Review
Medicine, General & Internal
Yasutsugu Akasaki, Takenori Inomata, Jaemyoung Sung, Masahiro Nakamura, Koji Kitazawa, Kendrick Co Shih, Takeya Adachi, Yuichi Okumura, Kenta Fujio, Ken Nagino, Akie Midorikawa-Inomata, Mizu Kuwahara, Kunihiko Hirosawa, Tianxiang Huang, Yuki Morooka, Hurramhon Shokirova, Atsuko Eguchi, Akira Murakami
Summary: This systematic review aimed to determine the comorbid dry eye (DE) and allergic conjunctivitis (AC) prevalence. The results showed that the incidence of AC among individuals with DE ranged from 6.2% to 38.0%, while the incidence of DE among individuals with AC ranged from 0.9% to 97.5%. Furthermore, the meta-analysis revealed that approximately 47.2% of patients with AC had comorbid DE, and approximately 17.8% of patients with DE had comorbid AC. Therefore, complementary screening and treatment for patients with DE and AC may play a significant role in preventing chronic ocular damage and improving long-term outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Emmanuel Kobia-Acquah, Prince Kwaku Akowuah, Ellen Konadu Antwi-Adjei, Philip Mensah Forkuo, Nana Yaa Koomson, Samuel Odoi Odotei, Emmanuel Alabi, Richard Donkor
Summary: In Ghana, the prevalence of contact lens complications is relatively high, with soft contact lens wearers being more susceptible. The most common complication reported is giant papillary conjunctivitis. Inappropriate lens cleaning and poor personal hygiene are the main causes of complications.
CONTACT LENS & ANTERIOR EYE
(2021)
Review
Behavioral Sciences
Jiehong Huang, Ruoyu Li, Lixi Li, Yunping Song, Lingjing Jin
Summary: This systematic review explores the association between tic disorders (TD) and allergic diseases (AD) through literature compilation and evidence analysis. It identifies a positive correlation between TD and asthma, allergic rhinitis, and allergic conjunctivitis. Provisional tic disorder (PTD) patients are more likely to suffer from these three AD. Shared genetic and etiological factors are suggested as responsible for this AD-TD association.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Review
Ophthalmology
Ishith Seth, Gabriella Bulloch, Michael Vine, Joseph Outmezguine, Nimish Seth, James Every, Mark Daniell
Summary: This study investigated the association between keratoconus (KC) and allergic eye diseases, eye rubbing, and atopy. The results showed a significant association between KC and eye rubbing, family history, and allergies, but not with allergic eye disease, atopy, asthma, and allergic rhinitis.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Review
Chemistry, Physical
Tina Lovrec-Krstic, Kristjan Orthaber, Uros Maver, Tomislav Sarenac
Summary: The field of ophthalmology is rapidly expanding with the increasing incidence of eye-related diseases. Due to an aging population and climate change, the number of ophthalmic patients will continue to rise, leading to potential under-treatment. Drug-loaded contact lenses provide a promising alternative to eye drops for ocular therapy, potentially transforming clinical practice. This review focuses on current roles, materials, drug binding, and future developments of contact lenses in ocular drug delivery.
Article
Ophthalmology
Hayato Tanaka, Yoko Tatsukawa, Kayo Yoshitomi, Hitoshi Tabuchi, Atsuki Fukushima
Summary: Half of the CL users with ocular-allergic symptoms preferred not to switch to spectacles. Continued CL use can improve productivity and quality of life. This study described the clinical courses of CL users with ocular-allergic conjunctivitis who started ARCL trials on their eyes.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Review
Pharmacology & Pharmacy
Hongyu Yang, Ming Zhao, Dandan Xing, Jian Zhang, Ting Fang, Faxing Zhang, Zhihao Nie, Yaming Liu, Lihua Yang, Ji Li, Dongkai Wang
Summary: The number of people with eye diseases has increased due to the use of electronics. However, the bioavailability of eye drops remains low. Therefore, the development of contact lenses that can deliver drugs for extended periods without affecting vision has become a focus of research. This article reviews the physical and chemical properties of drug-laden contact lenses, the development and classification of contact lenses, and the characteristics of commonly used materials. It also discusses methods to overcome the problems of high burst and short release duration using drug-laden contact lenses, and predicts the future direction of contact lens research.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2023)
Article
Veterinary Sciences
Irene Cerrada, Marta Leiva, Rita Vilao, Teresa Pena, Jose Rios
Summary: This study evaluated the incidence, clinical features, treatment, and outcome of canine follicular conjunctivitis (CFC). The results showed that CFC is a bilateral ocular disease occurring at any age, but the clinical presentation is influenced by age. In adult dogs, CFC is less severe, less commonly affects the nictitating membrane, and responds more quickly to topical treatment.
