Xia
Summary: Se nanoparticles-loaded and Mo-doped FePc nanorods (Se-Mo-FePc NRs) were successfully constructed. They can efficiently catalyze the generation of ·OH from endogenous H2O2 and show photodynamic performance under laser irradiation. Additionally, they possess good NIR photothermal conversion efficiency and exhibit excellent antibacterial efficiency with low hemolysis and cytotoxicity.
Article
Materials Science, Multidisciplinary
Xiaojing He, Shuo Rong, Yarong Jin, Ruiping Zhang
Summary: By binding Cu2+ with melanin to form a nanozyme, the near infrared light absorption and photothermal performance of melanin were significantly enhanced. The nanozyme exhibited excellent peroxidase-like catalytic activity, converting H2O2 into toxic hydroxyl radicals. The synergistic antibacterial effect achieved through the combination of nanozyme catalysis and enhanced photothermal property could effectively kill bacteria within only 5 minutes under 808 nm laser irradiation, which holds great potential for the design of antimicrobial materials.
Article
Materials Science, Multidisciplinary
Jie Feng, Fei Kong, Wan-Sheng Yue, Hao Yu, Zi-Liang He, Ya-Nan Zhai, Yu-Bin Dong
Summary: In this study, an H2O2-responsive nanozyme, ABTS@Fe-DhaTph, was developed for combination therapy of catalytic therapy, photothermal therapy, and photodynamic therapy. It can catalyze the decomposition of H2O2 to produce cytotoxic hydroxyl radicals for in situ tumor catalytic therapy. Additionally, it can enable H2O2-dependent photothermal therapy and synergistically enhance reactive oxygen species generation, thereby improving catalytic therapy and photodynamic therapy.
SCIENCE CHINA-MATERIALS
(2023)
Article
Chemistry, Medicinal
Xiaoqing Li, Yue Cao, Bo Xu, Ying Zhao, Tianqi Zhang, Yinghui Wang, Daguang Wang, Jianhua Liu, Shuyan Song, Hongjie Zhang
Summary: Novel nanocomposites were constructed by encapsulating Au nanoparticles and Ru nanoparticles into dendritic mesoporous silica. These nanocomposites exhibit cascade catalytic ability and good photothermal performance, showing improved effects through synergistic therapy in cancer treatment.
Article
Chemistry, Physical
Yiming Ding, Zhuo Wang, Zeyu Zhang, Yunchao Zhao, Shangyu Yang, Yalong Zhang, Shuncheng Yao, Shaobo Wang, Tian Huang, Yang Zhang, Linlin Li
Summary: With the development of nanomaterials, photothermal therapy and photodynamic therapy have become new options for cancer treatment. In this study, oxygen vacancy-engineered BaTiO3 nanoparticles were used for near-infrared light-triggered therapy, resulting in improved cancer treatment efficacy. The multifunctional nanoplatform achieved high therapeutic efficacy with a single near-infrared light irradiation.
Article
Engineering, Environmental
Feng Wei, Xinyu Cui, Zhao Wang, Changchang Dong, Jiadong Li, Xiaojun Han
Summary: The study successfully demonstrated the efficient antibacterial performance of Fe3O4@MoS2-Ag nanozyme against E. coli, and revealed a synergistic disinfection effect. Through the collaborative work of peroxidase-like activity, photothermal effect, and Ag+ leakage, the nanozyme could accurately and rapidly attack bacterial membranes, showing broad-spectrum antibacterial capabilities.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Biotechnology & Applied Microbiology
Chuan Liu, Xuanping Zhao, Zichao Wang, Yingyuan Zhao, Ruifang Li, Xuyang Chen, Hong Chen, Mengna Wan, Xueqin Wang
Summary: This study reports an innovative hybrid nanozyme independent of antibiotics for antimicrobial wound healing, which showed excellent biocompatibility and antibacterial effects, making it a potential strategy for healing bacterial wound infections.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Materials Science, Biomaterials
Meng-Chao Wang, Jing-Xuan Guo, Li-Jian Chen, Xu Zhao
Summary: The research team successfully developed a multifunctional porphyrin-COF for targeted bacteria and synergistic phototherapy/chemotherapy to achieve sterilization and wound healing. The ordered crystal structure of the porphyrin-COF effectively avoids fluorescence quenching and facilitates the storage and transport of singlet oxygen. The acrylate substituent in the COF serves as a bacterial targeting moiety and reacts with the bacterial surface protein, fixing the bacteria on the COF surface and inhibiting colonization. The bonding of COF and bacteria further enhances the therapeutic efficiency of phototherapy.
