Article
Environmental Sciences
Renata M. P. Freitas, Barbara S. Linhares, Jerusa M. Oliveira, Joao Paulo Leite, Sergio Luis P. da Matta, Reggiani Goncalves, Mariella B. Freitas
Summary: The fungicide TEB induces oxidative stress in Neotropical fruit-eating bats, resulting in liver damage and hormonal imbalance. Co-administration of the F. carica plant extract attenuates some oxidative stress responses and liver damage in exposed bats.
Article
Environmental Sciences
Chunlian Yao, Lan Huang, Changsheng Li, Dongxing Nie, Yajie Chen, Xuanjun Guo, Niannian Cao, Xuefeng Li, Sen Pang
Summary: This study investigated the mixture acute toxicities of fenvalerate and tebuconazole on zebrafish and found that different mixing ratios of the two pesticides exhibited antagonistic or synergistic effects on the fish. Additionally, the mixture exposure also affected the swimming behavior of zebrafish larvae.
FRONTIERS IN ENVIRONMENTAL SCIENCE
(2022)
Article
Environmental Sciences
Keiza Priscila Enes dos Santos, Isabella Ferreira Silva, Brayan Jonas Mano-Sousa, Joaquim Mauricio Duarte-Almeida, Whocely Victor de Castro, Rosy Iara Maciel de Azambuja Ribeiro, Helio Batista Santos, Ralph Gruppi Thom
Summary: The study evaluated the effects of the pesticide abamectin on adult zebrafish through acute and chronic exposure. The results showed that abamectin caused morphological changes in the liver cells, decreased expression of HSP70 and P-gp, and affected the behavior patterns of the fish. This highlights the potential harm of indiscriminate pesticide use on non-target organisms.
Article
Biochemistry & Molecular Biology
Elif Kaval Oguz, Burcu Ergoz, Ahmet R. Oguz
Summary: The study found that exposure to sublethal concentrations of TEB resulted in histopathological changes in the gill, liver, and kidney tissues of Van fish.
CHEMISTRY AND ECOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ylenia Marino, Alessia Arangia, Ramona D'Amico, Marika Cordaro, Rosalba Siracusa, Daniela Impellizzeri, Enrico Gugliandolo, Roberta Fusco, Salvatore Cuzzocrea, Rosanna Di Paola
Summary: This study investigated the toxic effects of TEB on autoimmune myocarditis (AM). The results showed that TEB exposure aggravated cardiac damage induced by AM, increased inflammation, and increased fibrosis and collagen deposition. It also altered the balance of oxidative stress and antioxidant enzymes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Feifei Ma, Yang Li, Yige Yu, Zengqiang Li, Liben Lin, Quanxu Chen, Qiang Xu, Peipei Pan, Yiyan Wang, Ren-shan Ge
Summary: Exposure to tebuconazole in utero causes the proliferation of fetal Leydig cells, possibly through effects on cell autophagy and proliferation mechanisms.
Article
Environmental Sciences
Ana Lopez-Antia, Manuel E. Ortiz-Santaliestra, Francois Mougeot, Pablo R. Camarero, Rafael Mateo
Summary: Exposure to tebuconazole-treated seeds was found to affect the physiology and reproductive output of red-legged partridges, particularly at high doses. This highlights the need to revisit risk assessments for tebuconazole as a seed treatment in light of its potential effects on bird reproduction.
ENVIRONMENTAL POLLUTION
(2021)
Article
Agronomy
Yongfeng Cai, Zhijie Ren, Chengyue Li, Tingwei Cai, Chang Yu, Qinghong Zeng, Shun He, Jianhong Li, Hu Wan
Summary: This study found that several fungicides have insecticidal activity against Nilaparvata lugens, with tebuconazole having the highest activity. Furthermore, tebuconazole significantly inhibited the expression of certain genes and affected the diversity and function of symbiotic fungi in N. lugens. These findings illustrate the insecticidal mechanism of tebuconazole and provide important rationale for delaying insecticide resistance.
PEST MANAGEMENT SCIENCE
(2023)
Article
Environmental Sciences
Christian Nyrop Albers, Ulla Elisabeth Bollmann, Nora Badawi, Anders Risbjerg Johnsen
Summary: The experiment showed that leaching of 1,2,4-triazole from barley seeds coated with triazole fungicides is a possibility, but only a small percentage of the fungicides ended up as 1,2,4-triazole in the leachate. Therefore, when evaluating the leaching risks from pesticide applications in agriculture, both seed dressing pesticides and their degradation products should be taken into consideration.
Article
Spectroscopy
Zuzana Jurasekova, Annamaria Jutkova, Tibor Kozar, Jana Stanicova
Summary: Pesticide use has positive effects on agricultural production globally but may have negative impacts on organisms and human health. Preliminary studies, continuous monitoring, and the use of Raman spectroscopy for rapid and selective pollutant detection are essential.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Agronomy
Marija Kovacevic, Nikolina Stjepanovic, Luca Zelic, Zeljka Loncaric, Maria A. Tsiafouli
Summary: This study assessed the adverse effects of the triazole fungicide tebuconazole (TEB) on earthworms. The results showed that TEB delayed hatching and reduced body mass of newly hatched juveniles, but had no adverse effects on adult survival. However, it is important to note that these effects were observed at high concentrations, and TEB is safe for earthworms when used correctly.
