Article
Multidisciplinary Sciences
Young-Ah Choi, Jung Soo Lee, Yeo Hyung Kim
Summary: We investigated the association between physical activity level and dynapenia in older adults with COPD and found that higher physical activity levels were associated with lower odds of dynapenia. This association was observed only in male patients and individuals with normal weight.
SCIENTIFIC REPORTS
(2022)
Review
Geriatrics & Gerontology
Charles Phillipe de Lucena Alves, Samuel Brito de Almeida, Danielle Pessoa Lima, Pedro Braga Neto, Ana Lucia Miranda, Todd Manini, Lara Vlietstra, Debra L. Waters, Renata Moraes Bielemann, Rosaly Correa-de-Araujo, Ana Paula Fayh, Eduardo Caldas Costa
Summary: This scoping review aimed to map out definitions and assessment methods of muscle quality in older adults. A total of 96 articles were included, revealing a substantial heterogeneity of definitions and assessment methods across functional and morphological domains. Standardizing the definition of muscle quality may help utilize it as a potential marker of skeletal muscle health in older adults.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Nutrition & Dietetics
Hyeonmok Kim, Sun Hee Beom, Tae Ho Kim, Beom-Jun Kim
Summary: This study explored the relationship between water intake and hand grip strength in older adults, finding that the correlation between water intake and hand grip strength may not be significant, potentially influenced by other factors such as age, body size, and resistance exercise.
Article
Medicine, General & Internal
Thiti Wongtangman, Phraewa Thatphet, Hamid Shokoohi, Kathleen McFadden, Irene Ma, Ahad Al Saud, Rachel Vivian, Ryan Hines, Jamie Gullikson, Christina Morone, Jason Parente, Stany Perkisas, Shan W. Liu
Summary: This study aimed to determine the association between point-of-care-ultrasonography (POCUS)-measured sarcopenia and grip strength, as well as the history of prior-year falls among older adults admitted to the emergency department observation unit (EDOU). The study found that POCUS-measured thigh muscle thickness and normal grip strength were positively correlated with a history of prior-year falls. Therefore, measuring thigh muscle thickness can identify high-risk individuals for falls.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biology
Eun-Hee Jang, Ye-Ji Han, Seong-Eun Jang, Seungmin Lee
Summary: This systematic review found that various diet qualities are significantly associated with a decreased risk of sarcopenia, especially the Mediterranean diet and Nordic diet. However, the results from non-European countries were inconsistent.
Article
Nutrition & Dietetics
Corey Linton, Hattie H. Wright, Daniel P. Wadsworth, Mia A. Schaumberg
Summary: The research reveals that low-grade systemic inflammation and diets with pro-inflammatory properties contribute to muscle degeneration in older adults, leading to loss of muscle mass, strength, and function.
Article
Geriatrics & Gerontology
Je Hyun Seo, Young Lee
Summary: This study found that moderate to vigorous physical activity (PA) is associated with higher skeletal muscle mass and muscle strength in older adults. Specifically, engaging in high-intensity PA is positively correlated with the prevention of sarcopenia.
Article
Geriatrics & Gerontology
R. S. Feitosa, A. C. B. Marini, G. D. Pimentel
Summary: This study examined the prevalence of sarcopenia in elderly hemodialysis patients and found an association between fat mass percentage and SARC-F/SARC-F+CC. A significant proportion (37.5%) of patients were at risk of muscle function loss, and adiposity was linked to an increased likelihood of sarcopenia by 25%.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Nutrition & Dietetics
Mirta Crovetto Mattassi, Camila Henriquez Mella, Lissette Perez Bocaz
Summary: This study investigated sarcopenia and nutritional status in Chilean older adults aged 65 and older. The results showed that nearly 50% of the participants had probable sarcopenia, with obese individuals having a higher risk. There is an association between nutritional status and sarcopenia.
Article
Geriatrics & Gerontology
Satoshi Seino, Akihiko Kitamura, Takumi Abe, Yu Taniguchi, Hiroshi Murayama, Hidenori Amano, Mariko Nishi, Yu Nofuji, Yuri Yokoyama, Miki Narita, Shoji Shinkai, Yoshinori Fujiwara
Summary: Disability risk is more dependent on muscle strength and physical performance in older adults, while mortality risk is more influenced by muscle mass in men and lower fat mass along with muscle strength and physical performance in women.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Multidisciplinary Sciences
Misa Nakamura, Masakazu Imaoka, Hidetoshi Nakao, Mitsumasa Hida, Fumie Tazaki, Ryota Imai, Hirotoshi Utsunomiya, Hiroshi Hashizume
Summary: The need for support and care is a major global issue, with locomotive syndrome (LS) being a condition where healthcare services are needed due to mobility issues. This study found a strong relationship between oral dysfunction and LS, with elderly individuals experiencing a decline in masticatory function and difficulty swallowing having higher odds of LS. The findings suggest that addressing oral dysfunction may contribute to preventing LS.
