Endothelial Microparticles Derived from Primary Pulmonary Microvascular Endothelial Cells Mediate Lung Inflammation in Chronic Obstructive Pulmonary Disease by Transferring microRNA-126

Human umbilical cord mesenchymal stem cell-derived extracellular vesicles ameliorate airway inflammation in a rat model of chronic obstructive pulmonary disease (COPD)

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Extracellular vesicle-encapsulated microRNA-23a from dorsal root ganglia neurons binds to A20 and promotes inflammatory macrophage polarization following peripheral nerve injury

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Role of extracellular vesicles in chronic lung disease

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microRNA‐129 overexpression in endothelial cell‐derived extracellular vesicle influences inflammatory response caused by myocardial ischemia/reperfusion injury

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MiR-126, IL-7, CXCR1/2 receptors, inflammation and circulating endothelial progenitor cells: The study on targets for treatment pathways in a model of subclinical cardiovascular disease (type 1 diabetes mellitus)

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MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats

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microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3

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Pirfenidone mediates cigarette smoke extract induced inflammation and oxidative stress in vitro and in vivo

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Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk

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New Insights into the Role of NLRP3 Inflammasome in Pathogenesis and Treatment of Chronic Obstructive Pulmonary Disease

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CircTLK1 Downregulation Attenuates High Glucose-Induced Human Mesangial Cell Injury by Blocking the AKT/NF-κB Pathway Through Sponging miR-126-5p/miR-204-5p

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Compelling Interaction of Cigarette Smoking and Polygenetic Risk Emerges for Lung Function and COPD

(2021) Dana B. Hancock   JAMA Network Open

Extracellular vesicles as drug delivery systems: Why and how?

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Endothelial Cell Morphology Regulates Inflammatory Cells Through MicroRNA Transferred by Extracellular Vesicles

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Influences of Regulation of miR-126 on Inflammation,Th17/Treg Subpopulation Differentiation, and Lymphocyte Apoptosis through Caspase Signaling Pathway in Sepsis

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BMSC-derived exosomes alleviate smoke inhalation lung injury through blockade of the HMGB1/NF-κB pathway

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High-Mobility Group Box 1 (HMGB1) and Autophagy in Acute Lung Injury (ALI): A Review

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Airway inflammation in COPD- progress to precision medicine

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Chronic Obstructive Pulmonary Disease and Smoking Status — United States, 2017

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Baicalin Suppresses the Proliferation and Migration of Ox-LDL-VSMCs in Atherosclerosis through Upregulating miR-126-5p

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Cigarette smoke‐induced HMGB1 translocation and release contribute to migration and NF‐κB activation through inducing autophagy in lung macrophages

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Exosomes from Endothelial Progenitor Cells Improve the Outcome of a Murine Model of Sepsis

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Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model

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A Novel Murine Chronic Obstructive Pulmonary Disease Model and the Pathogenic Role of MicroRNA-21

(2018) Shengyang He et al.   Frontiers in Physiology

Lung mesenchymal stem cells-derived extracellular vesicles attenuate the inflammatory profile of Cystic Fibrosis epithelial cells

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Microvesicles-mediated communication between endothelial cells modulates, endothelial survival, and angiogenic function via transferring of miR-125a-5p

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MicroRNA-126 suppresses inflammation in endothelial cells under hyperglycemic condition by targeting HMGB1

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5-Aza-2'-deoxycytidine protects against emphysema in mice via suppressing p16Ink4a expression in lung tissue

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MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium

(2017) Camilla Cerutti et al.   Scientific Reports

MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells

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Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

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The roles of miRNAs as potential biomarkers in lung diseases

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Structural and functional characterization of endothelial microparticles released by cigarette smoke

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miR-126 promotes angiogenesis and attenuates inflammation after contusion spinal cord injury in rats

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Extracellular vesicle microRNA transfer in cardiovascular disease

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Smoking and chronic obstructive pulmonary disease in Chinese population: a meta-analysis

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MicroRNA regulation of the germinal center response

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Role of microRNAs and long-non-coding RNAs in CD4+T-cell differentiation

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Mangosteen xanthones mitigate ovalbumin-induced airway inflammation in a mouse model of asthma

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HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

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Expression of High-Mobility Group Box 1 and of Receptor for Advanced Glycation End Products in Chronic Obstructive Pulmonary Disease

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The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

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