Article
Pharmacology & Pharmacy
Claudia Vales-Villamarin, Olaya de Dios, Iris Perez-Nadador, Teresa Gavela-Perez, Leandro Soriano-Guillen, Carmen Garces
Summary: The study found that the Ala12Ala genotype was significantly more common in obese females, with carriers having higher weight and BMI. In males, the Ala12Ala genotype was associated with significantly higher levels of HDL-cholesterol and apoA-I. In females, carriers of Ala12Ala seemed to have higher levels of leptin.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Medicine, General & Internal
Maria Mirabelli, Vera Tocci, Alessandra Donnici, Stefania Giuliano, Paola Sarnelli, Alessandro Salatino, Marta Greco, Luigi Puccio, Eusebio Chiefari, Daniela Patrizia Foti, Antonio Brunetti
Summary: The study aimed to determine the impact of modifiable and non-modifiable risk factors in the development of gestational diabetes mellitus (GDM), with a focus on preconception BMI and age. Understanding these factors could inform prevention and intervention strategies in areas with high prevalence of GDM. Importance rating: 8/10.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Xintong Li, Dongmei Xu, Li Zhang, Ruimin Cao, Yide Hao, Lingling Cui, Tingting Chen, Yingying Guo, Jiaxin Li
Summary: The study found that body composition-related indicators were independently associated with the onset of GDM in pregnant women with both pre-pregnancy BMI < 24 kg/m² and BMI >= 24 kg/m² groups. Factors such as body fat mass, visceral fat level, and waist-hip ratio showed higher correlation with pre-pregnancy BMI. Total body water, protein levels, mineral levels, bone mineral content, soft lean mass, fat-free mass, skeletal muscle mass, and basal metabolic rate were found to be protective factors for GDM after adjusting for some confounders. The waist-hip ratio was found to be up to 4.562 times the risk of GDM development in all pregnant women, and gestational weight gain was the best predictor for GDM.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Nana Wang, Yuying Li, Chuanji Guo
Summary: This study demonstrates that waist-corrected body mass index (wBMI), combining BMI and waist circumference measurements, is superior in predicting obesity and diabetes mellitus (DM). The study found a significant association between wBMI and the incidence of DM, with wBMI being a more reliable predictor compared to waist circumference, BMI, and waist-to-height ratio.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Nandini Nair, Eric Vittinghoff, Mark J. Pletcher, Elizabeth C. Oelsner, Norrina B. Allen, Chiadi E. Ndumele, Nancy A. West, Elsa S. Strotmeyer, Kenneth J. Mukamal, David S. Siscovick, Mary L. Biggs, Blandine Laferrere, Andrew E. Moran, Yiyi Zhang
Summary: The study examined the relationship between overweight and obesity in young adulthood and incident diabetes later in life, finding that elevated BMI and waist circumference during young adulthood were independently associated with later-life incident diabetes. Insulin resistance was identified as a key mediator in this association, with other factors such as high-density lipoproteins and triglycerides playing a smaller role.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Biology
Jalal Taneera, Samir Awadallah, Abdul Khader Mohammed, Hema Unnikannan, Nabil Sulaiman
Summary: The study found significantly lower levels of vitamin A in Emirati T2D patients compared to healthy controls, and these levels were influenced by factors such as age, blood glucose, and obesity.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Review
Oncology
Lauren McVicker, Christopher R. Cardwell, Lauren Edge, W. Glenn McCluggage, Declan Quinn, James Wylie, Una C. McMenamin
Summary: This study, through a systematic review and meta-analysis, found that diabetes is associated with worse cancer-specific and overall survival in endometrial cancer patients.
Review
Endocrinology & Metabolism
Zhila Semnani-Azad, Sonia Blanco Mejia, Philip W. Connelly, Richard P. Bazinet, Ravi Retnakaran, David J. A. Jenkins, Stewart B. Harris, Anthony J. Hanley
Summary: The systematic review examined the relationship between sCD163 and T2DM, insulin resistance, and beta-cell dysfunction. Most studies demonstrated a positive association between sCD163 and insulin resistance, with mixed findings on beta-cell function. Studies also explored the impact of weight-reducing interventions and supplementation on sCD163 levels.
