Article
Cardiac & Cardiovascular Systems
Min Kim, Yoon Jung Park, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Hui-Nam Pak, Moon-Hyoung Lee
Summary: A 74-year-old woman with incessant wide complex tachycardia was successfully treated with radiofrequency catheter ablation. However, an asymptomatic pseudoaneurysm was detected at the ablation site two months after the procedure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Thomas Bonnin, Pierre Roumegou, Soumaya Sridi, Saagar Mahida, Aurelien Bustin, Josselin Duchateau, Romain Tixier, Nicolas Derval, Thomas Pambrun, Ghassen Chniti, Takamitsu Takagi, Tsukasa Kamakura, Philipp Krisai, Clementine Andre, Remi Chauvel, Meleze Hocini, Michel Haissaguerre, Pierre Jais, Hubert Cochet, Frederic Sacher
Summary: This study assessed the prevalence, risk factors, and management of intra-cardiac thrombus in patients referred for scar-related VT ablation. The results showed that 11% of patients had cardiac thrombi, highlighting the importance of systematic thrombus screening to minimize the risk of embolism.
Article
Cardiac & Cardiovascular Systems
Xiaoyong Xu, Ming Ye, Yaxun Sun, Qiang Liu, Fusheng Ma, Chenyang Jiang
Summary: Homologous ventricular separation, a rare arrhythmia characterized by two separated QRS waves, may occur after extensive substrate modification of scar-related VT. This case report demonstrates that CRT-D can correct the dyssynchronous ventricle caused by homologous ventricular separation, resulting in significant improvement in patient symptoms. The width of the intrinsic QRS complex was not recovered during an 18-month follow-up.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Johnatan Nissan, Avi Sabbag, Roy Beinart, Eyal Nof
Summary: Even after a successful ventricular tachycardia ablation, some patients still experience recurrent ventricular tachycardia during follow-up. A study in Israel analyzed 111 patients who underwent successful ablation and found that a low left ventricular ejection fraction (LVEF) and a high number of induced ventricular tachycardias were independent predictors of arrhythmia recurrence. These findings highlight the importance of close follow-up and aggressive treatment for patients at high risk of ventricular tachycardia recurrence.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Robert C. Ward, Martin van Zyl, Christopher V. DeSimone
Summary: Idiopathic ventricular tachycardia (VT) is a significant cause of morbidity and sometimes mortality in patients with structurally normal hearts. Proper diagnosis and treatment rely on understanding the mechanism, cardiac anatomy, and associated ECG patterns. Catheter ablation is an effective strategy for patients who cannot tolerate medications or when medications are ineffective. This review discusses specific approaches and considerations for safely and effectively ablating VT arising from various locations.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Angel Arenal, Pablo Avila, Javier Jimenez-Candil, Luis Tercedor, David Calvo, Fernando Arribas, Javier Fernandez-Portales, Jose Luis Merino, Antonio Hernandez-Madrid, Francisco J. Fernandez-Aviles, Antonio Berruezo
Summary: In patients with ischemic cardiomyopathy and an implantable cardioverter-defibrillator (ICD), catheter ablation and antiarrhythmic drugs (AADs) reduce ICD shocks, but the most effective approach remains uncertain.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Levio Quinto, Paula Sanchez, Francisco Alarcon, Paz Garre, Fatima Zaraket, Susana Prat-Gonzalez, Jose T. Ortiz-Perez, Rosario Jesus Perea, Eduard Guasch, Jose Maria Tolosana, Rodolfo San Antonio, Elena Arbelo, Marta Sitges, Josep Brugada, Antonio Berruezo, Lluis Mont, Ivo Roca-Luque
Summary: The study analyzed the role of LGE-CMR in predicting VT recurrence after ablation in 110 consecutive patients. Factors such as LV mass, septal LGE distribution, and transmural channels were found to be predictive of post-ablation VT recurrence.
Article
Cardiac & Cardiovascular Systems
Roderick Tung, Yumei Xue, Minglong Chen, Chenyang Jiang, Dalise Y. Shatz, Stephanie Besser, Hongde Hu, Fa-Po Chung, Shiro Nakahara, Young-Hoon Kim, Kazuhiro Satomi, Lishui Shen, Erpeng Liang, Hongtao Liao, Kai Gu, Ruhong Jiang, Jian Jiang, Yuichi Hori, Jong-Il Choi, Akiko Ueda, Yuki Komatsu, Shuichiro Kazawa, Kyoko Soejima, Shih-Ann Chen, Akihiko Nogami, Yan Yao
Summary: The study confirmed that early catheter ablation therapy for ventricular tachycardia (VT) at the time of implantable cardioverter defibrillator (ICD) implantation significantly reduced the composite primary outcome of VT recurrence, cardiovascular hospitalization, or death for patients with cardiomyopathy.
Article
Cardiac & Cardiovascular Systems
Ryan Kipp, Matthew Kalscheur, Ann M. Sheehy, Christie M. Bartels, Amy J. H. Kind, W. Ryan Powell
Summary: This study found that female patients, patients identifying as Black race, and patients living in the most disadvantaged neighborhoods are less likely to receive ablation during hospitalization with ventricular tachycardia (VT).