BIOMATERIALS SCIENCE
(2023)
Article
Biophysics
Zhaoyu Han, Yue Qian, Xiyue Gao, Dutao Yang, Yanfei Cai, Yun Chen, Jian Jin, Zhaoqi Yang
Summary: In recent years, laser-mediated photodynamic therapy and photothermal therapy have received significant attention due to their minimally invasive characteristics and high specificity. However, traditional photodynamic or photothermal therapy has certain limitations such as the hypoxic microenvironment and complex operation. This study developed a drug delivery system using covalent organic framework (COF) as a carrier for the photosensitizer indocyanine green (ICG) and the hypoxia-activating prodrug AQ4N, with hyaluronic acid (HA) modified on the surface of COF. The HA-COF@ICG/AQ4N system can target tumor cells through recognizing CD44, which is overexpressed in the surface of tumor cells membrane. Under the irradiation of a single NIR laser, the nanoplatform simultaneously produces a combined effect of photodynamic and photothermal, enhancing the antitumor effect.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Physical
Zhilong Xu, Jie Chen, Yanan Li, Ting Hu, Lei Fan, Juqun Xi, Jie Han, Rong Guo
Summary: Tumor treatments based on phototherapy show great promise, but their dependence on light poses limitations. In this study, we designed yolk-shell magnetic nanoparticles with multiple functionalities for tumor therapy. The results demonstrate the efficacy of the designed nanoparticles in inhibiting tumor growth both in vitro and in vivo.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Review
Medicine, Research & Experimental
Yanmei Zhang, Xin Hu, Jing Shang, Wenhui Shao, Liming Jin, Chunshan Quan, Jun Li
Summary: Pathogenic infections pose major threats to global public health due to the abuse of antibiotics and the resulting multidrug resistance. The development of novel, efficient, and biosafe antibiotic alternatives is urgently needed. Nanozymes have emerged as promising alternatives for combating bacterial infections, particularly through multimodal synergistic therapies that offer novel disinfection pathways.
Article
Chemistry, Applied
Bingyu Xu, Zhao Wang, Weimin Zhao
Summary: A novel photosensitizer aggregate has been designed and constructed, showing high photothermal conversion efficiency and good hydrophilia, suitable for both photodynamic therapy and photothermal therapy, resulting in superior antitumor performance. Additionally, the aggregate exhibits excellent biocompatibility and safety for biomedical applications.
Article
Chemistry, Multidisciplinary
Chong-Bo Ma, Yaping Xu, Lixin Wu, Quan Wang, Jia-Jia Zheng, Guoxi Ren, Xiaoyu Wang, Xingfa Gao, Ming Zhou, Ming Wang, Hui Wei
Summary: This study presents a facile synthetic strategy for a dual single-atom nanozyme composed of zinc (Zn) and molybdenum (Mo). The nanozyme utilizes polyoxometalates and supramolecular coordination complexes as metal-atom precursors, and an amphiphilic aerogel as the supporting substrate. The dual single-atoms of Zn and Mo exhibit a synergistic effect and peroxidase-like activity. The nanozyme shows outstanding stability and is capable of detecting various analytes in different samples.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Analytical
Liling Lu, Xuehan Hu, Ruijin Zeng, Qianyun Lin, Xue Huang, Meijin Li, Dianping Tang
Summary: This work reports a versatile dual-mode colorimetric and photothermal biosensing platform for acetylcholinesterase (AChE) detection and its inhibitor monitor based on Fe-N-C/H2O2/3,3',5,5'-tetramethylbenzidine (TMB) system. The platform shows outstanding sensitivity and selectivity, and can be easily extended for the detection of other biomolecules related to H2O2 generation or consumption.