SCIENTIFIC REPORTS
(2021)
Review
Multidisciplinary Sciences
Safiyyah Nurnajah Wan, Chiann Ni Thiam, Qi Xuan Ang, Julia Engkasan, Terence Ong
Summary: This study examines the new incidences of hospital sarcopenia, associated risk factors, and health outcomes in older people. The prevalence of sarcopenia ranged from 14.1% to 55% depending on diagnostic criteria and cut-off points used. Between 12% to 38.7% of patients developed new sarcopenia following hospitalization. Risk factors included older age, longer duration of bed rest, lower baseline body mass index, cognitive impairment, and activities of daily living disability. No studies reported health outcomes associated with newly developed sarcopenia in hospital.
Article
Health Care Sciences & Services
Helio Jose Coelho-Junior, Riccardo Calvani, Anna Picca, Matteo Tosato, Francesco Landi, Emanuele Marzetti
Summary: The study aimed to examine the relationship between adherence to specific exercise modalities and the severity of sarcopenia in older adults in Italy. The data was collected as part of the Longevity Check-Up 7+ (Lookup 7+) project. The results showed that engagement in running and/or swimming and strength training with or without stretching had a positive impact on reducing the severity of sarcopenia in older adults.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Geriatrics & Gerontology
Deniz Mut Surmeli, Hulusi Can Karpuzcu, Volkan Atmis, Caglar Cosarderelioglu, Ahmet Yalcin, Murat Varli, Sevgi Aras
Summary: This study investigated the association between sarcopenia and erectile dysfunction (ED) in older men. The results showed that sarcopenia was associated with an increased risk of moderate-severe ED, and decreased muscle strength and muscle mass were also associated with an increased risk of moderate-severe ED.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2022)
Article
Geriatrics & Gerontology
Dong Kee Jang, Hyoun Woo Kang, Yeo Hyung Kim
Summary: This study examines the independent association between anemia and dynapenia in older adults. The results suggest a significant relationship between anemia and dynapenia, particularly in men.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Geriatrics & Gerontology
Joshua Barzilay, Petra Buzkova, Michael G. Shlipak, Mary F. Lyles, Nisha Bansal, Pranav S. Garimella, Joachim H. Ix, Jorge R. Kizer, Elsa S. Strotmeyer, Luc Djousse, Mary L. Biggs, David Siscovick, Kenneth J. Mukamal
Summary: The study showed that spot urine creatinine concentration is positively associated with muscle mass and health outcomes in older adults.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Geriatrics & Gerontology
Jenna M. Napoleone, Robert M. Boudreau, Brittney S. Lange-Maia, Samar R. El Khoudary, Kelly R. Ylitalo, Andrea M. Kriska, Carrie A. Karvonen-Gutierrez, Elsa S. Strotmeyer
Summary: This study found that midlife metabolic syndrome groups were associated with poor physical performance in early old age multiethnic women, suggesting that managing midlife metabolic function may improve physical performance later in life.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Endocrinology & Metabolism
Muriel E. Babey, Susan K. Ewing, Elsa S. Strotmeyer, Nicola Napoli, Anne L. Schafer, Eric Vittinghoff, Caren M. Gundberg, Ann Schwartz
Summary: Mouse models suggest that undercarboxylated osteocalcin (ucOC), produced by the skeleton, protects against type 2 diabetes development, whereas human studies have been inconclusive. This study aimed to investigate the association between ucOC or total OC and incident type 2 diabetes or changes in glucose metabolism in older adults. The results showed no significant association between baseline undercarboxylated or total osteocalcin and the risk of incident type 2 diabetes or changes in glucose metabolism in older adults.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Geriatrics & Gerontology
Rebekah Harris, Elsa S. Strotmeyer, Leena Sharma, C. Kent Kwoh, Jennifer S. Brach, Robert Boudreau, Jane A. Cauley
Summary: This study examined how the severity of radiographic knee osteoarthritis (KOA) affects recurrent falls in middle-aged and older individuals. The results showed that older adults with radiographic evidence of KOA had a higher likelihood of experiencing recurrent falls compared to those without KOA, regardless of established risk factors. On the other hand, middle-aged adults with KOA did not have an increased odds of recurrent falls, except for those with possible KOA.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Lingshu Xue, Robert M. Boudreau, Julie M. Donohue, Janice C. Zgibor, Zachary A. Marcum, Tina Costacou, Anne B. Newman, Teresa M. Waters, Elsa S. Strotmeyer
Summary: This study examined the association between persistent polypharmacy and treated fall injuries in community-dwelling older adults, concluding that persistent polypharmacy, especially in combination with medications that increase fall risk, was linked to an increased risk of fall injuries in both inpatient and outpatient settings.
Article
Medicine, General & Internal
Daniel H. Solomon, Alicia Colvin, Brittney S. Lange-Maia, Carol Derby, Sheila Dugan, Elizabeth A. Jackson, Kristine Ruppert, Carrie Karvonen-Gutierrez, Leah Santacroce, Elsa S. Strotmeyer, Nancy E. Avis
Summary: This study examines the factors associated with declines in physical health and function among women in midlife. The results show that declines in women's physical health and function between ages 55 and 65 years are relatively common. Factors such as baseline physical health, BMI, educational attainment, smoking, osteoarthritis, depressive symptoms, and cardiovascular disease are associated with clinically important declines in physical health.
