Prenatal Exposure to an EDC Mixture, NeuroMix: Effects on Brain, Behavior, and Stress Responsiveness in Rats

Two Hits of EDCs Three Generations Apart: Effects on Social Behaviors in Rats, and Analysis by Machine Learning

(2022) Ross Gillette et al.   Toxics

Neurobehavioural and cognitive effects of prenatal exposure to organochlorine compounds in three year old children

(2021) Griet Vermeir et al.   BMC Pediatrics

Endocrine-disrupting chemicals and their effects on puberty

(2021) David Lopez-Rodriguez et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

PFAS and potential adverse impacts on bone and adipose tissue through interactions with PPAR-gamma

(2021) Andrea B Kirk et al.   ENDOCRINOLOGY

Perfluorooctane sulfonate interferes with non-genomic estrogen receptor signaling pathway, inhibits ERK1/2 activation and induces apoptosis in mouse spermatocyte-derived cells

(2021) Jianhua Qu et al.   TOXICOLOGY

Effects of endocrine‐disrupting chemicals on hypothalamic oxytocin and vasopressin systems

(2021) Michael P. Reilly et al.   Journal of Experimental Zoology Part A-Ecological and Integrative Physiology

Mixtures of persistent organic pollutants are found in vital organs of late gestation human fetuses

(2021) Richelle D. Björvang et al.   CHEMOSPHERE

A mixture of 15 phthalates and pesticides below individual chemical no observed adverse effect levels (NOAELs) produces reproductive tract malformations in the male rat

(2021) Justin M. Conley et al.   ENVIRONMENT INTERNATIONAL

Correlates of Persistent Endocrine-Disrupting Chemical Mixtures among Reproductive-Aged Black Women

(2021) Samantha Schildroth et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effects of an environmentally relevant PFAS mixture on dopamine and steroid hormone levels in exposed mice

(2021) Randi Grønnestad et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Obesogens: How They Are Identified and Molecular Mechanisms Underlying Their Action

(2021) Nicole Mohajer et al.   Frontiers in Endocrinology

Perfluoroalkyl Substances Stimulate Insulin Secretion by Islet β Cells via G Protein-Coupled Receptor 40

(2020) Wei-Ping Qin et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Per- and Polyfluoroalkyl Substances Differentially Inhibit Placental Trophoblast Migration and Invasion In Vitro

(2020) John T Szilagyi et al.   TOXICOLOGICAL SCIENCES

Associations between Exposure to Bisphenol A and Behavioral and Cognitive Function in Children with Attention-deficit/Hyperactivity Disorder: A Case-control Study

(2020) Seung-Jin Yoo et al.   Clinical Psychopharmacology and Neuroscience

Prenatal EDCs Impair Mate and Odor Preference and Activation of the VMN in Male and Female Rats

(2020) Morgan E Hernandez Scudder et al.   ENDOCRINOLOGY

Similar names, different results: Consistency of the associations between prenatal exposure to phthalates and parent-ratings of behavior problems in preschool children

(2020) Gillian England-Mason et al.   ENVIRONMENT INTERNATIONAL

Maternal organophosphate flame‐retardant exposure alters offspring feeding, locomotor and exploratory behaviors in a sexually‐dimorphic manner in mice

(2020) Sabrina N. Walley et al.   JOURNAL OF APPLIED TOXICOLOGY

Interaction of BDE-47 with nuclear receptors (NRs) based on the cytotoxicity: In vitro investigation and molecular interaction

(2020) Jiayi Song et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Disruption of global hypothalamic microRNA (miR) profiles and associated behavioral changes in California mice (Peromyscus californicus) developmentally exposed to endocrine disrupting chemicals

(2020) Sarabjit Kaur et al.   HORMONES AND BEHAVIOR

Early Life Stress Delays Sexual Maturation in Female Mice

(2019) Gabriela Manzano Nieves et al.   Frontiers in Molecular Neuroscience

Concentrations of perfluoroalkyl substances (PFASs) in human embryonic and fetal organs from first, second, and third trimester pregnancies

(2019) Linn Salto Mamsen et al.   ENVIRONMENT INTERNATIONAL

Peripubertal stress of male, but not female rats increases morphine-induced conditioned place preference and locomotion in adulthood

(2019) Dong-Mei Wang et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Protonation state effects of estrogen receptor α on the recognition mechanisms by perfluorooctanoic acid and perfluorooctane sulfonate: A computational study

(2019) Huiming Cao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Burden of Environmental Adversity Associated With Psychopathology, Maturation, and Brain Behavior Parameters in Youths

(2019) Raquel E. Gur et al.   JAMA Psychiatry

A Novel Approach to Chemical Mixture Risk Assessment—Linking Data from Population‐Based Epidemiology and Experimental Animal Tests

(2019) Carl‐Gustaf Bornehag et al.   RISK ANALYSIS

Role of polygenic risk in susceptibility to accelerated pubertal onset following chronic stress exposure

