Elevated H3K4me3 Through MLL2-WDR82 upon Hyperglycemia Causes Jagged Ligand Dependent Notch Activation to Interplay with Differentiation State of Endothelial Cells

Endothelial-Mesenchymal Transition in Cardiovascular Disease

(2021) Zahra Alvandi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dynamic alterations of H3K4me3 and H3K27me3 at ADAM17 and Jagged‐1 gene promoters cause an inflammatory switch of endothelial cells

(2021) Yash T. Katakia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intermittent High Glucose Elevates Nuclear Localization of EZH2 to Cause H3K27me3-Dependent Repression of KLF2 Leading to Endothelial Inflammation

(2021) Sumukh Thakar et al.   Cells

The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition

(2020) Simone F. Glaser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Postprandial Glucose Spikes, an Important Contributor to Cardiovascular Disease in Diabetes?

(2020) Nordin M. J. Hanssen et al.   Frontiers in Cardiovascular Medicine

Endothelial cells and organ function: applications and implications of understanding unique and reciprocal remodelling

(2019) Moritz Reiterer et al.   FEBS Journal

Epigenetic Regulation of Endothelial-to-Mesenchymal Transition in Chronic Heart Disease

(2018) Melanie S. Hulshoff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

KLF2 in Regulation of NF-κB-Mediated Immune Cell Function and Inflammation

(2017) Prerana Jha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The molecular basis of endothelial cell plasticity

(2017) Elisabetta Dejana et al.   Nature Communications

MKL1 defines the H3K4Me3 landscape for NF-κB dependent inflammatory response

(2017) Liming Yu et al.   Scientific Reports

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

(2016) Solene M. Evrard et al.   Nature Communications

Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress

(2015) Jan-Renier A.J. Moonen et al.   CARDIOVASCULAR RESEARCH

Enhancer of zeste homolog-2 (EZH2) methyltransferase regulates transgelin/smooth muscle-22α expression in endothelial cells in response to interleukin-1β and transforming growth factor-β2

(2015) Monika Maleszewska et al.   CELLULAR SIGNALLING

miR-200b Mediates Endothelial-to-Mesenchymal Transition in Diabetic Cardiomyopathy

(2015) Biao Feng et al.   DIABETES

Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development

(2015) Sara L. Lewandowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial-to-mesenchymal transition drives atherosclerosis progression

(2015) Pei-Yu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

(2015) Florian Grebien et al.   Nature Chemical Biology

Constitutively active Notch1 signaling promotes endothelial-mesenchymal transition in a conditional transgenic mouse model

(2014) JU LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Yap1 Is Required for Endothelial to Mesenchymal Transition of the Atrioventricular Cushion

(2014) Hui Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): Differential expression of microRNAs during EndMT

(2012) Asish K. Ghosh et al.   CELLULAR SIGNALLING

Notch Initiates the Endothelial-to-Mesenchymal Transition in the Atrioventricular Canal through Autocrine Activation of Soluble Guanylyl Cyclase

(2011) Alex C.Y. Chang et al.   DEVELOPMENTAL CELL

Endothelial Dysfunction in Diabetes: The role of reparatory mechanisms

(2011) A. Avogaro et al.   DIABETES CARE

Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy

(2010) J. Li et al.   DIABETES

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail

(2009) D. Brasacchio et al.   DIABETES

Differential Regulation of Transforming Growth Factor β Signaling Pathways by Notch in Human Endothelial Cells

(2009) YangXin Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oscillating Glucose Is More Deleterious to Endothelial Function and Oxidative Stress Than Mean Glucose in Normal and Type 2 Diabetic Patients

(2008) A. Ceriello et al.   DIABETES

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

(2008) Kyle Niessen et al.   JOURNAL OF CELL BIOLOGY