Protein Kinase C δ: a Gatekeeper of Immune Homeostasis

T cell PKCδ kinase inactivation induces lupus-like autoimmunity in mice

(2015) Gabriela Gorelik et al.   CLINICAL IMMUNOLOGY

Potentially Beneficial Effect of Hydroxychloroquine in a Patient with a Novel Mutation in Protein Kinase Cδ Deficiency

(2015) Ayca Kiykim et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Autoimmunity and Immunodeficiency

(2015) A. Dosanjh   PEDIATRICS IN REVIEW

Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

(2015) B. Lo et al.   SCIENCE

Novel approaches to the development of targeted therapeutic agents for systemic lupus erythematosus

(2014) Zev Sthoeger et al.   JOURNAL OF AUTOIMMUNITY

Systemic lupus erythematosus

(2014) Larissa Lisnevskaia et al.   LANCET

Protein Kinase C  Promotes Transitional B Cell-Negative Selection and Limits Proximal B Cell Receptor Signaling To Enforce Tolerance

(2014) A. Limnander et al.   MOLECULAR AND CELLULAR BIOLOGY

Correction: Serum Neutralizing Activities from a Beijing Homosexual Male Cohort Infected with Different Subtypes of HIV-1 in China

(2014) Mingshun Zhang et al.   PLoS One

Protein Kinase Cδ Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell-Defective Apoptosis and Hyperproliferation

(2013) Alexandre Belot et al.   ARTHRITIS AND RHEUMATISM

B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C  

(2013) E. Salzer et al.   BLOOD

Loss-of-function of the protein kinase C   (PKC ) causes a B-cell lymphoproliferative syndrome in humans

(2013) H. S. Kuehn et al.   BLOOD

A novel Lyn-protein kinase Cδ/ε-protein kinase D axis is activated in B cells by signalosome-independent alternate pathway BCR signaling

(2013) Benchang Guo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Advances in hematopoietic stem cell transplantation for primary immunodeficiency

(2013) Mary A Slatter et al.   Expert Review of Clinical Immunology

Gene therapy for PIDs: Progress, pitfalls and prospects

(2013) Sayandip Mukherjee et al.   GENE

Inhibition of human B-cell development into plasmablasts by histone deacetylase inhibitor valproic acid

(2013) Anne-Kathrin Kienzler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Primary Immune Deficiency Treatment Consortium (PIDTC) report

(2013) Linda M. Griffith et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunopathogenic mechanisms of systemic autoimmune disease

(2013) Marie Wahren-Herlenius et al.   LANCET

A Hypermorphic Missense Mutation in PLCG2 , Encoding Phospholipase Cγ2, Causes a Dominantly Inherited Autoinflammatory Disease with Immunodeficiency

(2012) Qing Zhou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Protein kinase Cδ oxidation contributes to ERK inactivation in lupus T cells

(2012) Gabriela J. Gorelik et al.   ARTHRITIS AND RHEUMATISM

PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH2-terminal kinase activation

(2012) Noriko Yanase et al.   BMC CELL BIOLOGY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency

(2012) Abdullah Alangari et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Isozyme-specific Interaction of Protein Kinase Cδ with Mitochondria Dissected Using Live Cell Fluorescence Imaging

(2012) Alyssa X. Wu-Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cold Urticaria, Immunodeficiency, and Autoimmunity Related toPLCG2Deletions

(2012) Michael J. Ombrello et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apoptotic Phosphorylation of Histone H3 on Ser-10 by Protein Kinase Cδ

(2012) Choon-Ho Park et al.   PLoS One

PKC-delta and PKC-epsilon: Foes of the same family or strangers?

(2011) Nicolas Duquesnes et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Two Faces of Protein Kinase Cδ: The Contrasting Roles of PKCδ in Cell Survival and Cell Death

(2011) Alakananda Basu et al.   TheScientificWorldJOURNAL

Drug-induced lupus: An update

(2010) Uriel Katz et al.   AUTOIMMUNITY REVIEWS

Update on the hyper immunoglobulin M syndromes

(2010) E. Graham Davies et al.   BRITISH JOURNAL OF HAEMATOLOGY

B Cell Receptor-Mediated Calcium Signaling Is Impaired in B Lymphocytes of Type Ia Patients with Common Variable Immunodeficiency

(2010) C. Foerster et al.   JOURNAL OF IMMUNOLOGY

PKC and the control of localized signal dynamics

(2010) Carine Rosse et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of Phospholipase Cγ Enzymes with Gain-of-Function Mutations

(2009) Katy L. Everett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Receptor crosstalk: reprogramming B cell receptor signalling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontin

(2009) T. L. Rothstein et al.   JOURNAL OF INTERNAL MEDICINE

The Euro-lupus project: epidemiology of systemic lupus erythematosus in Europe

(2009) R Cervera et al.   LUPUS

Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation

(2008) Peter R Wilker et al.   NATURE IMMUNOLOGY

Sequential activation of protein kinase C δ and JNK is required for interferon-α-induced expression of IFIT4

(2007) Xiangyang Huang et al.   CELLULAR SIGNALLING