Article
Plant Sciences
Kun Fan, Li Fu, Huimin Liu, Jianlu Qu, Guofu Zhang, Shouan Zhang, Kang Qiao
Summary: In this study, the sensitivity of Botryosphaeria dothidea to tebuconazole in different isolates collected from major apple production provinces in China between 2006 and 2014 was determined. Results showed that the resistance levels of B. dothidea to tebuconazole increased over time, and regular resistance monitoring and prudent fungicide use were recommended to prolong the lifespan of tebuconazole in managing apple ring rot.
Article
Food Science & Technology
Leisiane Pereira Marques, Artur Santos-Miranda, Julliane Vasconcelos Joviano-Santos, Jorge Lucas Teixeira-Fonseca, Fabiana da Silva Alcantara, Jaqueline Oliveira Sarmento, Danilo Roman-Campos
Summary: The fungicide Tebuconazole affects the sodium current of human cardiac sodium channels by reducing its amplitude in a concentration- and voltage-dependent manner. It alters the inactivation properties and recovery kinetics of the current, and enhances closed-state inactivation and use-dependent block. Furthermore, Tebuconazole reduces the increase in late sodium current induced by another insecticide. These findings suggest a new mechanism of cardiotoxicity attributed to Tebuconazole.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Food Science & Technology
Xiaowei Liu, Ying Han, Ouli Xiao, Weiye Cui, Jieyin Chen, Xiaofeng Dai, Minmin Li, Zhiqiang Kong
Summary: This study compared the effects of different digestive models, factors, and dietary supplements on the bioaccessibility of tebuconazole in table grapes. The main factor affecting bioaccessibility was found to be digestion time, with dietary fiber reducing bioaccessibility. Tebuconazole was observed to undergo carrier-free passive transport in permeable cells in the Caco-2 cell model. These findings have practical implications for evaluating the harmful levels of pollutants in the matrix on the human body.
Article
Environmental Sciences
Eleni Gianni, Dionisios Panagiotaras, Ioannis Giannakis, Dimitrios Papoulis, Vlasoula Bekiari, Georgios Panagopoulos, Petros Petrounias, Alexandros Kalarakis
Summary: Two different nanocatalysts with palygorskite-TiO2 ratios of 40-60 and 10-90 were developed for the photocatalytic degradation of the fungicide tebuconazole under aquatic conditions. The nanocomposites were characterized and the results showed better dispersion and higher photocatalytic activity for the palygorskite-TiO2 ratio of 40:60. The photocatalytic efficiency of the nanocomposites was significantly higher than Degussa P25, indicating their promising potential for fungicides' degradation in aquatic environments.
WATER AND ENVIRONMENT JOURNAL
(2023)
Article
Chemistry, Physical
Francesca Scarpelli, Loredana Ricciardi, Massimo La Deda, Elvira Brunelli, Alessandra Crispini, Mauro Ghedini, Nicolas Godbert, Iolinda Aiello
Summary: This study describes the synthesis and properties of a novel water-soluble Ir(III) complex, which forms highly ordered supramolecular gels in water and exhibits luminescent properties. X-ray diffraction revealed the structure of the lyotropic mesophase, showing a high degree of order.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Multidisciplinary
Vittoria Curcio, Rachele Macirella, Settimio Sesti, Daniela Pellegrino, Abdalmoiz I. M. Ahmed, Elvira Brunelli
Summary: Lead is a toxic element that can harm humans and wildlife. Using zebrafish as a model species, this study shows that zebrafish embryos and larvae can exhibit adaptive responses in early stages and serve as valuable early warning indicators for pollution.
APPLIED SCIENCES-BASEL
(2021)
Article
Anatomy & Morphology
Elvira Brunelli, Rachele Macirella, Vittoria Curcio, Biagio D'Aniello, Anna Di Cosmo
Summary: This study investigated the morpho-functional differences of Leydig cells (LCs) in the skin and gills of Lissotriton italicus larvae for the first time. The study found that LCs in both tissues showed the same morphological and ultrastructural features, although LCs in the skin were significantly larger. The proliferative ability of LCs varied between the two tissues. Additionally, the study demonstrated the involvement of LCs in water storage and transport, and found that the LCs cytoplasm is rich in glycoconjugates.
