Development of a rapid RP-UHPLC–MS method for analysis of modifications in therapeutic monoclonal antibodies

Title
Development of a rapid RP-UHPLC–MS method for analysis of modifications in therapeutic monoclonal antibodies
Authors
Keywords
Monoclonal antibodies, MAbs, IdeS, UHPLC, Mass spectrometry, High resolution, Fc oxidation, CQAs, Peptide mapping, Process characterization and process validation (PC/PV) studies
Publisher
Elsevier BV
Online
2016-05-13
DOI
10.1016/j.jchromb.2016.05.017

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