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Paolo Della Bella, Francesca Baratto, Pasquale Vergara, Patrizia Bertocchi, Matteo Santamaria, Pasquale Notarstefano, Leonardo Calo, Daniela Orsida, Luca Tomasi, Marcello Piacenti, Stefano Sangiorgio, Francesco Pentimalli, Etienne Pruvot, Joao de Sousa, Frederic Sacher, Massimo Tritto, Luca Rebellato, Thomas Deneke, Salvo Andrea Romano, Martina Nesti, Alessio Gargaro, Daniele Giacopelli, Giovanni Peretto, Andrea Radinovic
Summary: The study suggests that catheter ablation of ventricular tachycardia after the first appropriate shock is associated with reduced risk of combined death or worsening heart failure hospitalization, lower mortality, and fewer ICD shocks.
Article
Cardiac & Cardiovascular Systems
Pablo Salazar, Andrew D. Beaser, Gaurav A. Upadhyay, Zaid Aziz, Stephanie Besser, Dalise Y. Shatz, Hemal M. Nayak, Roderick Tung
Summary: This study reports the feasibility and efficacy of an empiric ablation strategy using pacemapping to guide the treatment of patients with drug-refractory ventricular fibrillation (VF) and polymorphic ventricular tachycardia (PMVT). The study found that in the absence of identifiable PVC triggers, interrogating the Purkinje network, papillary muscles, and outflow tract regions with pacemap matching can guide ablation and significantly reduce VF/PMVT therapy burden and antiarrhythmic drug utilization.
Article
Cardiac & Cardiovascular Systems
Eyal Nof, Petr Peichl, Predrag Stojadinovic, Martin Arceluz, Philippe Maury, Moshe Katz, Usha B. Tedrow, Robin M. Singh, Ryohsuke Narui, Roy M. John, William G. Stevenson, Roy Beinart, Avishay Grupper, Leonid Sternik, Jacob Lavee, Frederic Sacher, Josef Kautzner, Avi Sabbag
Summary: This study describes the clinical characteristics, procedural details, specific challenges, and outcomes of ventricular tachycardia ablation using the HeartMate3 (TM) (HM3) left ventricular assist device system. The study findings suggest that ventricular tachycardia ablation in HM3 patients is feasible and safe when performed in the appropriate setup. Long-term arrhythmia-free survival is acceptable, but non-inducibility of ventricular tachycardia at the end of the procedure may not predict long-term outcomes well.
Article
Cardiac & Cardiovascular Systems
Andrea Radinovic, Giovanni Peretto, Giuseppe Sgarito, Filippo Maria Cauti, Antonello Castro, Maria Lucia Narducci, Roberto Mantovan, Marco Scaglione, Francesco Solimene, Alice Scopinaro, Claudio Tondo, Giulia Filippini, Elisabetta Bianco, Aldo Bonso, Vittorio Calzolari, Federico Ferraris, Marco Zardini, Marcello Piacenti, Giuseppe D'Angelo, Francesco Bosica, Paolo Della Bella
Summary: This study evaluated a simplified catheter ablation strategy and compared the results with those of a single referral center. The standardized mapping and ablation technique reproduced the procedural outcomes in a multicenter prospective study, effectively reducing ventricular tachycardia (VT) recurrences in patients with four causes of cardiomyopathy.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Medicine, General & Internal
Chin-Yu Lin, Fa-Po Chung, Nwe Nwe, Yu-Cheng Hsieh, Cheng-Hung Li, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tze-Fan Chao, Jo-Nan Liao, Ting-Yung Chang, Ling Kuo, Cheng- Wu, Chih-Min Liu, Shin-Huei Liu, Wen-Han Cheng, Shih-Ann Chen
Summary: This study investigates the effect of amiodarone on ablation outcomes in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) undergoing catheter ablation for drug-refractory ventricular tachycardia (VT). The results showed that patients on amiodarone before ablation had worse outcomes than patients off amiodarone, especially those who had used amiodarone continuously.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Muthiah Subramanian, Auras R. Atreya, Daljeet Kaur Saggu, Sachin Yalagudri, Narasimhan Calambur
Summary: Catheter ablation of ventricular arrhythmias has evolved significantly in the past few decades. Advances in understanding the underlying substrate, pre-procedural imaging, and ablation techniques have improved outcomes. Planning, including ECG analysis and imaging, is important for safety and efficacy. Tailored ablation strategies, anesthesia choice, and hemodynamic support contribute to successful ablation. Advancements in substrate mapping and contact-sense technologies have further improved outcomes. It is crucial to use newer technology and ablation strategies with high peri-procedural safety for optimal long-term results.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jason S. Bradfield, Justin Hayase, Kevin Liu, John Moriarty, Stephen T. Kee, Duc Do, Olujimi A. Ajijola, Marmar Vaseghi, Jean Gima, Julie Sorg, Shelly Cote, Geraldine Pavez, Eric Buch, Houman Khakpour, Yuliya Krokhaleva, Carlos Macias, Osamu Fujimura, Noel G. Boyle, Kalyanam Shivkumar
Article
Cardiac & Cardiovascular Systems
Kalyanam Shivkumar, Noel G. Boyle
Editorial Material
Cardiac & Cardiovascular Systems
Jason S. Bradfield, Kalyanam Shivkumar
Editorial Material
Cardiac & Cardiovascular Systems
Jeremy P. Moore, Kalyanam Shivkumar
Article
Cardiac & Cardiovascular Systems
Bastiaan J. D. Boukens, Michael Dacey, Veronique M. F. Meijborg, Michiel J. Janse, Joseph Hadaya, Peter Hanna, M. Amer Swid, Tobias Opthof, Jeffrey L. Ardell, Kalyanam Shivkumar, Ruben Coronel
Summary: Enhanced sympathetic activity during acute ischemia causes arrhythmias, with a mechanism involving a diastolic current flowing from the ischemic to non-ischemic myocardium. Stimulation of the left stellate ganglion shortens repolarization in non-ischemic myocardium, leading to more negative T waves in the ischemic zone and ventricular premature beats from normal tissue nearby.
CARDIOVASCULAR RESEARCH
(2021)
Biographical-Item
Cardiac & Cardiovascular Systems
Kalyanam Shivkumar, Noel G. Boyle
Article
Medicine, Research & Experimental
Ching Zhu, Pradeep S. Rajendran, Peter Hanna, Igor R. Efimov, Guy Salama, Charless C. Fowlkes, Kalyanam Shivkumar
Summary: This study used a high-resolution pipeline and computer vision algorithms to investigate microstructural changes on the heart after myocardial infarction (MI) and their association with electrical dysfunction. The results established clear structure-function relationships and identified potential neural substrates for cardiac arrhythmia after MI, providing a framework for understanding arrhythmogenic mechanisms with microscopic precision.
Editorial Material
Neurosciences
Kalyanam Shivkumar, Zhilin Qu, Robert Harvey
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Computer Science, Information Systems
Cheng Ding, Ran Xiao, Duc H. Do, David Scott Lee, Randall J. Lee, Shadi Kalantarian, Xiao Hu
Summary: Photoplethysmography (PPG) is a common physiological measurement for monitoring cardiovascular conditions. However, PPG datasets often suffer from class imbalance, and to tackle this problem, a generative model called LSM-GAN is proposed as a data augmentation technique to balance the dataset and improve classifier training.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2023)
Article
Cardiac & Cardiovascular Systems
Duc H. H. Do, Katherine L. L. Bailey, Ryan Beyer, Samuel Neubuerger, Jason Bradfield, Kalyanam Shivkumar, Ali Nsair, Noel G. G. Boyle
Summary: This study aimed to evaluate the impact of hormone-induced arrhythmia and atrioventricular block on retransplant survival in heart transplant patients. The results showed that hormone-induced arrhythmia patients do not require pacemaker implantation, while pacemaker implantation can reduce the risk of death or retransplant in patients with atrioventricular block.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Breno Bernardes-Souza, Raj V. Bhatt, Aileen Joy S. Bayoneta, Jungsik Seo, John P. Finn, Shumpei Mori, Duc H. Do, Noel G. Boyle
Summary: This study retrospectively studied the data of 15 patients who underwent MRI with LBBP between January 2016 and October 2022. The results showed that MRI in patients with LBBP appears to be safe, with no occurrences of arrhythmias or other adverse effects.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Takanori Sato, Kyle Adlaka, Issam D. Moussa, Peter Hanna, Duc H. Do, Michael C. Fishbein, Kalyanam Shivkumar, Shumpei Mori
Summary: Understanding the anatomical details of the right ventricle is crucial for avoiding right ventricular perforation, and the use of progressive dissection and virtual and photographic endoscopic images can help reduce the likelihood of this complication.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Duc H. Do, Kyle O'Meara, Jiyoung Lee, Scott Meyer, Peter Hanna, Shumpei Mori, Michael C. Fishbein, Noel G. Boyle, Marcelo Elizari, Jason S. Brad fi Eld, Kalyanam Shivkumar
Summary: This study examines the association between ventricular parasystole and ventricular arrhythmias and conduction system abnormalities in patients with implantable cardioverter-defibrillators (ICDs). The findings suggest that ventricular parasystole is strongly associated with ventricular fibrillation (VF) and new conduction system abnormalities, indicating a potential link between VF and damage to the His-Purkinje system.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jason J. Yang, Xiao Hu, Noel G. Boyle, Duc H. Do
Summary: This review discusses strategies for patient risk stratification of in-hospital cardiac arrest and their challenges and limitations. Early intervention is crucial for preventing and improving survival from cardiac arrest, but detecting an impending cardiac arrest remains particularly challenging. Machine learning-derived early warning systems show promise in addressing issues of sensitivity and positive predictive value, but further clinical research and technological advancements are needed.
CURRENT CARDIOVASCULAR RISK REPORTS
(2021)
Article
Computer Science, Information Systems
Ran Xiao, Duc Do, Cheng Ding, Karl Meisel, Randall J. Lee, Xiao Hu