(2019) Ying Sun et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Exposure to di-(2-ethylhexyl) phthalate transgenerationally alters anxiety-like behavior and amygdala gene expression in adult male and female mice

(2019) Katherine M. Hatcher et al.   PHYSIOLOGY & BEHAVIOR

Adverse Childhood Experiences and Early Pubertal Timing Among Girls: A Meta-Analysis

(2019) Lei Zhang et al.   International Journal of Environmental Research and Public Health

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

(2019) Michele A. La Merrill et al.   Nature Reviews Endocrinology

Activation of human nuclear receptors by perfluoroalkylated substances (PFAS)

(2019) Anne-Cathrin Behr et al.   TOXICOLOGY IN VITRO

Mate choice, sexual selection, and endocrine-disrupting chemicals

(2018) Andrea C. Gore et al.   HORMONES AND BEHAVIOR

Application of a novel social choice paradigm to assess effects of prenatal endocrine-disrupting chemical exposure in rats (Rattus norvegicus).

(2018) Michael P. Reilly et al.   JOURNAL OF COMPARATIVE PSYCHOLOGY

Impairment of learning and memory performances induced by BPA: Evidences from the literature of a MoA mediated through an ED

(2018) Sakina Mhaouty-Kodja et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Early-life stress leads to sex-dependent changes in pubertal timing in rats that are reversed by a probiotic formulation

(2018) Caitlin S. M. Cowan et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Effects of the Endocrine-Disrupting Chemicals, Vinclozolin and Polychlorinated Biphenyls, on Physiological and Sociosexual Phenotypes in F2 Generation Sprague-Dawley Rats

(2018) Krittika Krishnan et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Passing experiences on to future generations: endocrine disruptors and transgenerational inheritance of epimutations in brain and sperm

(2018) Ross Gillette et al.   Epigenetics

Endocrine-disrupting chemicals: Effects on neuroendocrine systems and the neurobiology of social behavior

(2018) Andrea C. Gore et al.   HORMONES AND BEHAVIOR

Social and neuromolecular phenotypes are programmed by prenatal exposures to endocrine-disrupting chemicals

(2018) Viktoria Y. Topper et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants

(2017) Pierre Gaudriault et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Neural Mechanisms Underlying the Disruption of Male Courtship Behavior by Adult Exposure to Di(2-ethylhexyl) Phthalate in Mice

(2017) Carlos Dombret et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A Human Mixture Risk Assessment for Neurodevelopmental Toxicity Associated with Polybrominated Diphenyl Ethers Used as Flame Retardants

(2017) Olwenn V. Martin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Anxiety-like behaviors in adulthood are altered in male but not female rats exposed to low dosages of polychlorinated biphenyls in utero

(2017) Ross Gillette et al.   HORMONES AND BEHAVIOR

Direct and transgenerational effects of low doses of perinatal di-(2-ethylhexyl) phthalate (DEHP) on social behaviors in mice

(2017) Kayla M. Quinnies et al.   PLoS One

Adolescent environmental enrichment prevents behavioral and physiological sequelae of adolescent chronic stress in female (but not male) rats

(2017) Brittany L. Smith et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Prenatal exposure to an environmentally relevant phthalate mixture disrupts reproduction in F1 female mice

(2017) Changqing Zhou et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of intrauterine exposures to polychlorinated biphenyls, methylmercury, and lead on birth weight in Japanese male and female newborns

(2017) Nozomi Tatsuta et al.   Environmental Health and Preventive Medicine

Human amniotic fluid contaminants alter thyroid hormone signalling and early brain development in Xenopus embryos

(2017) Jean-Baptiste Fini et al.   Scientific Reports

Bisphenol A exposure and symptoms of anxiety and depression among inner city children at 10–12 years of age

(2016) Frederica Perera et al.   ENVIRONMENTAL RESEARCH

Environmental influences on reproductive health: the importance of chemical exposures

(2016) Aolin Wang et al.   FERTILITY AND STERILITY

Two-hit exposure to polychlorinated biphenyls at gestational and juvenile life stages: 1. Sexually dimorphic effects on social and anxiety-like behaviors

(2016) Margaret R. Bell et al.   HORMONES AND BEHAVIOR

Somatic and Neuroendocrine Changes in Response to Chronic Corticosterone Exposure During Adolescence in Male and Female Rats

(2016) E. T. Kaplowitz et al.   JOURNAL OF NEUROENDOCRINOLOGY

Two-hit exposure to polychlorinated biphenyls at gestational and juvenile life stages: 2. Sex-specific neuromolecular effects in the brain

(2016) Margaret R. Bell et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The effects of prenatal PCBs on adult social behavior in rats

(2015) Michael P. Reilly et al.   HORMONES AND BEHAVIOR

Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress

(2015) G. E. Hodes et al.   JOURNAL OF NEUROSCIENCE

Sex differences and stress across the lifespan

(2015) Tracy L Bale et al.   NATURE NEUROSCIENCE

Stress and the social brain: behavioural effects and neurobiological mechanisms

(2015) Carmen Sandi et al.   NATURE REVIEWS NEUROSCIENCE

Bisphenol A and phthalate endocrine disruption of parental and social behaviors

(2015) Cheryl S. Rosenfeld   Frontiers in Neuroscience

Long-term effects of combined neonatal and adolescent stress on brain-derived neurotrophic factor and dopamine receptor expression in the rat forebrain

(2014) Rachel A. Hill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Novel Model for Neuroendocrine Toxicology: Neurobehavioral Effects of BPA Exposure in a Prosocial Species, the Prairie Vole (Microtus ochrogaster)

(2014) Alana W. Sullivan et al.   ENDOCRINOLOGY

Sexually Dimorphic Effects of Ancestral Exposure to Vinclozolin on Stress Reactivity in Rats

(2014) Ross Gillette et al.   ENDOCRINOLOGY

Prenatal Phthalate Exposures and Neurobehavioral Development Scores in Boys and Girls at 6–10 Years of Age

(2014) Roni W. Kobrosly et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

In utero and peripubertal exposure to phthalates and BPA in relation to female sexual maturation

(2014) Deborah J. Watkins et al.   ENVIRONMENTAL RESEARCH

Sex-specific disruptions in spatial memory and anhedonia in a “two hit” rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling

(2014) Rachel A. Hill et al.   HIPPOCAMPUS

Sex-specific enhanced behavioral toxicity induced by maternal exposure to a mixture of low dose endocrine-disrupting chemicals

(2014) Marissa Sobolewski et al.   NEUROTOXICOLOGY

Bisphenol-A (BPA), BPA Glucuronide, and BPA Sulfate in Midgestation Umbilical Cord Serum in a Northern and Central California Population

(2013) Roy R. Gerona et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Antiandrogenic effect of perinatal exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate increases anxiety-like behavior in male rats during sexual maturation

(2013) S. Carbone et al.   HORMONES AND BEHAVIOR

Perinatal exposure to low-dose bisphenol A affects the neuroendocrine stress response in rats

(2013) Emily Panagiotidou et al.   JOURNAL OF ENDOCRINOLOGY

The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus

(2013) Agnete Overgaard et al.   NEUROTOXICOLOGY

Sex-specific epigenetic disruption and behavioral changes following low-dose in utero bisphenol A exposure

(2013) M. Kundakovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex-specific Esr2 mRNA expression in the rat hypothalamus and amygdala is altered by neonatal bisphenol A exposure

(2013) Jinyan Cao et al.   REPRODUCTION

Gestational Exposure to Bisphenol A Produces Transgenerational Changes in Behaviors and Gene Expression

(2012) Jennifer T. Wolstenholme et al.   ENDOCRINOLOGY

Reduced birth weight in relation to pesticide mixtures detected in cord blood of full-term infants

(2012) Erin L. Wickerham et al.   ENVIRONMENT INTERNATIONAL

Perinatal BPA exposure demasculinizes males in measures of affect but has no effect on water maze learning in adulthood

(2012) Bryan A. Jones et al.   HORMONES AND BEHAVIOR

Gestational and lactational exposure to bisphenol-A affects anxiety- and depression-like behaviors in mice

(2012) Xiaohong Xu et al.   HORMONES AND BEHAVIOR

Sex and dose-dependent effects of developmental exposure to bisphenol A on anxiety and spatial learning in deer mice (Peromyscus maniculatus bairdii) offspring

(2012) Eldin Jašarević et al.   HORMONES AND BEHAVIOR

Anxiogenic Effects of Developmental Bisphenol A Exposure Are Associated with Gene Expression Changes in the Juvenile Rat Amygdala and Mitigated by Soy

(2012) Heather B. Patisaul et al.   PLoS One

Effects of perinatal exposure to low dose of bisphenol A on anxiety like behavior and dopamine metabolites in brain

(2012) Shingo Matsuda et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Human biomonitoring of environmental chemicals—Early results of the 2007–2009 Canadian Health Measures Survey for males and females

(2011) Douglas A. Haines et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Endocrine Disruption of Brain Sexual Differentiation by Developmental PCB Exposure

(2010) Sarah M. Dickerson et al.   ENDOCRINOLOGY

Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice

(2010) Yu-Hua Tian et al.   SYNAPSE

Determination of the Di-(2-Ethylhexyl) Phthalate NOAEL for Reproductive Development in the Rat: Importance of the Retention of Extra Animals to Adulthood

(2010) Chad R. Blystone et al.   TOXICOLOGICAL SCIENCES

Social and non-social anxiety in adolescent and adult rats after repeated restraint

(2009) Tamara L. Doremus-Fitzwater et al.   PHYSIOLOGY & BEHAVIOR

Neonatal exposure to endocrine active compounds or an ERβ agonist increases adult anxiety and aggression in gonadally intact male rats

(2008) Heather B. Patisaul et al.   HORMONES AND BEHAVIOR

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols