First Recombinant High-Density Lipoprotein Particles Administration in a Severe ICU COVID-19 Patient, a Multi-Omics Exploratory Investigation

Altered high-density lipoprotein composition and functions during severe COVID-19

(2021) Floran Begue et al.   Scientific Reports

Relationship between lipoprotein concentrations and short-term and 1-year mortality in intensive care unit septic patients: results from the HIGHSEPS study

(2021) Sébastien Tanaka et al.   Annals of Intensive Care

Administration of the High-Density Lipoprotein Mimetic CER-001 for Inherited Lecithin–Cholesterol Acyltransferase Deficiency

(2021) Stanislas Faguer et al.   ANNALS OF INTERNAL MEDICINE

Low HDL and high triglycerides predict COVID-19 severity

(2021) Lluís Masana et al.   Scientific Reports

Low-density lipoprotein cholesterol levels are associated with poor clinical outcomes in COVID-19

(2021) Álvaro Aparisi et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Dyslipidemia Is Related to Mortality in Critical Patients With Coronavirus Disease 2019: A Retrospective Study

(2021) Jiang Yue et al.   Frontiers in Endocrinology

Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

(2021) Masoumeh Farahani et al.   BIOMEDICINE & PHARMACOTHERAPY

HDL proteome remodeling associates with COVID-19 severity

(2021) Douglas Ricardo Souza Junior et al.   Journal of Clinical Lipidology

The HDL mimetic CER‐001 remodels plasma lipoproteins and reduces kidney lipid deposits in inherited lecithin:cholesterol acyltransferase deficiency

(2021) Chiara Pavanello et al.   JOURNAL OF INTERNAL MEDICINE

Reconstituted High-density Lipoprotein Therapy Improves Survival in Mouse Models of Sepsis

(2020) Sébastien Tanaka et al.   ANESTHESIOLOGY

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypolipidemia is associated with the severity of COVID-19

(2020) Xiuqi Wei et al.   Journal of Clinical Lipidology

A high-throughput mass spectrometry–based assay for large-scale profiling of circulating human apolipoproteins

(2020) Valentin BLANCHARD et al.   JOURNAL OF LIPID RESEARCH

Letter to the Editor: Low-density lipoprotein is a potential predictor of poor prognosis in patients with coronavirus disease 2019

(2020) Junli Fan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches

(2020) Alexander V. Sorokin et al.   FASEB JOURNAL

No benefit of HDL mimetic CER-001 on carotid atherosclerosis in patients with genetically determined very low HDL levels

(2020) Kang H. Zheng et al.   ATHEROSCLEROSIS

Lipoprotein concentrations over time in the intensive care unit COVID-19 patients: Results from the ApoCOVID study

(2020) Sébastien Tanaka et al.   PLoS One

Oxidative Stress and Inflammation in COVID-19-Associated Sepsis: The Potential Role of Anti-Oxidant Therapy in Avoiding Disease Progression

(2020) Jesús Beltrán-García et al.   Antioxidants

Immature surfactant protein-B impairs the antioxidant capacity of HDL

(2019) Cristina Banfi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

High-density lipoprotein (HDL) particle size and concentration changes in septic shock patients

(2019) Sébastien Tanaka et al.   Annals of Intensive Care

Lipid metabolism impairment in patients with sepsis secondary to hospital acquired pneumonia, a proteomic analysis

(2019) Narendra Kumar Sharma et al.   Clinical Proteomics

HDL Cholesterol Efflux is Impaired in Older Patients with Early Sepsis

(2018) Faheem W. Guirgis et al.   SHOCK

HDL Mimetics Infusion and Regression of Atherosclerosis: Is It Still Considered a Valid Therapeutic Option?

(2018) I. Karalis et al.   Current Cardiology Reports

Effect of Serial Infusions of CER-001, a Pre-β High-Density Lipoprotein Mimetic, on Coronary Atherosclerosis in Patients Following Acute Coronary Syndromes in the CER-001 Atherosclerosis Regression Acute Coronary Syndrome Trial

(2018) Stephen J. Nicholls et al.   JAMA Cardiology

The CSL112-2001 trial: Safety and tolerability of multiple doses of CSL112 (apolipoprotein A-I [human]), an intravenous formulation of plasma-derived apolipoprotein A-I, among subjects with moderate renal impairment after acute myocardial infarction

(2018) C. Michael Gibson et al.   AMERICAN HEART JOURNAL

Low HDL levels in sepsis versus trauma patients in intensive care unit

(2017) Sébastien Tanaka et al.   Annals of Intensive Care

Proteomic study revealed cellular assembly and lipid metabolism dysregulation in sepsis secondary to community-acquired pneumonia

(2017) Narendra Kumar Sharma et al.   Scientific Reports

Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112Novelty and Significance

(2016) Svetlana A. Didichenko et al.   CIRCULATION RESEARCH

Recombinant HDL (Milano) protects endotoxin-challenged rats from multiple organ injury and dysfunction

(2015) Xinbo Zhang et al.   BIOLOGICAL CHEMISTRY

Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity

(2015) Tomáš Vaisar et al.   JOURNAL OF LIPID RESEARCH

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA

(2015) Ruud S. Kootte et al.   JOURNAL OF LIPID RESEARCH

CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice

(2013) Claudine Tardy et al.   ATHEROSCLEROSIS

HDL and endothelial protection

(2013) A Tran-Dinh et al.   BRITISH JOURNAL OF PHARMACOLOGY

High Density Lipoprotein Protects against Polymicrobe-induced Sepsis in Mice

(2013) Ling Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation modulates human HDL composition and function in vivo

(2012) Margarita de la Llera Moya et al.   ATHEROSCLEROSIS

4F, apolipoprotein AI mimetic peptide, attenuates acute lung injury and improves survival in endotoxemic rats

(2012) Woon Yong Kwon et al.   Journal of Trauma and Acute Care Surgery

Reconstituted HDL Elicits Marked Changes in Plasma Lipids Following Single-Dose Injection in C57Bl/6 Mice

(2011) Zhu Chen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

The apolipoprotein A-I mimetic peptide 4F prevents defects in vascular function in endotoxemic rats

(2010) Lijun Dai et al.   JOURNAL OF LIPID RESEARCH

Apolipoprotein A-I mimetic peptide treatment inhibits inflammatory responses and improves survival in septic rats

(2009) Zhenghao Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

HDL cholesterol protects against cardiovascular disease in both genders, at all ages and at all levels of risk

(2009) M.T. Cooney et al.   ATHEROSCLEROSIS

High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus

(2009) Brian G. Drew et al.   CIRCULATION

Reconstituted High-Density Lipoprotein Attenuates Platelet Function in Individuals With Type 2 Diabetes Mellitus by Promoting Cholesterol Efflux

(2009) Anna C. Calkin et al.   CIRCULATION

Changes in HDL-associated apolipoproteins relate to mortality in human sepsis and correlate to monocyte and platelet activation

(2009) Stefan Barlage et al.   INTENSIVE CARE MEDICINE

Reconstituted High-Density Lipoprotein Increases Plasma High-Density Lipoprotein Anti-Inflammatory Properties and Cholesterol Efflux Capacity in Patients With Type 2 Diabetes

(2009) Sanjay Patel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

High-Density Lipoprotein Reduces the Human Monocyte Inflammatory Response

(2008) Andrew J. Murphy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY