Correction
Astronomy & Astrophysics
Zamri Zainal Abidin, Mhd Fairos Asillam, Jun Yi Koay
Summary: The paper has been amended and the updated version can be accessed through a link at the top of the paper.
Article
Nanoscience & Nanotechnology
Guo Yu, Zakir Ali, Anam Sajjad Khan, Kalim Ullah, Humzah Jamshaid, Alam Zeb, Muhammad Imran, Sadia Sarwar, Han-Gon Choi, Fakhar Ud Din
Summary: The study investigates the suitability of nanostructured lipid carriers (NLCs) loaded with miltefosine (HePC) as an anticancer drug for breast cancer treatment. The results show that HePC-NLCs demonstrate enhanced pharmacokinetic, antitumor, and apoptotic effects, emphasizing their potential as a drug delivery system.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Geography, Physical
Xiang Li, Congcong Wen, Qiming Cao, Yanlei Du, Yi Fang
Summary: The paper proposes a semi-supervised method for airborne LiDAR point cloud classification, which achieves good classification performance with only a small fraction of labeled points by introducing a masked supervision module and three unsupervised supervision modules.
ISPRS JOURNAL OF PHOTOGRAMMETRY AND REMOTE SENSING
(2021)
Article
Geochemistry & Geophysics
G. D. Egbert, P. Alken, A. Maute, H. Zhang
Summary: The research introduces a novel approach to empirical modeling of global DV magnetic fields using frequency domain principal components analysis (PCA) to analyze spatial and temporal patterns of ground-based geomagnetic data and physics-based model outputs. This method establishes a continuous FD model for studying mantle electrical conductivity and Earth's deep water cycle.
GEOPHYSICAL JOURNAL INTERNATIONAL
(2021)
Correction
Optics
Haolin Yang, Yue Chen, Kaili Ding, Fuqiang Jia, Kang Li, Nigel Copner
Summary: A correction to this paper has been published.
APPLIED PHYSICS B-LASERS AND OPTICS
(2021)
Article
Computer Science, Artificial Intelligence
Daming Li, Lianbing Deng, Zhiming Cai
Summary: This study combines machine learning technology with innovative computer vision recognition technology to construct an automatic identification system suitable for current traffic demand, improving the stability of the traffic system.
NEURAL COMPUTING & APPLICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Kelton G. Forson, Benjamin O. Bohman, Coriantumr Z. Wayment, Rachel N. Owens, Caitlyn E. McKnight, Rhen C. Davis, Lillian R. Stillwell, Stacey J. Smith, David J. Michaelis
Summary: This study reports the synthesis of a bimetallic Rh(II) complex that enables highly efficient intramolecular allene hydroamination to form 7- to 10-member rings, with a broad substrate scope, and also demonstrates macrocyclizations forming 11- to 15-member N-heterocycles. Mechanistic studies suggest that the reaction proceeds via reversible allene insertion with a Rh-hydride followed by C-N bond-forming reductive elimination. The reactivity observed with the catalyst is derived from its bimetallic nature compared to monometallic Rh complexes.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Engineering, Multidisciplinary
Mariusz Ksiazek
Summary: The author explores the potential use of polymerized sulfur waste as a biocompatible material in biomaterial production, particularly in surgical applications. Experimental studies have demonstrated that polymerized sulfur waste shows promise as a biocomposite, opening up new possibilities for the industry.
COMPOSITES PART B-ENGINEERING
(2021)
Review
Humanities, Multidisciplinary
Ahmad Fekry Moussa, Ibrahim Suleiman Al Qatawneh, Moustafa Elmetwaly Kandeel
Summary: This study focuses on the procedural necessity of primary investigations in the Arab countries, particularly in Egypt. It analyzes the position of the Arab procedural legislation and judiciary systems regarding procedural necessity and argues against expanding discretionary powers that may lead to abuse of officials and restrict individual rights and freedoms.
HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS
(2022)
Article
Computer Science, Artificial Intelligence
Sudan Jha, Eunmok Yang, Alaa Omran Almagrabi, Ali Kashif Bashir, Gyanendra Prasad Joshi
Summary: This study focuses on crime forecasting using a time series model and machine testing systems, comparing different methods in predicting future crime rates. After training and testing over two million datasets, it was found that using a multivariate time series model can provide more accurate predictions of crime numbers compared to existing techniques.
NEURAL COMPUTING & APPLICATIONS
(2021)
Correction
Clinical Neurology
Thorsten Herr, Thomas Hummel, Marcus Vollmer, Carsten Willert, Birgitt Veit, Julie Gamain, Robert Fleischmann, Bernhard Lehnert, Jan-Uwe Mueller, Andrea Stenner, Martin Kronenbuerger
Summary: A correction has been published for this paper.
JOURNAL OF NEURAL TRANSMISSION
(2021)
Article
Multidisciplinary Sciences
Muhammad Aslam
Summary: A new F-test method for two counts data from the Poisson distribution under classical statistics is proposed in this paper. The test is applicable in situations where the count data is uncertain, in the interval, or indeterminate, and it has been shown to be efficient in application and comparison studies.
SCIENTIFIC REPORTS
(2021)
Article
Biology
Christine E. Sosiak, Marek L. Borowiec, Phillip Barden
Summary: Among the social insects, army ants are unique with their coordinated predation, nomadic lifestyle, and specialized wingless queens. This study reports the discovery of the oldest army ant fossil from the Eocene period, named Dissimulodorylus perseus, and reveals unexpected diversity of now-extinct army ant lineages in the Cenozoic.
Correction
Chemistry, Physical
Diana Chaykina, Ismene Usman, Giorgio Colombi, Herman Schreuders, Beata Tyburska-Pueschel, Ziying Wu, Stephan W. H. Eijt, Lars J. Bannenberg, Gilles A. de Wijs, Bernard Dam
Summary: The energy axes of the RBS and ERD data were initially underestimated, but the correction does not affect the data conclusions and peak assignments.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Geriatrics & Gerontology
Claire Pauley, Verena R. Sommer, Malte Kobelt, Attila Keresztes, Markus Werkle-Bergner, Myriam C. Sander
Summary: One important factor contributing to age-related memory decline is the loss of distinctiveness with which information is represented in brain activity. This can be driven by neural attenuation or neural broadening. In this fMRI study, age differences in neural selectivity during encoding, recognition, and repeated encoding were assessed, with a focus on underlying patterns. The findings suggest that intrinsic differences between memory stages may interact with neural activity to manifest as either neural broadening or attenuation. Despite these differential patterns, neural selectivity remains highly correlated across memory stages, indicating the presence of a common mechanism.
NEUROBIOLOGY OF AGING
(2022)
Article
Biochemistry & Molecular Biology
Naig Gueguen, Olivier Baris, Guy Lenaers, Pascal Reynier, Marco Spinazzi
Summary: This article provides an overview of Coenzyme Q (CoQ) distribution in cells and tissues, secondary CoQ deficiency in neurological diseases, and therapeutic strategies for CoQ supplementation. It also discusses improvements in CoQ absorption, formulations, and imaging techniques.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Otorhinolaryngology
Ghita Amalou, Crystel Bonnet, Zied Riahi, Aymane Bouzidi, Soukaina Elrharchi, Amale Bousfiha, Majida Charif, Mostafa Kandil, Guy Lenaers, Christine Petit, Abdelhamid Barakat
Summary: This study identified a relationship between mutation in the MPZL2 gene and recessive mild to moderate non-syndromic deafness, and first reported the discovery of this mutation in a North African family. Exome sequencing and genotyping results confirmed the pathogenicity of this mutation.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2021)
Review
Ophthalmology
Guy Lenaers, Albert Neutzner, Yannick Le Dantec, Christoph Juschke, Ting Xiao, Sarah Decembrini, Sebastian Swirski, Sinja Kieninger, Cavit Agca, Ungsoo S. Kim, Pascal Reynier, Patrick Yu-Wai-Man, John Neidhardt, Bernd Wissinger
Summary: Dominant optic atrophy is an inherited mitochondrial disease characterized by specific degeneration of retinal ganglion cells, primarily caused by OPA1 mutations. OPA1 is crucial for mitochondrial function, and understanding RGC peculiarities is important for studying DOA pathophysiology.
PROGRESS IN RETINAL AND EYE RESEARCH
(2021)
Article
Genetics & Heredity
Benjamin Billiet, Patrizia Amati-Bonneau, Valerie Desquiret-Dumas, Khadidja Guehlouz, Dan Milea, Philippe Gohier, Guy Lenaers, Delphine Mirebeau-Prunier, Johan T. den Dunnen, Pascal Reynier, Marc Ferre
Summary: A public database for NR2F1 gene was established to refine the clinical description of BBSOAS, suggesting additional signs and features for neurological and motor functions.
Article
Ophthalmology
Geoffrey Urbanski, Sophie Assad, Floris Chabrun, Juan Manuel Chao de la Barca, Odile Blanchet, Gilles Simard, Guy Lenaers, Delphine Prunier-Mirebeau, Philippe Gohier, Christian Lavigne, Pascal Reynier
Summary: This study aimed to identify biomarkers in tears that can differentiate pSS from other causes of dry eye syndrome. A metabolomic signature composed of nine key metabolites showed robust performance in predicting pSS status, highlighting the potential for early diagnosis and therapeutic interventions. Adjustment for confounding factors did not affect the link between the metabolomic signature and pSS status, indicating the specificity of these metabolites for pSS.
