Extracellular vesicles enclosed‐miR‐421 suppresses air pollution (PM 2.5 )‐induced cardiac dysfunction via ACE2 signalling

Intratracheally instillated diesel PM2.5 significantly altered the structure and composition of indigenous murine gut microbiota

(2021) Ying Liu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort

(2021) Siqi Zhang et al.   ENVIRONMENTAL POLLUTION

Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms

(2021) Tanina Arab et al.   Journal of Extracellular Vesicles

Mechanism of haze pollution in summer and its difference with winter in the North China Plain

(2021) Qianhui Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

(2020) Charles E. Evans et al.   ACTA NEUROPATHOLOGICA

Melatonin alleviates vascular calcification and ageing through exosomal miR‐204/miR‐211 cluster in a paracrine manner

(2020) Feng Xu et al.   JOURNAL OF PINEAL RESEARCH

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

PM2.5 exposure perturbs lung microbiome and its metabolic profile in mice

(2020) Jingli Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

RNA delivery by extracellular vesicles in mammalian cells and its applications

(2020) Killian O’Brien et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oxidative stress pathways of air pollution mediated toxicity: Recent insights

(2020) Roopesh Singh Gangwar et al.   Redox Biology

Exosomes: Multifaceted Messengers in Atherosclerosis

(2020) Hongyun Wang et al.   Current Atherosclerosis Reports

Urban airborne PM2.5-activated microglia mediate neurotoxicity through glutaminase-containing extracellular vesicles in olfactory bulb

(2020) Xiaoyu Chen et al.   ENVIRONMENTAL POLLUTION

Extracellular vesicles and cardiovascular system: Biomarkers and Cardioprotective Effectors

(2020) Saveria Femminò et al.   VASCULAR PHARMACOLOGY

Short-term personal and outdoor exposure to ultrafine and fine particulate air pollution in association with blood pressure and lung function in healthy adults

(2020) Erik van Nunen et al.   ENVIRONMENTAL RESEARCH

Short term Pm2.5 exposure caused a robust lung inflammation, vascular remodeling, and exacerbated transition from left ventricular failure to right ventricular hypertrophy

(2019) Wenhui Yue et al.   Redox Biology

PM2.5 air pollution and cause-specific cardiovascular disease mortality

(2019) Richard B Hayes et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Ambient Particulate Air Pollution and Daily Mortality in 652 Cities

(2019) Cong Liu et al.   NEW ENGLAND JOURNAL OF MEDICINE

MiR-421 inhibition protects H9c2 cells against hypoxia/reoxygenation-induced oxidative stress and apoptosis by targeting Sirt3

(2019) Yu Liu et al.   PERFUSION-UK

Exposure to ambient air pollution and the incidence of congestive heart failure and acute myocardial infarction: A population-based study of 5.1 million Canadian adults living in Ontario

(2019) Li Bai et al.   ENVIRONMENT INTERNATIONAL

Drivers of improved PM2.5 air quality in China from 2013 to 2017

(2019) Qiang Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of adeno-associated virus vectors for in vitro and in vivo applications

(2019) Toyokazu Kimura et al.   Scientific Reports

Inverse probability weighted distributed lag effects of short-term exposure to PM2.5 and ozone on CVD hospitalizations in New England Medicare participants - Exploring the causal effects

(2019) Xinye Qiu et al.   ENVIRONMENTAL RESEARCH

IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways

(2019) Martijn L. Manson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Short-term PM2.5 exposure induces sustained pulmonary fibrosis development during post-exposure period in rats

(2019) Baiyang Sun et al.   JOURNAL OF HAZARDOUS MATERIALS

Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2

(2019) Junling Gao et al.   Redox Biology

AMPKα2 deficiency exacerbates long-term PM 2.5 exposure-induced lung injury and cardiac dysfunction

(2018) Hongyun Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Long- and short-term air pollution exposure and measures of arterial stiffness in the Framingham Heart Study

(2018) Petter L.S. Ljungman et al.   ENVIRONMENT INTERNATIONAL

Association of short-term exposure to ambient air pollutants with exhaled nitric oxide in hospitalized patients with respiratory-system diseases

(2018) Huibin Guo et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PM2.5-induced lung inflammation in mice: Differences of inflammatory response in macrophages and type II alveolar cells

(2017) Miao He et al.   JOURNAL OF APPLIED TOXICOLOGY

Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation

(2017) Laura Pergoli et al.   Particle and Fibre Toxicology

Airborne PM2.5-Induced Hepatic Insulin Resistance by Nrf2/JNK-Mediated Signaling Pathway

(2017) Jinxia Xu et al.   International Journal of Environmental Research and Public Health

DDAH1 plays dual roles in PM2.5 induced cell death in A549 cells

(2016) Hongyun Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Exposure to Fine Particulate Air Pollution Is Associated With Endothelial Injury and Systemic InflammationNovelty and Significance

(2016) C. Arden Pope et al.   CIRCULATION RESEARCH

Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure

(2016) Vaibhav B. Patel et al.   CIRCULATION RESEARCH

Associations among plasma metabolite levels and short-term exposure to PM2.5 and ozone in a cardiac catheterization cohort

(2016) Susanne Breitner et al.   ENVIRONMENT INTERNATIONAL

Fine Particulate Matter Constituents, Nitric Oxide Synthase DNA Methylation and Exhaled Nitric Oxide

(2015) Renjie Chen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals

(2015) Rodosthenis S. Rodosthenous et al.   Particle and Fibre Toxicology

E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1

(2015) Kun Wang et al.   Nature Communications

Chronic obstructive pulmonary disease

(2015) Peter J. Barnes et al.   Nature Reviews Disease Primers

Computational Characterization of Exogenous MicroRNAs that Can Be Transferred into Human Circulation

(2015) Jiang Shu et al.   PLoS One

Angiotensin-converting enzyme 2 is subject to post-transcriptional regulation bymiR-421

(2014) Daniel W. Lambert et al.   CLINICAL SCIENCE

Inhalable Microorganisms in Beijing’s PM2.5 and PM10 Pollutants during a Severe Smog Event

(2014) Chen Cao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Expert position paper on air pollution and cardiovascular disease

(2014) David E. Newby et al.   EUROPEAN HEART JOURNAL

Epidemiological time series studies of PM2.5and daily mortality and hospital admissions: a systematic review and meta-analysis

(2014) R W Atkinson et al.   THORAX

PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells

(2013) Xiaobei Deng et al.   CELL BIOLOGY AND TOXICOLOGY

Alveolar epithelial cells: Master regulators of lung homeostasis

(2013) Loïc Guillot et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Relationship between Lung Inflammation and Cardiovascular Disease

(2012) Stephan Van Eeden et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Long-term Exposure to PM 2.5 and Incidence of Acute Myocardial Infarction

(2012) Jaime Madrigano et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Endothelial dysfunction in the pulmonary artery induced by concentrated fine particulate matter exposure is associated with local but not systemic inflammation

(2012) Ana Paula Davel et al.   TOXICOLOGY

ARID1A, a Factor That Promotes Formation of SWI/SNF-Mediated Chromatin Remodeling, Is a Tumor Suppressor in Gynecologic Cancers

(2011) B. Guan et al.   CANCER RESEARCH

Prolonged Exposure to Particulate Pollution, Genes Associated with Glutathione Pathways, and DNA Methylation in a Cohort of Older Men

(2011) Jaime Madrigano et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Subclinical atherosclerosis, airflow obstruction and emphysema: the MESA Lung Study

(2011) R.G. Barr et al.   EUROPEAN RESPIRATORY JOURNAL

Rate of Decline of Forced Vital Capacity Predicts Future Arterial Hypertension

(2011) David R. Jacobs et al.   HYPERTENSION

Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung

(2010) Alberto Izzotti et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Chronic obstructive pulmonary disease—An independent risk factor for long-term cardiac and cardiovascular mortality in patients with ischemic heart disease

(2009) Kei Nishiyama et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY