Review
Chemistry, Analytical
Alvaro Santana-Mayor, Ruth Rodriguez-Ramos, Antonio Herrera-Herrera, Barbara Socas-Rodriguez, Miguel Angel Rodriguez-Delgado
Summary: The development of sustainable chemistry has led to the emergence of new materials, with deep eutectic solvents (DESs) as a promising non-toxic alternative to toxic organic solvents, seeing a significant increase in their applications in analytical chemistry in recent years. The vast amount of information generated from studies associated with DESs needs continuous revision.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Food Science & Technology
Duygu Aslan Turker, Mahmut Dogan
Summary: This study aimed to extract anthocyanins from natural sources using deep eutectic solvents (DESs) and ultrasound-assisted extraction (UAE), proving to be a sustainable, effective, and green approach. Citric acid was chosen as the most promising hydrogen bond donor, with all tested DESs showing high biodegradability.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Bowen Hou, Rabia Durrani, Andre Delavault, Erwann Durand, Chenyu Jiang, Yiyang Long, Lili Song, Jian Song, Weiwei Huan, Fei Gao
Summary: This review focuses on the application of deep eutectic solvents (DESs) for protein extraction and purification, as well as their effects and principles on renewable biomasses. The study finds that DESs have the ability to maintain the activity and stability of extracted proteins, compared to traditional solvents. They show potential for reproducible and scalable protein extraction and purification, while enabling waste valorization in certain cases.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Physical
Andrey Shishov, Ivan Dubrovsky, Sergey Kirichenko, Andrey Bulatov
Summary: This study systematically investigated the stability and composition of deep eutectic solvents based on quaternary ammonium salts, terpenoids, and fatty acids in the aqueous phase. It was found that all two-component solvents transformed into three-component solvents in the presence of water. The influence of different hydrogen bond acceptors and donors on the formation of three-component solvents was also explored.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Engineering, Environmental
Ke Xue, Dingchao Fan, Xiang Wang, Zihao Dong, Zhaoyou Zhu, Peizhe Cui, Fanqing Meng, Yinglong Wang, Jianguang Qi
Summary: Due to the increasing scarcity of lithium resources, the recovery of lithium ions from water resources is an urgent problem. This paper proposes an environmentally friendly liquid-liquid extraction (LLE) process for lithium ion recovery. Nine hydrophobic deep eutectic solvents (HDESs) were formed using menthol (DLM) as a hydrogen bond acceptor (HBA) and octanoic acid, decanoic acid, and lauric acid (LA) as hydrogen bond donors (HBDs). HDESs synthesized with DLM and LA showed the best effect and were selected for the lithium extraction experiment. The single extraction efficiency of lithium ions was 80.69%, with optimized parameters such as rotational speed, equilibrium time, pH, molar ratio, and initial concentration.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Engineering, Environmental
Ziyan Li, Chaozheng Liu, Shu Hong, Hailan Lian, Changtong Mei, Juhyeon Lee, Qinglin Wu, Martin A. Hubbe, Mei-Chun Li
Summary: This review critically examines recent advances in the utilization of deep eutectic solvents (DESs) for the extraction and processing of chitin, highlighting the mechanisms, characterization methods, and governing factors involved. The challenges and limitations in this field are discussed, and potential perspectives and future directions are proposed.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Chemical
Sushil Patil, Sumana Paul, Ruma Gupta, Rama MohanaRao Dumpala, Preeti G. Goswami
Summary: In this study, a greener and cost-effective deep eutectic solvent (DES) was used for the selective extraction of hazardous plutonium from nuclear waste. The DES showed high radiation stability and efficient extraction capabilities. The method was successfully applied for the recovery and quantification of plutonium from real samples.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Physical
Mohammed Abobakr Al-Maari, Hanee F. Hizaddin, Adeeb Hayyan, Mohamed Kamel Hadj-Kali
