Article
Psychology, Clinical
Duc Tin Le, Son Van Huynh, Truong Vuong Vu, Nhu-Thuyen Dang-Thi, Bao-Tran Nguyen-Duong, Kiet Anh Duong, Tan Ngan Mai, Thanh Nhon Huynh, Phuc Tan Mai, Vinh-Long Tran-Chi
Summary: The purpose of this study was to explore the relationship between personality traits and verbal or physical aggression in Vietnamese adolescents. The findings indicated a significant interaction between personality traits, specifically extraversion and neuroticism, and physical aggression, verbal aggression, and anger. Gender and school year also influenced personality traits. Importantly, physical and verbal aggression mediated the relationship between personality traits and aggressive behavior.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2023)
Article
Health Care Sciences & Services
Hilda T. Maibach, Michael J. Brownstein, Steven M. Hersch, Karen E. Anderson, Debra E. Itzkowitz, Eve M. Damiano, Neal G. Simon
Summary: SRX246, an orally available V1a receptor antagonist, was found to reduce aggressive behavior in HD patients and was well tolerated.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Clinical Neurology
Katharina Schiller, Saoussen Berrahmoune, Christelle Dassi, Isabelle Corriveau, Taghreed A. Ayash, Bradley Osterman, Chantal Poulin, Michael Shevell, Elisabeth Simard-Tremblay, Guillaume Sebire, Kenneth A. Myers
Summary: This randomized double-blind placebo-controlled crossover trial showed that memantine is a safe and effective treatment for children with developmental and epileptic encephalopathy, improving both seizure control and cognitive function.
Article
Multidisciplinary Sciences
Caihong Han, Qionglin Peng, Mengshi Sun, Xinyu Jiang, Xiangbin Su, Jiangtao Chen, Mingze Ma, Huan Zhu, Xiaoxiao Ji, Yufeng Pan
Summary: Most animal species exhibit dimorphic sexual behaviors, with males showing higher levels of aggression. Current models have focused on the male-specific product of the fruitless gene, fruM, which controls male courtship and male-specific aggression patterns in fruit flies and describes a male-specific mechanism underlying sexually dimorphic behaviors. This study demonstrates that the doublesex gene (dsx), which produces male-specific DsxM and female-specific DsxF transcription factors, also plays a role in the nervous system to control both male and female sexual and aggressive behaviors.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Psychology, Multidisciplinary
Qian Zhang, El-Lim Kim, JingJin Tian, Yi Cao
Summary: The current research found that practicing copying pleasant calligraphy can effectively reduce aggressive behaviors in children, with a more significant effect on boys. This effect is not moderated by trait aggression, and is fully mediated by aggressive motivation.
CURRENT PSYCHOLOGY
(2021)
Article
Psychology, Multidisciplinary
Qian Zhang
Summary: The study showed that viewing prosocial cartoons can immediately decrease children's aggression, with boys showing less aggression and girls showing more aggression when exposed to prosocial cartoons. The effect of prosocial cartoons on aggression is partially mediated by aggressive motivation, especially for boys.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Clinical Neurology
Francesca A. Cupaioli, Fabio A. Zucca, Cinzia Caporale, Klaus-Peter Lesch, Luca Passamonti, Luigi Zecca
Summary: In modern societies, efforts are being made to improve the quality of life by better understanding the brain's influence on aggression. Neurobiological research shows that changes in specific brain regions are related to aggression, and genetic and environmental factors also play a significant role in aggressiveness.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Article
Multidisciplinary Sciences
Silvana Valtcheva, Habon A. Issa, Chloe J. Bair-Marshall, Kathleen A. Martin, Kanghoon Jung, Yiyao Zhang, Hyung-Bae Kwon, Robert C. Froemke
Summary: This study describes a neural circuit that relays auditory information about infant cries to mouse oxytocin neurons, inducing the release of oxytocin and modulating maternal behavior.
Article
Psychology, Social
David S. Chester, Michael L. Crowe, Courtland S. Hyatt, Joshua D. Miller
Summary: The study aimed to factor analyze a broad range of aggression measures to identify a comprehensive, coherent factor structure. Through this analysis, a six-factor structure was derived, capturing various forms of aggression. The findings mostly supported widely-accepted models of aggressive personality.
JOURNAL OF PERSONALITY
(2023)
Article
Clinical Neurology
Emre Kumral, Fatma Ece Cetin, Hueseyin Nezih Ozdemir, Hande Celikay, Sevinc Ozkan
Summary: This study investigated the relationship between post-stroke aggressive behavior (PSAB) in stroke patients and neuropsychological and neuroimaging findings. 11.1% of patients with first ischemic stroke exhibited aggressive behavior, which was associated with older age, higher rates of depression and anxiety, and lesions in the lower parietal lobe and lateral frontal gyrus.