ANALYTICA CHIMICA ACTA
(2022)
Article
Nanoscience & Nanotechnology
Sk Rajab Ali, Mrinmoy De
Summary: Nanozymes, specifically two-dimensional molybdenum disulfide (2D-MoS2) nanosheets, can enhance their peroxidase-like activity through surface functionalization, showing excellent antibacterial properties when combined with hydrogen peroxide (H2O2). Proper surface modification of nanomaterials with intrinsic nanozyme properties can lead to enhanced activity, with potential applications in disinfectants, biosensors, drug delivery, and more.
ACS APPLIED NANO MATERIALS
(2021)
Article
Engineering, Environmental
Li Zhang, Jia-Qi Fan, Qiong-Qing Zheng, Sai-Jin Xiao, Cheng-Rong Zhang, Shun-Mo Yi, Xin Liu, Wei Jiang, Quan-Gen Tan, Ru-Ping Liang, Jian-Ding Qiu
Summary: In this study, a two-dimensional mesoporous fluorescent covalent organic framework named TY-Hz COF was developed for simultaneous detection and recovery of Au(III). The TY-Hz COF showed rapid and sensitive response to Au(III) with electron transfer-induced fluorescence quenching and visual color change. Moreover, it exhibited excellent adsorption capacity and selectivity towards Au(III). These findings suggest that TY-Hz COF has great potential for Au(III) detection and recovery in e-waste.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Chemical
Wei-Rong Cui, Yi-Ru Chen, Wei Xu, Kai Liu, Wei-Bin Qiu, Yibao Li, Jian-Ding Qiu
Summary: A hydroxyl-functionalized 3D covalent organic framework (TAPM-DHBD) with strong fluorescence and 3D interconnected pore channels was synthesized and evaluated for uranium detection and extraction. TAPM-DHBD exhibited exceptional uranium extraction capacity and fast kinetics, with an ultra-low detection limit suitable for sensitive and on-site monitoring of radioactive uranium contamination. Furthermore, TAPM-DHBD showed excellent regenerable performance, providing a new strategy for radioactive contamination monitoring and strategic nuclides extraction.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Review
Chemistry, Analytical
Li Zhang, Quan-Gen Tan, Jia-Qi Fan, Chen Sun, Yu-Ting Luo, Ru-Ping Liang, Jian-Ding Qiu
Summary: Microfluidic techniques including CE, CEC, and MEKC have been widely used for the chiral separation of biomolecules. Different strategies are employed in these techniques, such as CS-bonded stationary phase in CEC, addition of CS to the mobile phase in CE, and involvement of chiral surfactants and/or CS in pseudostationary phases of MEKC. Microfluidic techniques offer advantages of high selectivity, excellent separation efficiency, and low cost compared to conventional techniques. This review discusses innovations in detection systems, separation mechanism, CS, and chiral analytes of biomolecules, as well as the most applied CSs and the chiral separation of representative biomolecules. Prospects and future developments of microfluidics for chiral separation are also proposed.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Chemical
Run-Han Yan, Wei-Rong Cui, Wei Jiang, Juan Huang, Ru-Ping Liang, Jian-Ding Qiu
Summary: In this work, a covalent polymeric network (Py-CPN) based on pyridinium was successfully designed and synthesized, which showed high efficiency and reliability in adsorbing radioactive 99TcO4. This research has significant implications for environmental protection.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Engineering, Environmental
Wei-Rong Cui, Wei Xu, Yi-Ru Chen, Kai Liu, Wei-Bin Qiu, Yibao Li, Jian-Ding Qiu