VETERINARY OPHTHALMOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Yangzhi Zhu, Rohollah Nasiri, Elham Davoodi, Shiming Zhang, Sourav Saha, Matthew Linn, Lu Jiang, Reihaneh Haghniaz, Martin C. Hartel, Vadim Jucaud, Mehmet R. Dokmeci, Anna Herland, Ehsan Toyserkani, Ali Khademhosseini
Summary: The study investigates the use of contact lenses with microchannels to enhance tear flow from the pre-lens tear film to the post-lens ocular surface. The results demonstrate that the tear transport can be enhanced by an artificial eyelid motion in a pressure range similar to human eyelid pressure. This research shows the feasibility of developing microfluidic contact lenses to prevent or minimize contact lens-induced dry eye and discomfort.
Article
Veterinary Sciences
Esmeralda Delgado, Erica Gomes, Solange Gil, Ana Mafalda Lourenco
Summary: This study contributes to the characterization and clinical staging of canine allergic conjunctivitis (cAC). Severity of cAC is not correlated to gender or age, and common symptoms include conjunctival hyperemia, chemosis, and ocular pruritus.
BMC VETERINARY RESEARCH
(2023)
Article
Medicine, General & Internal
Minjie Chen, Anji Wei, Bilian Ke, Jun Zou, Lan Gong, Yan Wang, Chaoran Zhang, Jianjiang Xu, Jia Yin, Jiaxu Hong
Summary: The study compared the efficacy of 0.05% azelastine and 0.1% tacrolimus eye drops in combination with 0.1% tacrolimus monotherapy in pediatric patients with VKC. It was found that the combination therapy led to faster and greater improvements in clinical signs and symptoms of VKC in children, with no severe adverse effects reported in either group.
FRONTIERS IN MEDICINE
(2021)
Review
Medicine, General & Internal
Junji Ono, Hiroshi Toshida
Summary: The use of drug-eluting daily disposable soft contact lenses containing anti-allergic medication can alleviate ocular allergic symptoms and allow patients to continue wearing contact lenses.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Review
Ophthalmology
Richard M. Pearson
Summary: The aim of this review is to commemorate the 75th anniversary of the introduction of the original corneal contact lens of Tuohy in 1948. By consulting American documents in the public domain, the author provides a comprehensive biography of Kevin M Tuohy, inventor of the corneal contact lens, and addresses historical inaccuracies regarding its design and dimensions. The clinical success of the Tuohy lens and its simpler fitting procedure compared to scleral lenses have had a significant impact on the development of contact lens practice.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Pharmacology & Pharmacy
Jiayong Liu, Xue Wang
Summary: This study successfully developed ofloxacin-loaded niosomes for contact lenses, which can improve drug release capacity and sustain ocular drug delivery. Compared to conventional soaking method contact lenses, the novel OFL-nio-L lenses showed enhanced optophysical properties and sustained drug release.
Article
Medicine, General & Internal
Hang Song, Kang Xiao, Hanyi Min, Zhengyu Chen, Qin Long
Summary: In this study, the differences in conjunctival sac microbiome composition between allergic conjunctivitis (AC) patients and normal controls (NCs) were investigated using high-throughput 16S rDNA sequencing metagenomic analysis. The results showed that there was no significant difference in alpha diversity between the two groups, but the Shannon index was higher in the AC group. Beta diversity analysis revealed divergent microbiome composition in different groups. The top five abundant genera were distinct between the AC and NC groups, and the Bacillus/Acinetobacter ratio was higher in the AC group.
JOURNAL OF CLINICAL MEDICINE
(2022)