ACTA NEUROLOGICA BELGICA
(2023)
Article
Behavioral Sciences
Isabella L. S. Santos, Carlos Eduardo Pimentel, Tailson E. Mariano, Ericarla Veronica Almeida Dias
Summary: This study aimed to investigate the influence of aggressive online content exposure and personality on aggressive content sharing, with positive and negative affects playing a mediating role.
AGGRESSIVE BEHAVIOR
(2023)
Article
Agriculture, Dairy & Animal Science
Gust Boiten, Robin van Iersel, Rianne Pinxten, Marcel Eens
Summary: Animals use aggression to compete for resources and protect their offspring. This study examined male and female aggression towards opponents of the same and opposite sex in blue tits. The results showed that females were more aggressive, possibly due to competition for nesting sites and larger reproductive investments.
Article
Psychology, Multidisciplinary
Anna Di Norcia, Anna Silvia Bombi, Giuliana Pinto, Chiara Mascaro, Eleonora Cannoni
Summary: This study explores the representation of friendship during middle childhood and its impact on aggressive behavior. It found that the quality of friendship is crucial, with relatedness being the dominant feature. Conflict is not always present when children do not feel fine with their friends, but boys and girls differ in managing relatedness and individuality in problematic situations.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychiatry
Stephanie Klein Tuente, Stefan Bogaerts, Wim Veling
Summary: This study investigated aggressive behavior in forensic psychiatric inpatients and found that most patients exhibited moderate or severe aggressive behavior, with a significant portion displaying physical aggression. Preceding incidents of physical aggression were typically preceded by non-physical aggression, indicating potential early warning signs.
PSYCHIATRY RESEARCH
(2021)
Review
Medicine, General & Internal
Francesco Corallo, Anna Anselmo, Rosanna Palmeri, Marcella Di Cara, Caterina Formica, Simona De Salvo, Antonino Todaro, Carmela Rifici, Silvia Marino, Placido Bramanti, Viviana Lo Buono
Summary: This study conducted a descriptive review on tests used to detect aggressive dimensions following traumatic brain injury, finding various psychometric tools for assessment. Further investigation is needed to clarify the reliability of these tools for early intervention and reduction of violent behavior.
Letter
Nursing
Ian R. McGrane, Shannon Mertens
ARCHIVES OF PSYCHIATRIC NURSING
(2018)
Article
Psychiatry
Ian R. McGrane, Michael D. Shuman
HARVARD REVIEW OF PSYCHIATRY
(2018)
Article
Pediatrics
Laura M. Steinauer, Jonathan G. Leung, Betsy Walters Burkey, Ian R. McGrane, Victoria Letts, Jessica L. Goren, Dawn M. Hoeft, Sandra Mullen, Megan Maroney, Kathryn M. Schak, Jennifer L. Vande Voort
JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
(2018)
Letter
Health Policy & Services
Ian R. McGrane, Ruby K. Gale, Joshua G. Loveland
PSYCHIATRIC SERVICES
(2018)
Letter
Pediatrics
Ian R. McGrane, Corle M. Morefield, Kary L. Aytes
JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
(2019)
Review
Psychiatry
Ian R. McGrane, Faddy A. Omar, Natalie F. Morgan, Michael D. Shuman
Summary: Lithium is a viable pharmacotherapeutic option for patients on dialysis, with close monitoring of serum levels recommended to prevent toxicity. The dosing and timing of lithium administration can vary among individuals, and careful consideration should be given to the pharmacokinetic properties of lithium in dialysis patients.
INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE
(2022)
Editorial Material
Clinical Neurology
Ian R. McGrane, Robert C. Munjal, Shelby L. Skauge, Jason R. Molinaro
Review
Pharmacology & Pharmacy
Jose de Leon, Georgios Schoretsanitis, Robert L. Smith, Espen Molden, Anssi Solismaa, Niko Seppala, Miloslav Kopecek, Patrik Svancer, Ismael Olmos, Carina Ricciardi, Celso Iglesias-Garcia, Ana Iglesias-Alonso, Edoardo Spina, Can-Jun Ruan, Chuan-Yue Wang, Gang Wang, Yi-Lang Tang, Shih-Ku Lin, Hsien-Yuan Lane, Yong Sik Kim, Se Hyun Kim, Anto P. Rajkumar, Dinora F. Gonzalez-Esquivel, Helgi Jung-Cook, Trino Baptista, Christopher Rohde, Jimmi Nielsen, Helene Verdoux, Clelia Quiles, Emilio J. Sanz, Carlos De las Cuevas, Dan Cohen, Peter F. J. Schulte, Aygun Ertugrul, Nitin Chopra, Betsy McCollum, Charles Shelton, Robert O. Cotes, Arun R. Kaithi, John M. Kane, Saeed Farooq, Chee H. Ng, John Bilbily, Christoph Hiemke, Carlos Lopez-Jaramillo, Ian McGrane, Fernando Lana, Chin B. Eap, Manuel Arrojo-Romero, Erich Seifritz, Susanna Every-Palmer, Chad A. Bousman, Emmanuel Bebawi, Rahul Bhattacharya, Deanna L. Kelly, Yuji Otsuka, Judit Lazary, Rafael Torres, Agustin Yecora, Mariano Motuca, Sherry K. W. Chan, Monica Zolezzi, Sami Ouanes, Domenico De Berardis, Sandeep Grover, Ric M. Procyshyn, Richard A. Adebayo, Oleg O. Kirilochev, Andrey Soloviev, Konstantinos N. Fountoulakis, Alina Wilkowska, Muhammad Ayub, Alzira Silva, Raphael M. Bonelli, Jose M. Villagran-Moreno, Benedicto Crespo-Facorro, Henk Temmingh, Eric Decloedt, Maria R. Pedro, Hiroyoshi Takeuchi, Masaru Tsukahara, Gerhard Gruender, Marina Sagud, Andreja Celofiga, Dragana Ignjatovic Ristic, Bruno B. Ortiz, Helio Elkis, Antonio J. Pacheco Palha, Adrian LLerena, Emilio Fernandez-Egea, Dan Siskind, Abraham Weizman, Rim Masmoudi, Shamin Mohd Saffian, Jonathan G. Leung, Peter F. Buckley, Stephen R. Marder, Leslie Citrome, Oliver Freudenreich, Christoph U. Correll, Daniel J. Muller, A. Elif Anil Yagcioglu, Flavian S. Radulescu, Wieslaw J. Cubala
Summary: This international guideline suggests improving clozapine package inserts globally by utilizing ancestry-based dosing and gradual titration to prevent potential toxicity and ADRs. It defines six personalized titration schedules for different populations and recommends monitoring inflammation globally.
PHARMACOPSYCHIATRY
(2022)
Review
Biochemistry & Molecular Biology
Ian McGrane, Edoardo Spina, Christoph Hiemke, Jose de Leon
Summary: This article systematically reviews the pharmacokinetic drug-drug interactions of oral haloperidol and summarizes recommendations for clinicians based on current knowledge.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY
(2022)
Letter
Pharmacology & Pharmacy
Madison S. Rauser, Ian R. McGrane
ANNALS OF PHARMACOTHERAPY
(2023)
Review
Medicine, Legal
Ian R. R. McGrane, Nathan C. C. Ramsbacher, William C. C. Rook, Faddy A. A. Omar
Summary: This systematic review examines the effects of METH and MDMA on driving performance. The study finds that experimental studies often show no significant safety signals, while observational studies highlight the safety risks associated with METH and MDMA use during driving. Common driving behaviors while using these drugs include errors in judgment, high-speed driving, failure to stop, inappropriate merging, lane weaving, and crashes.
JOURNAL OF FORENSIC SCIENCES
(2023)
Article
Pharmacology & Pharmacy
Ian R. McGrane, Trevor J. Campbell
Summary: A case of genitourinary symptoms in a 42-year-old male associated with atomoxetine use was reported. Discontinuation of atomoxetine led to rapid resolution of the adverse events. Literature review suggests that urine outflow obstruction-related adverse events occur more commonly in men compared to women.
JOURNAL OF PHARMACY PRACTICE
(2021)
Article
Pharmacology & Pharmacy
Ian R. McGrane, Laura A. Salyers, Jason R. Molinaro, Robert C. Munjal
Summary: This study provides preliminary insights into therapeutic drug monitoring of atypical antipsychotics in patients undergoing RYGB surgery. Findings suggest that oral extended-release drug formulations may not be the optimal choice, and nonoral antipsychotic formulations may be more suitable for some patients who have undergone RYGB surgery.
JOURNAL OF PHARMACY PRACTICE
(2021)
Article
Pharmacology & Pharmacy
David C. Nguyen, Tysen K. Timmer, Blair C. Davison, Ian R. McGrane
JOURNAL OF PHARMACY PRACTICE
(2019)
Article
Pharmacology & Pharmacy
Ian R. McGrane, Joshua G. Loveland, Jose de Leon
JOURNAL OF PHARMACY PRACTICE
(2018)