Summary: In this study, a novel olefin-linked cationic covalent organic framework (COF) BDBI-TMT was synthesized by integrating robust imidazolium salt-based linkers with triazine building blocks, which showed excellent stability in acid/base solutions and radiation. BDBI-TMT exhibited ultra-fast adsorption kinetics and high capture capacity for ReO4- (a non-radioactive surrogate of 99TcO4-), attributed to the abundance of precisely tailored imidazolium salt-based units and the hydrophobicity of the alkyl skeleton. The selective and reversible extraction of ReO4- under extreme conditions demonstrates the great potential of olefin-linked cationic COFs for radionuclide remediation.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Engineering, Environmental
Qing-Hua Hu, You-Gan Wang, Xin Gao, Yu-Zhen Shi, Sen Lin, Ru-Ping Liang, Jian-Ding Qiu
Summary: Researchers have successfully constructed two isostructural MOFs, NCU-3-X (X = Cl, Br), for efficient adsorption of ReO4-/TcO4- in nuclear waste. NCU-3-Br exhibited superior adsorption performances due to the smaller electronegativity of bromine atoms and the presence of one-dimensional hydrophobic channels in its framework. The adsorption capacity of NCU-3-Br to ReO4-/TcO4- was confirmed through experiments.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Engineering, Environmental
Xin Liu, Rui-Xiang Bi, Feng-Tao Yu, Cheng-Rong Zhang, Qiu-Xia Luo, Ru-Ping Liang, Jian-Ding Qiu
Summary: This study synthesized Bi4Ti3O12 (B1) particles, crosslinked B1 with 6-chloro-1,3,5-triazine-diamine (DCT) to obtain B2, and formed B3 using B2 and 4-formylbenzaldehyde (BA-CHO) to investigate its usefulness for photocatalytic UVI removal. B3, with the D-7E-A array structure, effectively reduced UVI to UIV due to energy level matching effects. The UVI removal capacity of B3 under simulated sunlight was 684.9 mg g-1, 2.5 times greater than B1 and 1.8 times greater than B2.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Engineering, Environmental
Xiao-Juan Chen, Cheng-Rong Zhang, Xin Liu, Jia-Xin Qi, Wei Jiang, Shun-Mo Yi, Cheng-Peng Niu, Yuan-Jun Cai, Ru-Ping Liang, Jian-Ding Qiu
Summary: Developing ideal adsorbents for efficient and fast uranium extraction has always been a challenge. In this study, a soft three-dimensional covalent organic framework (TAM-DHBD) with a fivefold interpenetrating structure was prepared as a novel porous platform for the efficient extraction of radioactive uranium. TAM-DHBD exhibited exceptional crystallinity, prominent porosity, and excellent chemical stability, allowing for high selectivity and rapid adsorption of uranium.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Engineering, Chemical
Zhenzhen Xu, Shanshan Yu, Jinyu Wang, Fengtao Yu, Mei Xu, Jianbo Xiong, Saijin Xiao, Yan Liu, Yan He, Jie Xu, Zhibin Zhang, Jianding Qiu
Summary: In this study, a molecular engineering strategy was used to simultaneously achieve high degree of functionalization and large BET in conjugated microporous polymers (CMPs) as an effective uranium adsorbent. The PePy-SO3H adsorbent, which contains a pyrene-based monomer with extended pi-conjugation degree and high rigidity, exhibited strong affinity toward uranium with a distribution coefficient of 2.3 x 104 mL g-1 and an exceptionally high adsorption capacity of 579.0 mg g-1. This work demonstrates the advantages of molecular engineering strategies in optimizing the purification performance of CMPs adsorbents for uranium-containing wastewater.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Engineering, Chemical
Xiao-Rong Chen, Cheng-Rong Zhang, Wei Jiang, Xin Liu, Qiu-Xia Luo, Li Zhang, Ru-Ping Liang, Jian-Ding Qiu
Summary: In this study, a novel three-dimensional cationic covalent organic framework (TFAM-BDNP) was designed and synthesized via Zincke reaction for the selective capture of TcO4-/ReO4-. TFAM-BDNP exhibited high adsorption capacity and extremely fast exchange kinetic for ReO4-, attributed to its open 3D hydrophobic channels, abundant active sites, and high chemical stability. Furthermore, TFAM-BDNP showed good adsorption performance for ReO4- in the presence of competing anions and under a wide pH value range, indicating its potential for efficient capture of TcO4-/ReO4- in complex environmental systems.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Xiang-Lan Mao, Qiu-Xia Luo, Yuan-Jun Cai, Xin Liu, Qiao-Qiao Jiang, Cheng-Rong Zhang, Ru-Ping Liang, Jian-Ding Qiu
Summary: The isomerism of a covalent organic framework (COF) greatly affects its electrochemiluminescence (ECL) performance. In this study, two isomeric COFs, TFPB-BD(OMe)(2)-H and TAPB-BD(OMe)(2)-H, were synthesized based on different imine linkages and conversion to the quinoline structure. Despite having the same composition and similar structures, the two COFs exhibited significant differences in photoelectrochemical and ECL fields. TFPB-BD(OMe)(2)-H showed a superior ECL emission compared to TAPB-BD(OMe)(2)-H due to stronger polar interaction and enhanced electron interactions.
ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Environmental
Xin Liu, Rui-Xiang Bi, Zhi-Hai Peng, Lan Lei, Cheng-Rong Zhang, Qiu-Xia Luo, Ru-Ping Liang, Jian-Ding Qiu
Summary: Plasmonic photocatalysis using Bi/Bi2O3_x@COFs as the catalyst effectively removes radioactive uranium from rare earth tailings wastewater. The presence of oxygen vacancy and Schottky potential well in Bi/Bi2O3_x enhances the light absorption performance and electron density of the COFs layer. The synergy between photogenerated electrons and hot electrons enables Bi/ Bi2O3_x@COFs to have high removal capacity and separation coefficient for U(VI). The introduction of localized surface plasmon resonance and Schottky potential well provides a new approach to improve photocatalytic efficiency.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Shun-Mo Yi, Cheng-Rong Zhang, Xin Liu, Wei Jiang, Ru-Ping Liang, Jian-Ding Qiu
Summary: A methyl-rich cationic polymer network (TBT-TCB) was obtained through molecular engineering and successfully applied for the removal of 99TcO4- in harsh environments. The methyl groups in TBT-TCB greatly enhance its resistance to strong acid/alkali, and also improve its hydrophobicity for better affinity towards 99TcO4-. TBT-TCB exhibits excellent robustness, reusability, adsorption selectivity, and adsorption kinetics for 99TcO4-/ReO4-.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Nanoscience & Nanotechnology
Li Zhang, Chen Sun, Sai-Jin Xiao, Quan-Gen Tan, Gui-Ping Yang, Jia-Qi Fan, Yu-Ting Luo, Ru-Ping Liang, Jian-Ding Qiu
Summary: Sulfur mustard (HD) is a highly toxic substance, and exploring efficient catalysts for its degradation is of great significance. Covalent organic frameworks (COFs) as photocatalysts show great potential in HD decontamination. In this study, a photosensitive COF was constructed and silver nanoparticles were deposited on it through postmodification, resulting in enhanced photocatalytic degradation performance.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Xiao-Rong Chen, Cheng-Rong Zhang, Xin Liu, Ru-Ping Liang, Jian-Ding Qiu
Summary: A novel fluorescent ionic covalent organic framework (BTTA-BDNP) based on a linked carbazole unit was developed for the simultaneous monitoring and capture of TcO4-/ReO4-. BTTA-BDNP demonstrated a rapid fluorescence response with a low detection limit (66.7 nM) for ReO4- (a non-radioactive substitute for TcO4-). Moreover, BTTA-BDNP exhibited excellent selectivity and efficiency in trapping ReO4- in complex environments due to its high charge density and hydrophobic skeleton.
CHEMICAL COMMUNICATIONS
(2023)