Journal
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
Volume 1020, Issue -, Pages 90-95Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jchromb.2016.03.023
Keywords
Jatropha curcas; Phorbol esters; Jerky pet treats; High resolution; Accurate mass; LC-MS method
Funding
- U.S. Department of Energy
- U.S. Food and Drug Administration
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Since 2007, the U.S. FDA's Center for Veterinary Medicine (CVM) has been investigating reports of pets becoming ill after consuming jerky pet treats. jerky used in pet treats contains glycerin, which can be made from vegetable oil or as a byproduct of biodiesel production. Because some biodiesel is produced using oil from Jatropha curcas, a plant that contains toxic compounds including phorbol esters, CVM developed a liquid chromatography-mass spectrometry (LC-MS) screening method to evaluate investigational jerky samples for the presence of these toxins. Results indicated that the samples analyzed with the new method did not contain Jatropha toxins at or above the lowest concentration tested. Published by Elsevier B.V.
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