Brain energy metabolism and neuroinflammation in ageing APP/PS1-21 mice using longitudinal 18F-FDG and 18F-DPA-714 PET imaging

Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study

(2016) M. Brendel et al.   JOURNAL OF NUCLEAR MEDICINE

The Effects of Physiological and Methodological Determinants on 18F-FDG Mouse Brain Imaging Exemplified in a Double Transgenic Alzheimer Model

(2016) Steven Deleye et al.   Molecular Imaging

Quantification of [18F]DPA-714 Binding in the Human Brain: Initial Studies in Healthy Controls and Alzheimer'S Disease Patients

(2015) Sandeep SV Golla et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18 F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice

(2015) Bin Liu et al.   JOURNAL OF NEUROSCIENCE

PET Imaging of Translocator Protein (18 kDa) in a Mouse Model of Alzheimer's Disease Using N-(2,5-Dimethoxybenzyl)-2-18F-Fluoro-N-(2-Phenoxyphenyl)Acetamide

(2015) M. L. James et al.   JOURNAL OF NUCLEAR MEDICINE

Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein

(2015) C. H. Lyoo et al.   JOURNAL OF NUCLEAR MEDICINE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Amyloid load and translocator protein 18 kDa in APPswePS1-dE9 mice: a longitudinal study

(2015) Sophie Sérrière et al.   NEUROBIOLOGY OF AGING

In vivo imaging and characterization of [18F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET

(2015) Caterina Vicidomini et al.   NUCLEAR MEDICINE AND BIOLOGY

Innate Immunity Fights Alzheimer's Disease

(2015) Marie-Victoire Guillot-Sestier et al.   TRENDS IN NEUROSCIENCES

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease

(2014) Ignacio Pedrós et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Early Detection of Cerebral Glucose Uptake Changes in the 5XFAD Mouse

(2014) I.R. Macdonald et al.   Current Alzheimer Research

Microglia actions in Alzheimer’s disease

(2013) Stefan Prokop et al.   ACTA NEUROPATHOLOGICA

In vivo evaluation of amyloid deposition and brain glucose metabolism of 5XFAD mice using positron emission tomography

(2013) Santiago Rojas et al.   NEUROBIOLOGY OF AGING

Microglia Actively Regulate the Number of Functional Synapses

(2013) Kyungmin Ji et al.   PLoS One

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

(2013) Grietje Krabbe et al.   PLoS One

Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease

(2012) Sara Rapic et al.   NEUROBIOLOGY OF AGING

Amyloid Generation and Dysfunctional Immunoproteasome Activation with Disease Progression in Animal Model of Familial Alzheimer's Disease

(2011) Ester Aso et al.   BRAIN PATHOLOGY

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

(2011) Mikko Hiltunen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28

(2011) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Increased regional cerebral glucose uptake in an APP/PS1 model of Alzheimer's disease

(2011) Géraldine Poisnel et al.   NEUROBIOLOGY OF AGING

Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation

(2011) Nicolas Arlicot et al.   NUCLEAR MEDICINE AND BIOLOGY

Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models

(2010) Rachel M. Nicholson et al.   BRAIN RESEARCH

Neuroinflammatory processes in Alzheimer’s disease

(2010) Michael T. Heneka et al.   JOURNAL OF NEURAL TRANSMISSION

Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice

(2010) Niels J. Rupp et al.   NEUROBIOLOGY OF AGING

Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease

(2010) Feng Luo et al.   NEUROBIOLOGY OF AGING

Comparative Evaluation of the Translocator Protein Radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a Rat Model of Acute Neuroinflammation

(2009) F. Chauveau et al.   JOURNAL OF NUCLEAR MEDICINE

FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice

(2008) Jon Valla et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Multicenter Standardized 18F-FDG PET Diagnosis of Mild Cognitive Impairment, Alzheimer's Disease, and Other Dementias

(2008) L. Mosconi et al.   JOURNAL OF NUCLEAR MEDICINE

DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization

(2008) M. L. James et al.   JOURNAL OF NUCLEAR MEDICINE

PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET

(2008) Sriram Venneti et al.   NEUROBIOLOGY OF AGING

Realizing the potential of positron emission tomography with 18F-fluorodeoxyglucose to improve the treatment of Alzheimer’s disease

(2007) Norman L. Foster et al.   Alzheimers & Dementia