MICROSCOPY RESEARCH AND TECHNIQUE
(2022)
Article
Biochemistry & Molecular Biology
Vittoria Curcio, Rachele Macirella, Settimio Sesti, Abdalmoiz I. M. Ahmed, Federica Talarico, Antonio Tagarelli, Marcello Mezzasalma, Elvira Brunelli
Summary: Lead, a highly toxic pollutant with a tendency to bioaccumulate, is a major concern for both humans and wildlife. This study investigates the effects of low and environmentally relevant concentrations of lead on the gills of Danio rerio, a model species for human toxicity. The results show that even low doses of lead can disrupt osmoregulation, induce cell damage, and trigger pathological changes in the gills.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Marcello Mezzasalma, Elvira Brunelli, Gaetano Odierna, Fabio Maria Guarino
Summary: The study provides the first karyotype description of eight Uroplatus species, revealing chromosome diversity in terms of chromosome number, heterochromatin composition, and NORs localization. Chromosome reduction is proposed to have occurred through translocations of microchromosomes on larger chromosomes, with independent sex chromosome diversification in different genera.
Article
Environmental Sciences
Vittoria Curcio, Rachele Macirella, Settimio Sesti, Abdalmoiz I. M. Ahmed, Federica Talarico, Roberto Pizzolotto, Antonio Tagarelli, Marcello Mezzasalma, Elvira Brunelli
Summary: This study investigated the morphological and morphometric alterations induced by lead in early zebrafish development and revealed that the severity of malformations increased with increasing lead dose and exposure time. The study emphasizes the effectiveness of morphological biomarkers in detecting threatening situations and highlights the high sensitivity of zebrafish during the initial stages of development. Zebrafish embryos and larvae play a crucial role in risk assessment and environmental monitoring.
Article
Zoology
Marcello Mezzasalma, Elvira Brunelli, Gaetano Odierna, Fabio M. Guarino
Summary: Reptiles are excellent model organisms for studying karyotype and sex chromosome evolution due to their unique genomic and chromosomal characteristics. However, only a small fraction of reptile species have known karyotypes. In this study, we performed a comparative cytogenetic analysis on Elaphe quatuorlineata and Zamenis lineatus, and identified their karyotypes and chromosomal features. Our findings support the species status of Z. lineatus and provide further evidence for the progressive diversification model of sex chromosomes in reptiles.
ACTA HERPETOLOGICA
(2022)
Article
Engineering, Marine
Daniela Amelio, Filippo Garofalo, Elvira Brunelli, Gianfranco Santovito, Daniela Pellegrino
Summary: The Frank-Starling response is a significant intrinsic heart property that is highly noticeable in fish hearts due to their sensitivity to stretch. Nitric oxide plays a crucial role in the Frank-Starling response. Antarctic icefish has lower expression and activation of nitric oxide synthase compared to red-blooded Antarctic teleost species, indicating its unique involvement in the Frank-Starling response.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Review
Agriculture, Dairy & Animal Science
Marcello Mezzasalma, Elvira Brunelli, Gaetano Odierna, Fabio Maria Guarino
Summary: This article provides a comprehensive report on the presence of different types of polyploidy in tetrapods, with a particular focus on its genomic, evolutionary, and ecological diversity. It suggests that polyploidy is an important pathway of genomic evolution in tetrapods, occurring in most higher-taxa and displaying a variety of different forms, genomic configurations, and biological implications.
Article
Zoology
M. Mezzasalma, E. Brunelli, G. Odierna, F. M. Guarino
Summary: We conducted a molecular taxonomic analysis and comparative cytogenetic study on two snake species. The results revealed the chromosomal characteristics and sex chromosome systems of Hemorrhois hippocrepis and Malpolon monspessulanus. Additionally, we observed differences in the chromosome diversification patterns between Colubridae and Psammophiidae, suggesting a higher chromosome variability in Psammophiidae due to progressive reduction of chromosome numbers.
EUROPEAN ZOOLOGICAL JOURNAL
(2023)
Article
Environmental Sciences
Abdalmoiz I. M. Ahmed, Rachele Macirella, Federica Talarico, Vittoria Curcio, Giuseppe Trotta, Donatella Aiello, Naouel Gharbi, Marcello Mezzasalma, Elvira Brunelli
Summary: Strobilurins, including dimoxystrobin, are widely used fungicides that are relatively non-toxic to mammals and birds but highly toxic to aquatic biota. However, there is limited research on the impact of dimoxystrobin on terrestrial and aquatic species, especially fish. This study investigated the effects of environmentally relevant concentrations of dimoxystrobin on fish gills, revealing structural and functional alterations, as well as impairment of key enzymes involved in osmotic regulation and oxidative stress defense. The findings emphasize the importance of comprehensive evaluation of the toxic potential of agrochemical compounds and highlight the need for ecotoxicological tests before the introduction of new compounds to the market.
Article
Fisheries
Rachele Macirella, Vittoria Curcio, Abdalmoiz I. M. Ahmed, Federica Talarico, Settimio Sesti, Enrique Paravani, Lucia Odetti, Marcello Mezzasalma, Elvira Brunelli
Summary: In this study, we investigated the morphological and functional injuries induced in zebrafish liver by low concentrations of Pb. The results showed significant histological alterations and increased injuries with dose and exposure time. Pb administration also resulted in higher lipid content and upregulation of key genes related to metal detoxification and defense against oxidative stress.