Letter
Medicine, General & Internal
David A. Gorelick
Summary: This comprehensive review of human adipose tissue fails to mention the role of the endocannabinoid system in fat metabolism. The endogenous cannabinoids and their receptors, found in both white and brown fat, have been recognized as key players in adipose tissue metabolism. Rimonabant, an inverse agonist of cannabinoid receptor type 1, has shown promising effects as a therapeutic target for obesity, dyslipidemia, and insulin resistance, although its clinical use was discontinued due to neuropsychiatric side effects.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Endocrinology & Metabolism
William H. H. Dietz
Summary: This study compared the prevalence of pediatric obesity during the COVID-19 lockdown with the annual increases in obesity in NHANES. The changes in prevalence observed in two surveys during the lockdown were 28 to 63 times greater than the annual changes in obesity in NHANES. Increases in obesity were greater in Black and Hispanic youth than in White youth. The COVID-19 lockdown exacerbated the disparities in obesity among this age group.
Article
Endocrinology & Metabolism
Ying Peng, Peihong Xu, Juan Shi, Yifei Zhang, Shujie Wang, Qidong Zheng, Yufan Wang, Tingyu Ke, Li Li, Dong Zhao, Yuancheng Dai, Qijuan Dong, Bangqun Ji, Fengmei Xu, Weiqiong Gu, Weiqing Wang
Summary: This study found that once-daily basal insulin was more commonly prescribed and had similar glycemic control effects but less weight gain compared to twice-daily premixed insulin when used as initial therapy for patients with type 2 diabetes who had failed to achieve glycemic control with non-insulin medications.
JOURNAL OF DIABETES
(2022)
Article
Environmental Sciences
Nobuhiko Nagano, Chizuka Kaneko, Shoko Ohashi, Megumi Seya, Itsuro Takigawa, Ken Masunaga, Ichiro Morioka
Summary: This case report describes a patient born extremely preterm SGA with no presentation of adiposity rebound (AR) or obesity during childhood, but developed non-obese type 2 diabetes with low muscle mass. We suggest carefully observing patients born extremely preterm SGA for the development of type 2 diabetes, even if they did not have AR in early childhood or had not become obese.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Limin Wang, Wen Peng, Zhenping Zhao, Mei Zhang, Zumin Shi, Ziwei Song, Xiao Zhang, Chun Li, Zhengjing Huang, Xiaomin Sun, Linhong Wang, Maigeng Zhou, Jing Wu, Youfa Wang
Summary: Based on national data collected in China from 2013 to 2018, the prevalence of diabetes increased, while awareness, treatment, and control of diabetes did not significantly improve. Risk factors such as low physical activity and high intake of red meat, overweight, and obesity also increased during this period.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Endocrinology & Metabolism
Ryusei Ohno, Hidehiro Kaneko, Kensuke Ueno, Hiroyuki Aoki, Akira Okada, Kentaro Kamiya, Yuta Suzuki, Satoshi Matsuoka, Katsuhito Fujiu, Norifumi Takeda, Taisuke Jo, Junya Ako, Hiroyuki Morita, Koichi Node, Hideo Yasunaga, Issei Komuro
Summary: This retrospective observational cohort study found that the risk of developing diabetes mellitus significantly increased when BMI exceeded approximately 20 to 21 kg/m(2). Participants with an increase in BMI of 5.0% or more had a relative risk of 1.33 for developing diabetes, while those with a decrease in BMI of 5.0% or more had a relative risk of 0.82. Furthermore, individuals classified as normal weight, overweight, and obese reduced their risk of developing diabetes when they reduced their BMI, while underweight individuals had an increased risk.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Shuping Yang, Xiangxiang Shi, Wanlu Liu, Zhaokai Wang, Ruoshui Li, Xianzhi Xu, Chaofan Wang, Lei Li, Ruili Wang, Tongda Xu
