Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells

Knockdown of CUL4A inhibits invasion and induces apoptosis in osteosarcoma cells

(2015) Jia Song et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma

(2015) Yi-Lin Yang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Clinical significance of CUL4A in human prostate cancer

(2015) Gang Liu et al.   TUMOR BIOLOGY

CUL4A facilitates hepatocarcinogenesis by promoting cell cycle progression and epithelial-mesenchymal transition

(2015) Yingfang Pan et al.   Scientific Reports

CUL4A is overexpressed in human pituitary adenomas and regulates pituitary tumor cell proliferation

(2014) Yangyang Xu et al.   JOURNAL OF NEURO-ONCOLOGY

Lung tumourigenesis in a conditionalCul4Atransgenic mouse model

(2014) Yi-Lin Yang et al.   JOURNAL OF PATHOLOGY

CUL4A overexpression enhances lung tumor growth and sensitizes lung cancer cells to Erlotinib via transcriptional regulation of EGFR

(2014) Yunshan Wang et al.   Molecular Cancer

CUL4A Induces Epithelial–Mesenchymal Transition and Promotes Cancer Metastasis by Regulating ZEB1 Expression

(2013) Yunshan Wang et al.   CANCER RESEARCH

Involvement of CUL4A in Regulation of Multidrug Resistance to P-gp Substrate Drugs in Breast Cancer Cells

(2013) Yunshan Wang et al.   MOLECULES

CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth

(2013) T. Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human homologue forCaenorhabditis elegansCUL-4 protein overexpression is associated with malignant potential of epithelial ovarian tumours and poor outcome in carcinoma

(2012) Peter Birner et al.   JOURNAL OF CLINICAL PATHOLOGY

Cullin-4A·DNA Damage-binding Protein 1 E3 Ligase Complex Targets Tumor Suppressor RASSF1A for Degradation during Mitosis

(2011) Lingyan Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serum-Nutrient Starvation Induces Cell Death Mediated by Bax and Puma That Is Counteracted by p21 and Unmasked by Bcl-xL Inhibition

(2011) Frédérique Braun et al.   PLoS One

TGFBI expression is associated with a better response to chemotherapy in NSCLC

(2010) Marta Irigoyen et al.   Molecular Cancer

Cul4A is an oncogene in malignant pleural mesothelioma

(2009) Ming-Szu Hung et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors

(2008) Sergey V. Ivanov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis

(2008) D. L. Waning et al.   BLOOD

Down-regulation of stathmin is required for TGF-β inducible early gene 1 induced growth inhibition of pancreatic cancer cells

(2008) Lei Jiang et al.   CANCER LETTERS

p21 and p27: roles in carcinogenesis and drug resistance

(2008) Abde M. Abukhdeir et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

CDK Inhibitor p21 Is Degraded by a Proliferating Cell Nuclear Antigen-coupled Cul4-DDB1Cdt2Pathway during S Phase and after UV Irradiation

(2008) Hideo Nishitani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY