Article
Emergency Medicine
Yihui Xing, Lingjun Zhou, Jianqiang Yu, Ziyang Wang, Zhiguo Ding, Chen Xie, Yuxiang Li, Fei Wang, Lu Tang
Summary: This meta-analysis investigated the analgesic efficacy and safety of nitrous oxide (N2O) in managing pain in adults in the emergency department (ED). The results showed that N2O had better analgesia compared to placebo and similar analgesia to other methods. However, N2O use was associated with a higher tendency of vomiting and dizziness.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Pediatrics
Dania Takagi, Saharon Less Elazari, Ayelet Shles, Hadas Yechiam, Dana Schujovitzky, Ehud Rosenbloom
Summary: This study found that transferring pediatric orthopedic cases to the pediatric emergency department resulted in a significant improvement in pain management for children, with a higher percentage receiving analgesic treatment and a more adequate treatment for pain severity. The pediatric emergency department also administered sedation more frequently, especially for dislocated fractures. Despite these improvements, complications and other factors such as length of stay and surgery rates were similar between the two departments.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Medicine, General & Internal
Melissandre Nicot, Ludovic Miraillet, Bruno Pereira, Jean-Baptiste Bouillon-Minois, Julien Raconnat, Fares Moustafa, Jeannot Schmidt, Sophia Sickout-Arondo, Lise Bernard, Pierre Clavelou, Xavier Moisset
Summary: The study showed that inhalation of a fixed 50% nitrous oxide-oxygen mixture did not reduce the pain caused by lumbar puncture in an emergency setting, but it did help to reduce anxiety and significantly increase patient satisfaction.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Geosciences, Multidisciplinary
Weiyi Tang, Amal Jayakumar, Xin Sun, John C. Tracey, Julia Carroll, Elizabeth Wallace, Jenna A. Lee, Levy Nathan, Bess Ward
Summary: The study found that N2O consumption rates are high in the seasonally anoxic environment of Chesapeake Bay, but generally undetectable in oxygenated waters. However, when the oxygen concentration was reduced in oxygenated samples, N2O consumption rates increased significantly, indicating the potential for N2O consumption in oxygenated environments. These new observations provide insights into N2O cycling processes and can be used to improve the modeling of N2O flux in estuaries.
GEOPHYSICAL RESEARCH LETTERS
(2022)
Article
Environmental Sciences
Todd S. Rosenstock, Andreas Wilkes
Summary: Improving agricultural activity data is a cost-effective option for reducing the uncertainty of greenhouse gas inventories and monitoring mitigation actions, meeting multiple national data needs, and bolstering investments. It's time to direct effort to this opportunity.
NATURE CLIMATE CHANGE
(2021)
Article
Agronomy
Do-Yeong Hur, Sung-Un Kim, Hyeon-Cheol Park, Keun-Ki Kim, Hong-Ju Son, Kwang-Min Lee, Yu-Jin Kim, Chang-Oh Hong
Summary: The study found that the application of bottom ash (BA) can reduce N2O emissions from upland arable soil and increase crop yield. With increasing BA application rates, N2O emissions decreased significantly and yield-scaled N2O emissions also decreased. The study suggests that an application rate of 200 Mg·ha(-1) of BA can reduce N2O emissions.
Article
Management
Michael Freeman, Susan Robinson, Stefan Scholtes
Summary: The study shows that the clinical decision unit (CDU) in the emergency department can significantly reduce unnecessary hospitalizations and wrongful patient discharges. CDU is particularly beneficial for high-risk patients, but there is a critical trade-off in resource allocation and congestion between the two gatekeeping stages. In this specific case, it is found that reducing the size of the first-stage ED to expand CDU capacity could further reduce unnecessary hospitalizations.
MANAGEMENT SCIENCE
(2021)
Article
Medicine, General & Internal
Catherine E. Varner, Alison L. Park, Joel G. Ray
Summary: Maternal prepregnancy emergency department (ED) use is associated with increased risk of infant ED use in the first year of life, especially for low-acuity ED use. This study suggests that maternal ED use may serve as a useful trigger for interventions aimed at reducing ED use in infancy.
Article
Emergency Medicine
Ma Concepcion Miguez, Clara Ferrero, Aristides Rivas, Jorge Lorente, Lucia Munoz, Rafael Maranon
Summary: This study compared the efficacy and safety of two pharmacological strategies for procedural sedation and analgesia in pediatric orthopedic procedures in the emergency department. The results showed similar efficacy between the two strategies, but FN strategy had a lower risk of adverse events and shorter ED length of stay compared to KM strategy.