Summary: This study found a significant association between high TyG-BMI and the risk of heart failure in individuals with diabetes mellitus or prediabetes mellitus.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Integrative & Complementary Medicine
Milad Daneshi-Maskooni, Seyed Ali Keshavarz, Mostafa Qorbani, Siavash Mansouri, Seyed Moayed Alavian, Mahtab Badri-Fariman, Seyed Ali Jazayeri-Tehrani, Gity Sotoudeh
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2019)
Review
Nutrition & Dietetics
Maryam Asadi, Mehran Rahimlou, Farideh Shishehbor, Anahita Mansoori
CLINICAL NUTRITION
(2020)
Article
Medicine, General & Internal
Karolin Abashzadeh, M. Abshirini, F. Siassi, M. Qorbani, F. Koohdani, N. Farasati, G. Sotoudeh
BMJ MILITARY HEALTH
(2020)
Article
Medicine, General & Internal
Reihane Khorasaniha, F. Siassi, F. Khajehnasiri, M. Qorbani, G. Sotoudeh
BMJ MILITARY HEALTH
(2020)
Article
Pharmacology & Pharmacy
Shahin Akhondzadeh, Seyed-Ali Mostafavi, Seyed Ali Keshavarz, Mohammad Reza Mohammadi, Saeed Hosseini, Mohammad Reza Eshraghian
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
(2020)
Article
Chemistry, Medicinal
Sara Asadi, Mohammad Saeed Gholami, Fereydoun Siassi, Mostafa Qorbani, Gity Sotoudeh
PHYTOTHERAPY RESEARCH
(2020)
Article
Medicine, General & Internal
Sufyan Bakuri Suara, Fereydoun Siassi, Mahama Saaka, Abbas Rahimi Foroshani, Gity Sotoudeh
Review
Chemistry, Medicinal
Elmira Karimi, Sama Bitarafan, Seyed Mohammad Mousavi, Nikan Zargarzadeh, Pari Mokhtari, Jessie Hawkins, Alipasha Meysamie, Fariba Koohdani
Summary: Oral vitamin D supplementation does not significantly affect serum FGF23 concentrations in patients with chronic kidney disease, and further high-quality trials are needed to confirm the findings.
PHYTOTHERAPY RESEARCH
(2021)
Article
Nutrition & Dietetics
Zahra Kalantar, Gity Sotoudeh, Zahra Esmaeily, Masoumeh Rafiee, Fariba Koohdani
Summary: The study found significant interactions between CETP Taq1B gene polymorphism and dietary indices on various metabolic biomarkers, such as LDL/HDL, total antioxidant capacity, pentraxin 3, waist circumference, and interleukin-18. These results suggest the combined effects of genetic and dietary factors on metabolic health in T2DM patients.
JOURNAL OF HUMAN NUTRITION AND DIETETICS
(2022)
Article
Endocrinology & Metabolism
Haniyeh Jebraeili, Sakineh Shabbidar, Zahra Sajjadpour, Saeideh Delshad Aghdam, Mostafa Qorbani, Asadollah Rajab, Gity Sotoudeh
Summary: The study showed an inverse association between carbohydrate quality index (CQI) and glycated hemoglobin A1c (HbA1c) in adults with type 1 diabetes mellitus (T1DM), but no significant association was found with respect to CQI with fasting blood glucose, lipid profile, and blood pressure.
JOURNAL OF DIABETES AND METABOLIC DISORDERS
(2021)
Article
Nutrition & Dietetics
Faezeh Abaj, Masoumeh Rafiee, Fariba Koohdani
Summary: The present study found that the PPAR-gamma Pro12Ala polymorphism can intensify the effect of dietary insulin load and insulin index on cardiovascular disease risk factors. Risk-allele carriers who consumed a diet with high insulin load and insulin index were more likely to be obese and have higher inflammatory markers.
JOURNAL OF HUMAN NUTRITION AND DIETETICS
(2022)
Article
Nutrition & Dietetics
Abbas Yousefinejad, Fereydoon Siassi, Abbas Mirshafiey, Fariba Koohdani, Mohammad-Hassan Javanbakh, Reza Sedaghat, Atena Ramezani, Hamed Mohammadi, Mahnaz Zarei, Mahmoud Djalali
PROGRESS IN NUTRITION
(2019)
Review
Nutrition & Dietetics
Masoumeh Moradi, Ehsan Alvandi, Fariba Koohdani
PROGRESS IN NUTRITION
(2019)