Summary: Deep eutectic solvents (DESs) have been recognized as eco-friendly alternatives to conventional solvents. However, reliable methods for selecting task-specific DESs are limited. Using COSMO-RS, 126 DESs were screened based on their solubility capacity to estimate their potential use as plant seed oil extractants. The results showed that DESs with higher linoleic acid solubility had lower solubility for protein, and the similarity of DESs to both linoleic acid and protein was compared through sigma-profiles. DESs with high linoleic acid solubility could be used as individual solvents, while DESs with high protein solubility could be used as co-solvents with organic solvents.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Review
Plant Sciences
Dan Li
Summary: Natural deep eutectic solvents (NaDESs) are a promising green solvent with simple preparation, low cost, high solvency, and biocompatibility, which can be used for extracting phytonutrients and improving their properties.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Physical
Willyan Arajo da Costa, Vitor Troccoli Ribeiro, Dennys Correia da Silva, Alcides de Oliveira Wanderley Neto, Tereza Neuma de Castro Dantas, Mrcio Ferrari, Everaldo Silvino dos Santos
Summary: This study investigates the applicability of an antioxidant extract from Rhodotorula mucilaginosa yeast cells in the formulation of nanoemulsified systems. The systems showed stability in relation to centrifugal force action but were unsteady in kinetic terms. Rheological analysis demonstrated that the fluid dynamic behavior of nanoemulsions depended on the oil content in the system.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Multidisciplinary
Maninder Meenu, Vasudha Bansal, Sudha Rana, Nitya Sharma, Vinod Kumar, Vaishali Arora, Monika Garg
Summary: Anthocyanins are extracted using alternative solvents such as ionic liquids, deep eutectic solvents, and natural deep eutectic solvents, which are more environmentally friendly and efficient compared to conventional solvents. Acid-based deep eutectic solvents with 20-30% water content showed the highest anthocyanin extraction yield. Ultrasonic-assisted extraction was the most common and efficient method, and DES-based extracts exhibited the highest stability and antioxidant activity. Fruits and their by-products are the most commonly used samples, while cereal and legumes are less explored.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Chemistry, Physical
Gul Muhammad, Jingjing Wang, Wenlong Xiong, Yongkun Lv, Shen Zhang, Anqi Zhao, Parisa Jahanbakhsh-Bonab, Alexei Solovchenko, Jingliang Xu, Md. Asraful Alam
Summary: The present study aimed to develop a green and sustainable extraction procedure to obtain lutein from microalgae. A novel pretreatment process was established using a series of acidic and polyol based deep eutectic solvents (DESs). The lutein yield was optimized using response surface methodology (RSM) and one-factor-at-a-time approach.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Engineering, Chemical
Hongye Cheng, Zhiwen Qi
Summary: DESs are low-freezing mixtures formed by HBD and HBA, meeting specific separation requirements for different systems. This review discusses the applications of DESs in hard-to-separate liquid systems, separation mechanisms, DES recycling methods, and prospects for future research trends.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Engineering, Environmental
Ruizhuan Wang, Hao Qin, Zhen Song, Hongye Cheng, Lifang Chen, Zhiwen Qi
Summary: This study presents a rational approach for the selection of deep eutectic solvents (DES) in the synthesis of long-chain esters. Novel halogen-free DESs based on triazole and p-toluenesulfonic acid (PTSA) or benzenesulfonic acid (BSA) were prepared and characterized. Four dual solvent-catalysts were determined for esterification reactions with different ester carbon chain lengths. A rational DES selection strategy was formulated based on thermodynamic analysis and experimental results.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Food Science & Technology
Xizhe Fu, Di Wang, Tarun Belwal, Jing Xie, Yanqun Xu, Li Li, Ligen Zou, Lixia Zhang, Zisheng Luo
Summary: This study demonstrated a green, high-efficiency and multi-stability strategy for extracting anthocyanins from blueberry pomace using Choline chloride-Oxalic acid (ChOa) as a natural deep eutectic solvent (NADES) coupled with pulse-ultrasonication. Response surface methodology was employed to optimize extraction conditions, leading to a highly correlated experimental total anthocyanins content value with the theoretical result. Stability assays and analytical methods such as FT-IR, DSC, and UPLC-Triple-TOF/MS were used to characterize the protective effect of ChOa on anthocyanins and the properties of the extracts.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