Article
Clinical Neurology
Willa D. Brenowitz, Nathaniel M. Robbins, Elsa S. Strotmeyer, Kristine Yaffe
Summary: The study found that lower extremity peripheral nerve impairments, especially sensory impairments, were associated with a higher risk of dementia. These associations may indicate a shared susceptibility to nervous system degeneration.
Article
Endocrinology & Metabolism
R. J. Harris, N. Parimi, P. M. Cawthon, E. S. Strotmeyer, R. M. Boudreau, J. S. Brach, C. K. Kwoh, J. A. Cauley
Summary: This study aimed to evaluate the associations between the components of sarcopenia and fracture types. The findings showed that men with slow walking speed had a higher risk of experiencing any clinical, hip, or major osteoporotic fracture compared to those with normal walking speed. However, low lean mass and low grip strength were not significantly associated with fractures.
OSTEOPOROSIS INTERNATIONAL
(2022)
Article
Geriatrics & Gerontology
Mary E. Winger, Paolo Caserotti, Jane A. Cauley, Robert M. Boudreau, Sara R. Piva, Peggy M. Cawthon, Eric S. Orwoll, Kristine E. Ensrud, Deborah M. Kado, Elsa S. Strotmeyer
Summary: This study investigated the application of lower-extremity power and upper-extremity strength in fall injuries and found that lower leg power and grip strength predicted future fall injury risk in older men, independent of physical performance.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Gerontology
Brittney S. Lange-Maia, Samar R. El Khoudary, Carolyn J. Crandall, Yanyu Zhang, Carrie A. Karvonen-Gutierrez, Kelley Pettee Gabriel, Bradley M. Appelhans, Elsa S. Strotmeyer, Kelly R. Ylitalo, Kelly Karavolos, Howard M. Kravitz, Sheila A. Dugan, Imke Janssen
Summary: The study found that physical function before menopause is associated with cardiovascular disease risk, with women who have substantial limitations having a higher risk compared to those with no limitations.
JOURNAL OF AGING AND HEALTH
(2023)
Article
Geriatrics & Gerontology
Sharon C. Welburn, Erin E. Fanning, Jane A. Cauley, Patrick J. Brown, Elsa S. Strotmeyer, Robert M. Boudreau, Todd M. Bear, Kyle D. Moored, Peggy M. Cawthon, Katie L. Stone, Nancy W. Glynn
Summary: This study found that both physical and mental fatigability are associated with increased fall risk in elderly men, with physical fatigability increasing the risk by 20% and mental fatigability increasing the risk of recurrent falling by 35% and 44% respectively.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Steven R. Cummings, Anne B. Newman, Paul M. Coen, Russell T. Hepple, Robin Collins, Kimberly Kennedy, Michelle Danielson, Kathy Peters, Terri Blackwell, Eileen Johnson, Theresa Mau, Eric G. Shankland, Li-Yung Lui, Sheena Patel, Dani Young, Nancy W. Glynn, Elsa S. Strotmeyer, Karyn A. Esser, David J. Marcinek, Bret H. Goodpaster, Stephen Kritchevsky, Peggy M. Cawthon
Summary: The SOMMA study aims to understand the biological basis of aging and mobility decline by collecting data, tissues, and images. The multidisciplinary team includes clinical centers, a biorepository, and a coordinating center. Participants are followed with regular exams and various assessments. The study will lay the foundation for discoveries in the biology of human aging and mobility.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Rheumatology
Karen Y. Cheng, Elsa S. Strotmeyer, Deborah M. Kado, John T. Schousboe, Simon Schenk, Michael Nevitt, Nancy E. Lane, Jan M. Hughes-Austin
Summary: Metabolic syndrome (MetS) was associated with hip osteoarthritis (OA) in women, while obesity was associated with hip OA in men. These findings suggest different mechanisms of hip OA development in men and women.
ACR OPEN RHEUMATOLOGY
(2023)
Article
Endocrinology & Metabolism
Jenna M. Napoleone, Rachel G. Miller, Susan M. Devaraj, Bonny Rockette-Wagner, Vincent C. Arena, Elizabeth M. Venditti, Kaye Kramer, Elsa S. Strotmeyer, Andrea M. Kriska
Summary: Attending maintenance sessions and meeting the 6-month WL goal increased the odds of achieving the 12-month 5% WL goal. However, for those who did not meet the 6-month WL goal, attending maintenance sessions did not improve the odds of 12-month WL success. Medicare-eligible adults aged 65 and older were more likely to achieve the 12-month WL goal.
SCIENCE OF DIABETES SELF-MANAGEMENT AND CARE
(2021)
Article
Geriatrics & Gerontology
Rafaela Soares Rech, Elsa S. Strotmeyer, Brittney S. Lange-Maia, Fernando Neves Hugo, Barbara Niegia Garcia de Goulart, Juliana Balbinot Hilgert, Eleanor M. Simonsick
Summary: In older adults, slow motor nerve conduction velocity and impairments in sensorimotor peripheral nerve function are associated with a higher likelihood of swallowing difficulties, while other nerve impairments are not related to swallowing impairment.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)