The X-linked juvenile retinoschisis protein retinoschisin is a novel regulator of mitogen-activated protein kinase signalling and apoptosis in the retina

Na+-K+-ATPase, a new class of plasma membrane receptors

(2016) Anita Aperia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome

(2016) Ran Du et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Nucleophosmin Mutants Promote Adhesion, Migration and Invasion of Human Leukemia THP-1 Cells through MMPs Up-regulation via Ras/ERK MAPK Signaling

(2016) Jingrong Xian et al.   International Journal of Biological Sciences

Do Src Kinase and Caveolin Interact Directly with Na,K-ATPase?

(2016) Eliyahu Yosef et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheO-glycosylated ectodomain of FXYD5 impairs adhesion by disrupting cell–cell trans-dimerization of Na,K-ATPase β1subunits

(2016) Elmira Tokhtaeva et al.   JOURNAL OF CELL SCIENCE

ERK1/2, MEK1/2 and p38 downstream signalling molecules impaired in CD56dimCD16+ and CD56brightCD16dim/− natural killer cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients

(2016) Teilah Kathryn Huth et al.   Journal of Translational Medicine

Paired octamer rings of retinoschisin suggest a junctional model for cell–cell adhesion in the retina

(2016) Gökhan Tolun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cog-Wheel Octameric Structure of RS1, the Discoidin Domain Containing Retinal Protein Associated with X-Linked Retinoschisis

(2016) Martin Bush et al.   PLoS One

Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer

(2015) Jingxing Ou et al.   JOURNAL OF CLINICAL INVESTIGATION

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Convergence of Human Genetics and Animal Studies: Gene Therapy for X-Linked Retinoschisis

(2015) Ronald A. Bush et al.   Cold Spring Harbor Perspectives in Medicine

SH2 Ligand-Like Effects of Second Cytosolic Domain of Na/K-ATPase α1 Subunit on Src Kinase

(2015) Moumita Banerjee et al.   PLoS One

Digitalis-induced cell signaling by the sodium pump: On the relation of Src to Na+/K+-ATPase

(2014) Marjorie E. Gable et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

(2014) Nicola J. Darling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Oxidized LDL Induces Apoptosis of Human Retinal Pigment Epithelium Through Activation of ERK-Bax/Bcl-2 Signaling Pathways

(2014) Qiu Yating et al.   CURRENT EYE RESEARCH

Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h−/− mouse

(2014) L C Byrne et al.   GENE THERAPY

HtrA1 is induced by oxidative stress and enhances cell senescence through p38 MAPK pathway

(2013) Supanji et al.   EXPERIMENTAL EYE RESEARCH

Peripheral expression of MAPK pathways in Alzheimer’s and Parkinson’s diseases

(2013) Shan Wang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

AMD-Associated Genes Encoding Stress-Activated MAPK Pathway Constituents Are Identified by Interval-Based Enrichment Analysis

(2013) John Paul SanGiovanni et al.   PLoS One

The Na-K-ATPase α1β1 heterodimer as a cell adhesion molecule in epithelia

(2012) Olga Vagin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Na,K-ATPase activity modulates Src activation: A role for ATP/ADP ratio

(2012) Karl M. Weigand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa model

(2012) Min-Ji Kang et al.   NATURE CELL BIOLOGY

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

ERK1/2 activation is a therapeutic target in age-related macular degeneration

(2012) S. Dridi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-linked juvenile retinoschisis: Clinical diagnosis, genetic analysis, and molecular mechanisms

(2012) Robert S. Molday et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Loss of MAP3K1 enhances proliferation and apoptosis during retinal development

(2011) M. Mongan et al.   DEVELOPMENT

The Na/K-ATPase is obligatory for membrane anchorage of retinoschisin, the protein involved in the pathogenesis of X-linked juvenile retinoschisis

(2011) Ulrike Friedrich et al.   HUMAN MOLECULAR GENETICS

Risk- and non-risk-associated variants at the 10q26 AMD locus influence ARMS2 mRNA expression but exclude pathogenic effects due to protein deficiency

(2011) Ulrike Friedrich et al.   HUMAN MOLECULAR GENETICS

ERK/MAPK Is Essential for Endogenous Neuroprotection in SCN2.2 Cells

(2011) Sumedha W. Karmarkar et al.   PLoS One

Foveomacular Schisis in Juvenile X-Linked Retinoschisis: An Optical Coherence Tomography Study

(2010) Jia Yu et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Quantitative fine-tuning of photoreceptor cis-regulatory elements through affinity modulation of transcription factor binding sites

(2010) J Lee et al.   GENE THERAPY

Identification of a Potential Receptor That Couples Ion Transport to Protein Kinase Activity

(2010) Qiqi Ye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential roles of ERK1/2 and JNK in retinal development and degeneration

(2010) Maryanne Donovan et al.   JOURNAL OF NEUROCHEMISTRY

Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouse

(2009) T K Park et al.   GENE THERAPY

Na,K-ATPase signal transduction triggers CREB activation and dendritic growth

(2009) L. Desfrere et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kavalactones Protect Neural Cells against Amyloid   Peptide-Induced Neurotoxicity via Extracellular Signal-Regulated Kinase 1/2-Dependent Nuclear Factor Erythroid 2-Related Factor 2 Activation

(2008) C. J. Wruck et al.   MOLECULAR PHARMACOLOGY

The Na/K-ATPase/Src complex and cardiotonic steroid-activated protein kinase cascades

(2008) Zhichuan Li et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY