TRC150094, a Novel Mitochondrial Modulator, Reduces Cardio-Metabolic Risk as an Add-On Treatment: a Phase-2, 24-Week, Multi-Center, Randomized, Double-Blind, Clinical Trial

PREVALENCE OF DYSGLYCEMIA-BASED CHRONIC DISEASE (DBCD) IN EUROPEAN POPULATION: A NEW PARADIGM TO ADDRESS DIABETES BURDEN. THE KARDIOVIZE STUDY

(2021) Juan P. Gonzalez-Rivas et al.   Endocrine Practice

Metabolic and Energy Imbalance in Dysglycemia-Based Chronic Disease

(2021) Sanjay Kalra et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

(2021) Deepa Joshi et al.   Frontiers in Pharmacology

Cardiometabolic-Based Chronic Disease, Addressing Knowledge and Clinical Practice Gaps

(2020) Jeffrey I. Mechanick et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Healthcare utilisation and expenditure patterns for cardio-metabolic diseases in South Asian cities: the CARRS Study

(2020) Priti Gupta et al.   BMJ Open

Role of Mitochondria in the Mechanism(s) of Action of Metformin

(2019) Guillaume Vial et al.   Frontiers in Endocrinology

DYSGLYCEMIA-BASED CHRONIC DISEASE: AN AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS POSITION STATEMENT

(2018) Jeffrey I. Mechanick et al.   Endocrine Practice

The Effect of a Diiodothyronine Mimetic on Insulin Sensitivity in Male Cardiometabolic Patients: A Double-Blind Randomized Controlled Trial

(2014) Fleur van der Valk et al.   PLoS One

Metabolic effects of the iodothyronine functional analogue TRC150094 on the liver and skeletal muscle of high-fat diet fed overweight rats: an integrated proteomic study

(2012) Elena Silvestri et al.   Molecular BioSystems

TRC150094 attenuates progression of nontraditional cardiovascular risk factors associated with obesity and type 2 diabetes in obese ZSF1 rats

(2011) Shitalkumar Zambad et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet

(2010) Federica Cioffi et al.   FASEB JOURNAL

Daytime and Nighttime Blood Pressure as Predictors of Death and Cause-Specific Cardiovascular Events in Hypertension

(2007) Robert H. Fagard et al.   HYPERTENSION