PEDIATRIC EMERGENCY CARE
(2021)
Article
Emergency Medicine
Christopher O'Donnell, Ethan Molitch-Hou, Kyle James, Traci Leong, Michael Perry, Daniel Wood, Tahsin Masud, Brittany Thomas, Michael A. Ross, Nicole Franks
Summary: Fast track dialysis significantly reduced ED and hospital LOS, time to hemodialysis, and charges, but led to an increase in 30-day ED returns.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Anesthesiology
Jiajia Ma, Wei Xiong, Dongze Guo, Anxin Wang, Hui Qiao, Ruquan Han
Summary: The study compares the effect of sevoflurane-propofol-balanced anesthesia with propofol-based total intravenous anesthesia on the amplitude of FVEP during spine surgery. The results show that the effect of sevoflurane-propofol-balanced anesthesia on FVEP amplitude is noninferior to propofol-based TIVA under comparable BIS range.
ANESTHESIA AND ANALGESIA
(2022)
Article
Chemistry, Multidisciplinary
Aniruddha Dey, Jesse B. Gordon, Therese Albert, Sinan Sabuncu, Maxime A. Siegler, Samantha N. MacMillan, Kyle M. Lancaster, Pierre Moenne-Loccoz, David P. Goldberg
Summary: A new nonheme iron(II) complex was reported, which reacts with NO(g) to form a stable mononitrosyl complex. The mononitrosyl complex exhibits highly activated characteristics and can rapidly convert to N2O in the absence of an exogenous reductant.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Emergency Medicine
Maryann Mazer-Amirshahi, Peggy Ye
Summary: On June 24, 2022, the Supreme Court overturned Roe v. Wade, which will restrict legal abortion in many areas of the U.S., emphasizing the importance of effective emergency contraception. Methods discussed in this review include ulipristal, levonorgestrel, combined oral contraceptive pills, and copper intrauterine devices (IUDs). Emergency physicians need to understand the optimal use of these agents to prevent unwanted pregnancy, given the restricted abortion access.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Engineering, Environmental
Li-Kun Wang, Xueming Chen, Wei Wei, Qiuxiang Xu, Jing Sun, Giorgio Mannina, Lan Song, Bing-Jie Ni
Summary: This study found that both NO reductase and N2O reductase were inhibited at Fe(II)EDTA-NO concentration up to 20 mM, leading to N2O accumulation and enhanced N2O recovery efficiency. Under carbon-limiting conditions, N2O accumulation was further increased. Long-term experiments also revealed that Fe(II)EDTA-NO reduced microbial diversity and enriched Pseudomonas, which could be a typical microbe for NO-based denitrification technology.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Keita Yamashita, Zhendong Liu, Kenta Iyoki, Ching-Tien Chen, Shoko Miyagi, Yutaka Yanaba, Yusuke Yamauchi, Tatsuya Okubo, Toru Wakihara
Summary: The study demonstrates that ion-exchanged mordenite zeolites have high capacities for N2O adsorption under ambient conditions, providing insights for establishing a zeolite-based adsorption system.
CHEMICAL COMMUNICATIONS
(2021)
Article
Biochemical Research Methods
Chien-Chun Liu, Chih-Chuan Lin, Yung-Chin Hsiao, Po-Jung Wang, Jau-Song Yu
JOURNAL OF PROTEOMICS
(2018)
Article
Food Science & Technology
Chih-Chuan Lin, Yen-Chia Chen, Zhong Ning Leonard Goh, Chen-Ken Seak, Joanna Chen-Yeen Seak, Gao Shi-Ying, Chen-June Seak
Article
Environmental Sciences
Ying-Tse Yeh, Chun-Kuei Chen, Chih-Chuan Lin, Chia-Ming Chang, Kai-Ping Lan, Chorng-Kuang How, Hung-Tsang Yen, Yen-Chia Chen
Article
Food Science & Technology
Chien-Chun Liu, Ya-Han Yang, Yung-Chin Hsiao, Po-Jung Wang, Jo-Chuan Liu, Chien-Hsin Liu, Wen-Chin Hsieh, Chih-Chuan Lin, Jau-Song Yu
Summary: Snake envenomation is a serious public health issue, but the low venom concentration in plasma poses a challenge for venom detection and snakebite diagnosis. A simple method for rapid enrichment of venom proteins can enhance detection sensitivity.
Article
Food Science & Technology
Heng Yeh, Shi-Ying Gao, Chih-Chuan Lin
Summary: Wound necrosis and secondary infection are common complications after Taiwan cobra bites. The Cobra BITE study investigated the prevalence of wound infection, bacteriology, and corresponding antibiotic usage in patients, and established a scoring system to predict infection risk.
Article
Food Science & Technology
Chih-Chuan Lin, Chung-Hsien Chaou, Shi-Ying Gao
Summary: Local tissue swelling, inflammation, and wound necrosis are observed in Taiwan cobra bites, with factors like initial limb swelling, presentation time x serum level, initial necrosis, and patient presentation time influencing wound necrosis. Serum venom level alone cannot predict tissue necrosis, suggesting the importance of considering venom and time factors in future studies on antivenom efficacy.
Article
Toxicology
Chun-Kuei Chen, Yen-Chia Chen, Bruno Megarbane, Ying-Tse Yeh, Chung-Hsien Chaou, Chia-Hsun Chang, Chih-Chuan Lin
Summary: A reliable score to predict 28-day mortality in paraquat-poisoned patients at presentation was developed and validated in this study, independently from the ingestion time and serum paraquat measurement. The three chosen parameters for predicting mortality were urine paraquat level, white blood cells count, and blood glucose level. The AUC-ROCs of the APPM score in the derivation and validation cohorts were 0.91 and 0.94, respectively.
CLINICAL TOXICOLOGY
(2022)
Article
Toxicology
Chih-Chuan Lin, Te- Weng, Chip-Jin Ng, Chia-Pang Shih, Jui Hsu, Yuan-Chun Liao, Chen-Chang Yang, Cheng-Chung Fang
Summary: The Taiwan Emergency Department Drug Abuse Surveillance (TEDAS) project aims to assess the patterns of recreational drug use in patients presenting to emergency departments across the country. The preliminary results show that more than half of the recreational drugs detected were new psychoactive substances (NPS), and younger patients and women were more likely to have NPS detected in their urine samples. NPS-positive cases frequently experienced chest pain, tachycardia, and suicide attempt/non-suicidal self-harm.
CLINICAL TOXICOLOGY
(2022)
Article
Toxicology
Te- Weng, Hsien-Yi Chen, Lengsu W. Chin, Hsin-Hui Chou, Meng-Huan Wu, Guan-yuan Chen, Ju-Yu Chen, Chia-Pang Shih, Chih-Chuan Lin, Cheng-Chung Fang
Summary: This study compared the clinical characteristics of meth/amphetamine and synthetic cathinone users presenting to the emergency department. The results showed that synthetic cathinone users were more likely to have tachycardia, hyperthermia, and rhabdomyolysis compared to meth/amphetamine users.
CLINICAL TOXICOLOGY
(2022)
Article
Environmental Sciences
Hsin-Tzu Yeh, Hsien-Yi Chen, Sung-Wei Liu, Te- Weng, Cheng-Chung Fang, Jiun-Hao Yu, Yen-Chia Chen, Yu-Jang Su, Shi-Ying Gao, Chih-Chuan Lin
Summary: This study aimed to identify predictors of mortality in illicit drug users involving Novel Psychoactive Substances (NPS) to improve patient care in emergency treatment. The results showed that age, consciousness, heart rate, respiratory rate, blood pressure, blood oxygen saturation, seizures, abnormal breath sounds, and certain biochemical indicators were associated with mortality. Risk stratification and determining the optimal treatment can help improve survival rates in illicit drug users.
Article
Toxicology
Chia -Cheng Wang, Chun-Hsiang Ou Yang, Chih-Po Hsu, Chien-Chun Liu, Jau-Song Yu, Chih-Hong Lo, Wen-Chih Fann, Yen -Chia Chen, Chih-Chuan Lin
Summary: In this study, the authors analyzed the changes in serum venom concentration before and after antivenom administration in Taiwan cobra snakebite patients. They found that antivenom can effectively reduce limb swelling but cannot decrease wound necrosis. Early debridement of the bite site wound is recommended to prevent extended tissue necrosis and improve limb outcome.
JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES
(2023)