Neuromuscular Active Zone Structure and Function in Healthy and Lambert-Eaton Myasthenic Syndrome States

Hypothesis Relating the Structure, Biochemistry and Function of Active Zone Material Macromolecules at a Neuromuscular Junction

(2022) Joseph A. Szule   Frontiers in Synaptic Neuroscience

A high affinity, partial antagonist effect of 3,4-diaminopyridine mediates action potential broadening and enhancement of transmitter release at NMJs

(2021) Kristine S. Ojala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Frog Motor Nerve Terminal Has Very Brief Action Potentials and Three Electrical Regions Predicted to Differentially Control Transmitter Release

(2020) Scott P. Ginebaugh et al.   JOURNAL OF NEUROSCIENCE

Transmitter release site organization can predict synaptic function at the neuromuscular junction

(2018) Rozita Laghaei et al.   JOURNAL OF NEUROPHYSIOLOGY

Impact of spatiotemporal calcium dynamics within presynaptic active zones on synaptic delay at the frog neuromuscular junction

(2018) Anne E. Homan et al.   JOURNAL OF NEUROPHYSIOLOGY

Lambert-Eaton Myasthenic Syndrome

(2018) Vita G. Kesner et al.   NEUROLOGIC CLINICS

Presynaptic active zones of mammalian neuromuscular junctions: Nanoarchitecture and selective impairments in aging

(2018) Yomna Badawi et al.   NEUROSCIENCE RESEARCH

The Structure of Human Neuromuscular Junctions: Some Unanswered Molecular Questions

(2017) Clarke Slater   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular and Molecular Anatomy of the Human Neuromuscular Junction

(2017) Ross A. Jones et al.   Cell Reports

Small Cell Lung Cancer

(2017) Gregory P. Kalemkerian et al.   Journal of the National Comprehensive Cancer Network

Synapse-Level Determination of Action Potential Duration by K + Channel Clustering in Axons

(2016) Matthew J.M. Rowan et al.   NEURON

Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice

(2016) Hiroshi Nishimune et al.   Scientific Reports

New insights into short-term synaptic facilitation at the frog neuromuscular junction

(2015) Jun Ma et al.   JOURNAL OF NEUROPHYSIOLOGY

Transmitter release is evoked with low probability predominately by calcium flux through single channel openings at the frog neuromuscular junction

(2015) Fujun Luo et al.   JOURNAL OF NEUROPHYSIOLOGY

Complete reversal of Lambert-Eaton myasthenic syndrome synaptic impairment by the combined use of a K+channel blocker and a Ca2+channel agonist

(2014) Tyler B. Tarr et al.   JOURNAL OF PHYSIOLOGY-LONDON

Synaptic Pathophysiology and Treatment of Lambert-Eaton Myasthenic Syndrome

(2014) Tyler B. Tarr et al.   MOLECULAR NEUROBIOLOGY

Control and Plasticity of the Presynaptic Action Potential Waveform at Small CNS Nerve Terminals

(2014) Michael B. Hoppa et al.   NEURON

An Excess-Calcium-Binding-Site Model Predicts Neurotransmitter Release at the Neuromuscular Junction

(2013) Markus Dittrich et al.   BIOPHYSICAL JOURNAL

Evaluation of a Novel Calcium Channel Agonist for Therapeutic Potential in Lambert-Eaton Myasthenic Syndrome

(2013) T. B. Tarr et al.   JOURNAL OF NEUROSCIENCE

Organization and function of transmitter release sites at the neuromuscular junction

(2013) Stephen D. Meriney et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Are unreliable release mechanisms conserved from NMJ to CNS?

(2012) Tyler B. Tarr et al.   TRENDS IN NEUROSCIENCES

Clinical Dutch-English Lambert-Eaton Myasthenic Syndrome (LEMS) Tumor Association Prediction Score Accurately Predicts Small-Cell Lung Cancer in the LEMS

(2011) Maarten J. Titulaer et al.   JOURNAL OF CLINICAL ONCOLOGY

Active zone density is conserved during synaptic growth but impaired in aged mice

(2011) Jie Chen et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Calcium Channels Link the Muscle-Derived Synapse Organizer Laminin  2 to Bassoon and CAST/Erc2 to Organize Presynaptic Active Zones

(2011) J. Chen et al.   JOURNAL OF NEUROSCIENCE

Single-Pixel Optical Fluctuation Analysis of Calcium Channel Function in Active Zones of Motor Nerve Terminals

(2011) F. Luo et al.   JOURNAL OF NEUROSCIENCE

Active Zones and the Readily Releasable Pool of Synaptic Vesicles at the Neuromuscular Junction of the Mouse

(2011) R. Ruiz et al.   JOURNAL OF NEUROSCIENCE

The spatio-temporal characteristics of action potential initiation in layer 5 pyramidal neurons: a voltage imaging study

(2011) Marko A. Popovic et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lambert–Eaton myasthenic syndrome: from clinical characteristics to therapeutic strategies

(2011) Maarten J Titulaer et al.   LANCET NEUROLOGY

Regulation of transmitter release by Ca2+ and synaptotagmin: insights from a large CNS synapse

(2011) Olexiy Kochubey et al.   TRENDS IN NEUROSCIENCES

Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis

(2010) K. Mukherjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macromolecular connections of active zone material to docked synaptic vesicles and presynaptic membrane at neuromuscular junctions of mouse

(2009) Sharuna Nagwaney et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Lambert-Eaton Myasthenic Syndrome

(2008) Maarten J. Titulaer et al.   Annals of the New York Academy of Sciences

Lambert–Eaton myasthenic syndrome: Search for alternative autoimmune targets and possible compensatory mechanisms based on presynaptic calcium homeostasis

(2008) Masaharu Takamori   JOURNAL OF NEUROIMMUNOLOGY

Action potential initiation and propagation: Upstream influences on neurotransmission

(2008) G.J. Kress et al.   NEUROSCIENCE

Fast Monte Carlo Simulation Methods for Biological Reaction-Diffusion Systems in Solution and on Surfaces

(2008) Rex A. Kerr et al.   SIAM JOURNAL ON SCIENTIFIC COMPUTING