Article
Biology
Charlotte Orre, Xavier Dieu, Jordan Guillon, Naig Gueguen, Seyedeh Tayebeh Ahmadpour, Jean-Francois Dumas, Salim Khiati, Pascal Reynier, Guy Lenaers, Olivier Coqueret, Arnaud Chevrollier, Delphine Mirebeau-Prunier, Valerie Desquiret-Dumas
Summary: Breast cancer is a common cancer among women, with chemoresistance being a major issue in patient outcomes. Long non-coding RNA SAMMSON has been found to play a role in metabolic reprogramming and chemoresistance in breast cancer cells, providing a potential therapeutic target for overcoming drug resistance.
Article
Genetics & Heredity
Al Mehdi Krami, Aymane Bouzidi, Majida Charif, Ghita Amalou, Hicham Charoute, Hassan Rouba, Rachida Roky, Guy Lenaers, Abdelhamid Barakat, Halima Nahili
Summary: Intellectual disability is a condition characterized by impaired intellectual and adaptive functioning, affecting approximately 1-3% of the population. Recent research has found that mutations in the HECW2 gene are associated with neurodevelopmental disorders such as hypotonia, seizures, and absent language. HECW2 encodes an enzyme that plays a role in brain development by regulating key factors involved in proliferation, apoptosis, and neuronal differentiation. This study identified a homozygous HECW2 mutation in a Moroccan family, inherited in an autosomal recessive pattern, contrasting with previous findings of de novo mutations in HECW2 patients.
EUROPEAN JOURNAL OF MEDICAL GENETICS
(2022)
Review
Genetics & Heredity
Aymane Bouzidi, Hicham Charoute, Majida Charif, Ghita Amalou, Mostafa Kandil, Abdelhamid Barakat, Guy Lenaers
Summary: Inherited retinal dystrophies (IRD) and optic neuropathies (ION) are major causes of visual impairment worldwide, but there is a lack of accurate epidemiological studies and comprehensive genetic research in North Africa.
ORPHANET JOURNAL OF RARE DISEASES
(2022)
Review
Nutrition & Dietetics
Valentin Lacombe, Guy Lenaers, Geoffrey Urbanski
Summary: Cobalamin and transcobalamins play important roles in cancer development, affecting cellular metabolism and being associated with cancer diagnosis and prognosis.
Article
Biochemistry & Molecular Biology
Ahmad Chehaitly, Anne-Laure Guihot, Coralyne Proux, Linda Grimaud, Jade Aurriere, Benoit Legouriellec, Jordan Rivron, Emilie Vessieres, Clement Tetaud, Antonio Zorzano, Vincent Procaccio, Francoise Joubaud, Pascal Reynier, Guy Lenaers, Laurent Loufrani, Daniel Henrion
Summary: The reduction in mitochondrial fusion in mouse endothelial cells was found to impair the dilator response to shear stress, leading to excessive superoxide production and promoting greater atherosclerosis development.
Review
Biochemistry & Molecular Biology
Florian Beignon, Naig Gueguen, Helene Tricoire-Leignel, Cesar Mattei, Guy Lenaers
Summary: Understanding temperature production and regulation in endotherm organisms is a crucial challenge. Mitochondria can act as cellular radiators, controlling heat production and cell temperature. Considering these new thermic paradigms, we discuss conventional wisdom linking mitochondrial functions to cellular thermogenesis.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Jean-Baptiste Domergue, Cinzia Bocca, Rosine De Paepe, Guy Lenaers, Anis M. Limami, Guillaume Tcherkez
Summary: Disruption of mitochondrial complex I (CI) has been found to cause multiple changes in cellular lipids, including leaf, pollen, and seed lipids. This suggests that mitochondrial homeostasis plays a crucial role in regulating the whole cellular lipidome through specific signaling pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Endocrinology & Metabolism
Rahma Felhi, Lamia Sfaihi, Majida Charif, Fakher Frikha, Nissaf Aoiadni, Thouraya Kamoun, Guy Lenaers, Faiza Fakhfakh
Summary: Leigh syndrome (LS) and Leigh-like spectrum are common mitochondrial disorders in infants, caused by pathogenic variants in SLC carriers. A homozygous c.1264 A > G (p.T422A) variant in SLC19A3 was identified in a patient with LS from a consanguineous Tunisian family. This variant affects vitamin-B1 transport, induces mtDNA depletion, and reduces the expression of oxidative stress enzymes, contributing to the LS phenotype.
METABOLIC BRAIN DISEASE
(2023)
Article
Biochemistry & Molecular Biology
Samuel Frey, Guillaume Geffroy, Valerie Desquiret-Dumas, Naig Gueguen, Celine Bris, Sophie Belal, Patrizia Amati-Bonneau, Arnaud Chevrollier, Magalie Barth, Daniel Henrion, Guy Lenaers, Dominique Bonneau, Pascal Reynier, Vincent Procaccio
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2017)
Review
Biochemistry & Molecular Biology
Julien Cassereau, Marc Ferre, Arnaud Chevrollier, Philippe Codron, Christophe Verny, Chadi Homedan, Guy Lenaers, Vincent Procaccio, Pascale May-Panloup, Pascal Reynier
CURRENT MEDICINAL CHEMISTRY
(2017)